Lecour S et al. |
Ceramide-induced preconditioning involves reactive oxygen species. |
2006 |
Life Sci. |
pmid:16293265
|
Bianchi K et al. |
Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1alpha. |
2006 |
Cell Death Differ. |
pmid:16239931
|
Kolettas E et al. |
Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: role of p53 in the ceramide response. |
2006 |
Arch. Biochem. Biophys. |
pmid:16297852
|
Detre C et al. |
Death or survival: membrane ceramide controls the fate and activation of antigen-specific T-cells depending on signal strength and duration. |
2006 |
Cell. Signal. |
pmid:16099142
|
Rath GM et al. |
Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway. |
2006 |
Int. J. Biochem. Cell Biol. |
pmid:16971166
|
Ghering AB and Davidson WS |
Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I. |
2006 |
J. Lipid Res. |
pmid:16990644
|
Kniep B et al. |
9-O-acetyl GD3 protects tumor cells from apoptosis. |
2006 |
Int. J. Cancer |
pmid:16432837
|
Wang J et al. |
Ceramide induces apoptosis via a peroxisome proliferator-activated receptor gamma-dependent pathway. |
2006 |
Apoptosis |
pmid:17036198
|
Aubert N et al. |
PACAP and C2-ceramide generate different AP-1 complexes through a MAP-kinase-dependent pathway: involvement of c-Fos in PACAP-induced Bcl-2 expression. |
2006 |
J. Neurochem. |
pmid:17026529
|
Chen S et al. |
Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes. |
2006 |
J. Neurochem. |
pmid:16524368
|
Tabarean IV et al. |
Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons. |
2006 |
Neuroscience |
pmid:16777343
|
Strle K et al. |
C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts. |
2006 |
Endocrinology |
pmid:16777978
|
Xin M and Deng X |
Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation. |
2006 |
J. Biol. Chem. |
pmid:16679323
|
Hughes PJ et al. |
Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways. |
2006 |
J. Cell. Biochem. |
pmid:16178010
|
German OL et al. |
Ceramide is a mediator of apoptosis in retina photoreceptors. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:16565407
|
Sparkman L et al. |
Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. |
2006 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:16183668
|
Zhang XF et al. |
Apoptosis of human colon carcinoma HT-29 cells induced by ceramide. |
2006 |
World J. Gastroenterol. |
pmid:16773715
|
Falluel-Morel A et al. |
[Effects of PACAP and C2-ceramide on motility of cerebellar granule neurons: the fastest is not the farthest]. |
2005 Aug-Sep |
Med Sci (Paris) |
pmid:16115451
|
Gutwein P et al. |
Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. |
2005 |
Clin. Cancer Res. |
pmid:15814625
|
Takai N et al. |
C2-ceramide exhibits antiproliferative activity and potently induces apoptosis in endometrial carcinoma. |
2005 |
Oncol. Rep. |
pmid:16211298
|
Jang GJ et al. |
C2-ceramide induces vasodilation in phenylephrine-induced pre-contracted rat thoracic aorta: role of RhoA/Rho-kinase and intracellular Ca2+ concentration. |
2005 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:16231160
|
Calatayud CA et al. |
Involvement of the ubiquitin-mediated proteolytic system in the signaling pathway induced by ceramide in primary astrocyte cultures. |
2005 |
Dev. Neurosci. |
pmid:16280636
|
Arboleda G et al. |
Metabolic activity: a novel indicator of neuronal survival in the murine dopaminergic cell line CAD. |
2005 |
J. Mol. Neurosci. |
pmid:16055947
|
Giltiay NV et al. |
Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1beta in hepatocytes. |
2005 |
J. Lipid Res. |
pmid:16106045
|
Falluel-Morel A et al. |
Pituitary adenylate cyclase-activating polypeptide prevents the effects of ceramides on migration, neurite outgrowth, and cytoskeleton remodeling. |
2005 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15695581
|
Kim SH et al. |
Induction of apoptosis in chicken oviduct cells by C2-ceramide. |
2005 |
Mol. Cells |
pmid:15879700
|
Townley HE et al. |
Ceramides induce programmed cell death in Arabidopsis cells in a calcium-dependent manner. |
2005 |
Biol. Chem. |
pmid:15843160
|
Goswami R et al. |
Ceramide regulation of the tumor suppressor phosphatase PTEN in rafts isolated from neurotumor cell lines. |
2005 |
J. Neurosci. Res. |
pmid:15968641
|
Woo KJ et al. |
Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells. |
2005 |
Apoptosis |
pmid:16215670
|
Yabu T et al. |
Thalidomide-induced antiangiogenic action is mediated by ceramide through depletion of VEGF receptors, and is antagonized by sphingosine-1-phosphate. |
