| MeSH term | MeSH ID | Detail |
|---|---|---|
| Nerve Degeneration | D009410 | 53 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Medulloblastoma | D008527 | 22 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Eye Abnormalities | D005124 | 7 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yeh MW et al. | Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine. | 2000 | J. Immunol. | pmid:10754324 |
| Paolucci C et al. | Nitric oxide inhibits the tumor necrosis factor alpha -regulated endocytosis of human dendritic cells in a cyclic GMP-dependent way. | 2000 | J. Biol. Chem. | pmid:10777484 |
| Tomita H et al. | Ceramide-induced cell death in cultured rat retinal pigment epithelial cells. | 2000 | Tohoku J. Exp. Med. | pmid:10778806 |
| Takao N et al. | Protective roles for ATM in cellular response to oxidative stress. | 2000 | FEBS Lett. | pmid:10781820 |
| De Nadai C et al. | Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10792026 |
| Meadows KA et al. | Tumor necrosis factor-alpha-induced apoptosis is associated with suppression of insulin-like growth factor binding protein-5 secretion in differentiating murine skeletal myoblasts. | 2000 | J. Cell. Physiol. | pmid:10797307 |
| Raisova M et al. | Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release. | 2000 | FEBS Lett. | pmid:10802053 |
| Tavarini S et al. | Sphingomyelinase metabolites control survival and apoptotic death in SH-SY5Y neuroblastoma cells. | 2000 | Neurosci. Lett. | pmid:10806317 |
| Chik CL et al. | Ceramide inhibits L-type calcium channel currents in rat pinealocytes. | 1999 | Adv. Exp. Med. Biol. | pmid:10810500 |
| Knapp KM and English BK | Ceramide-mediated stimulation of inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF) accumulation in murine macrophages requires tyrosine kinase activity. | 2000 | J. Leukoc. Biol. | pmid:10811015 |