2005 |
Blood |
pmid:15741222
|
Sot J et al. |
Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides. |
2005 |
Biochim. Biophys. Acta |
pmid:15904658
|
Hampel B et al. |
Differential regulation of apoptotic cell death in senescent human cells. |
2004 Nov-Dec |
Exp. Gerontol. |
pmid:15582287
|
Falluel-Morel A et al. |
Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells. |
2004 |
J. Neurochem. |
pmid:15569266
|
Jones EL et al. |
The 70 kilodalton heat shock protein is an inhibitor of apoptosis in prostate cancer. |
2004 |
Int J Hyperthermia |
pmid:15764345
|
Murase T et al. |
Ceramide enhances acrosomal exocytosis triggered by calcium and the calcium ionophore A23187 in boar spermatozoa. |
2004 |
J. Reprod. Dev. |
pmid:15647619
|
Pilane CM and LaBelle EF |
NO induced apoptosis of vascular smooth muscle cells accompanied by ceramide increase. |
2004 |
J. Cell. Physiol. |
pmid:15040013
|
Shayman JA et al. |
A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity. |
2004 |
Glycoconj. J. |
pmid:14973367
|
Suzuki E et al. |
Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert. |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15466700
|
d'Anglemont de Tassigny A et al. |
Volume-sensitive chloride channels (ICl,vol) mediate doxorubicin-induced apoptosis through apoptotic volume decrease in cardiomyocytes. |
2004 |
Fundam Clin Pharmacol |
pmid:15482374
|
Blázquez C et al. |
Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. |
2004 |
Cancer Res. |
pmid:15313899
|
Yao N et al. |
The mitochondrion--an organelle commonly involved in programmed cell death in Arabidopsis thaliana. |
2004 |
Plant J. |
pmid:15500474
|
Hayashi M et al. |
High sensitivity of fibroblast cell lines derived from LEC rats to heat treatment. |
2004 |
J. Vet. Med. Sci. |
pmid:15528845
|
Kawano Y et al. |
Synergistic effect of interleukin (IL)-1alpha and ceramide analogue on the production of IL-6, IL-8, and macrophage colony-stimulating factor by endometrial stromal cells. |
2004 |
Fertil. Steril. |
pmid:15474071
|
Park HW et al. |
Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells. |
2004 |
Exp. Mol. Med. |
pmid:15557813
|
Ito Y et al. |
Reduction of airway anion secretion via CFTR in sphingomyelin pathway. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474513
|
Schultz A and Larsson C |
Ceramide influences neurite outgrowth and neuroblastoma cell apoptosis regulated by novel protein kinase C isoforms. |
2004 |
J. Neurochem. |
pmid:15189345
|
Cao LC et al. |
Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity. |
2004 |
Kidney Int. |
pmid:15496160
|
Dawson G et al. |
Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death. |
2004 |
J. Neurochem. |
pmid:15189346
|
Mansfield PJ et al. |
Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTP gamma S-stimulated polymorphonuclear leukocytes. |
2004 |
Blood |
pmid:14615385
|
Jaiswal AS and Narayan S |
Reduced levels of the adenomatous polyposis coli (APC) protein are associated with ceramide-induced apoptosis of colon cancer cells. |
2004 |
J. Cancer Res. Clin. Oncol. |
pmid:15340841
|
Park IN et al. |
Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression. |
2004 |
Drug Metab. Dispos. |
pmid:15319326
|
Hatano M et al. |
Enhancement of C2-ceramide antitumor activity by small interfering RNA on X chromosome-linked inhibitor of apoptosis protein in resistant human glioma cells. |
2004 |
J. Neurosurg. |
pmid:15255262
|
Daido S et al. |
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. |
2004 |
Cancer Res. |
pmid:15205343
|
Perks CM et al. |
Prolactin acts as a potent survival factor for human breast cancer cell lines. |
2004 |
Br. J. Cancer |
pmid:15213724
|
Park IN et al. |
Ceramide negatively regulates glutathione S-transferase gene transactivation via repression of hepatic nuclear factor-1 that is degraded by the ubiquitin proteasome system. |
2004 |
Mol. Pharmacol. |
pmid:15155840
|
Fernandez S et al. |
Inhibition of IL-10 receptor function in alveolar macrophages by Toll-like receptor agonists. |
2004 |
J. Immunol. |
pmid:14764735
|
Niiro H et al. |
(3Z)-2-Acetylamino-3-octadecen-1-ol as a potent apoptotic agent against HL-60 cells. |
2004 |
Bioorg. Med. Chem. |
pmid:14697769
|
Hida A et al. |
Nitric oxide acts on the mitochondria and protects human endothelial cells from apoptosis. |
2004 |
J. Lab. Clin. Med. |
pmid:15454884
|
Kong JY and Rabkin SW |
Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate. |
2003 |
Arch. Biochem. Biophys. |
pmid:12667483
|
Willaime-Morawek S et al. |
C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis. |
2003 |
Neuroscience |
pmid:12770554
|
Shikata K et al. |
Synthesis of non-natural C2-homo-ceramide and its apoptotic activity against HL-60 cells. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12639542
|
Shack S et al. |
Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity. |
2003 |
Mol. Cell. Biol. |
pmid:12640124
|
Cotteret S et al. |
p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD. |
2003 |
Mol. Cell. Biol. |
pmid:12897128
|
Scorrano L et al. |
BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis. |
2003 |
Science |
pmid:12624178
|
Shikata K et al. |
Apoptotic activities of C2-ceramide and C2-dihydroceramide homologues against HL-60 cells. |
2003 |
Bioorg. Med. Chem. |
pmid:12788346
|
Koide N et al. |
C2-ceramide inhibits LPS-induced nitric oxide production in RAW 264.7 macrophage cells through down-regulating the activation of Akt. |
2003 |
J. Endotoxin Res. |
pmid:12803880
|
Siskind LJ et al. |
Enlargement and contracture of C2-ceramide channels. |
2003 |
Biophys. J. |
pmid:12944273
|
Maedler K et al. |
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. |
2003 |
Diabetes |
pmid:12606514
|
Stoica BA et al. |
Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. |
2003 |
Mol. Cell. Neurosci. |
pmid:12691738
|
Liu SJ and Kennedy RH |
Positive inotropic effect of ceramide in adult ventricular myocytes: mechanisms dissociated from its reduction in Ca2+ influx. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12730052
|
Wang XQ et al. |
Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress. |
2003 |
J. Cell. Sci. |
pmid:12679386
|
Itoh M et al. |
Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia. |
2003 |
Clin. Cancer Res. |
pmid:12538495
|
Darios F et al. |
Ceramide increases mitochondrial free calcium levels via caspase 8 and Bid: role in initiation of cell death. |
2003 |
J. Neurochem. |
pmid:12562509
|
Ito M |
Insulin or bFGF and C2 ceramide increase newborn rat retinal ganglion cell survival rate. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12565900
|
Cho YH et al. |
Potentiation of lipopolysaccharide-inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer binding protein beta in macrophages. |
2003 |
Mol. Pharmacol. |
pmid:12606757
|
Upham BL et al. |
Differential roles of 2, 6, and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis. |
2003 |
Cancer Lett. |
pmid:12609706
|
Mikati MA et al. |
Hippocampal programmed cell death after status epilepticus: evidence for NMDA-receptor and ceramide-mediated mechanisms. |
2003 |
Epilepsia |
pmid:12614382
|
Prinetti A et al. |
Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells. |
2003 |
J. Biol. Chem. |
pmid:12486134
|
Iwai K et al. |
Ceramide increases oxidative damage due to inhibition of catalase by caspase-3-dependent proteolysis in HL-60 cell apoptosis. |
2003 |
J. Biol. Chem. |
pmid:12511568
|
Sreenivasan Y et al. |
Mechanism of cytosine arabinoside-mediated apoptosis: role of Rel A (p65) dephosphorylation. |
2003 |
Oncogene |
pmid:12853972
|
Amati F et al. |
Analysis of intracellular distribution and apoptosis involvement of the Ufd1l gene product by over-expression studies. |
2003 |
Cell Biochem. Funct. |
pmid:12910480
|
Witting SR et al. |
Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1. |
2003 |
J. Biol. Chem. |
pmid:12890677
|
Ramos B et al. |
Prevalence of necrosis in C2-ceramide-induced cytotoxicity in NB16 neuroblastoma cells. |
2003 |
Mol. Pharmacol. |
pmid:12869656
|
Latorre E et al. |
Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide. |
2003 |
Eur. J. Biochem. |
pmid:12492473
|
Fillet M et al. |
Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity. |
2003 |
Biochem. Pharmacol. |
pmid:12754099
|
Hunsperger EA and Wilcox CL |
Caspase-3-dependent reactivation of latent herpes simplex virus type 1 in sensory neuronal cultures. |
2003 |
J. Neurovirol. |
pmid:12775421
|
Yakushiji K et al. |
Characterization of C2-ceramide-resistant HL-60 subline (HL-CR): involvement of PKC delta in C2-ceramide resistance. |
2003 |
Exp. Cell Res. |
pmid:12749866
|
Perks CM et al. |
Prolactin acts as a potent survival factor against C2-ceramide-induced apoptosis in human granulosa cells. |
2003 |
Hum. Reprod. |
pmid:14645190
|
Enomoto A et al. |
Decreased c-Myc expression and its involvement in X-ray-induced apoptotic cell death of human T-cell leukaemia cell line MOLT-4. |
2003 |
Int. J. Radiat. Biol. |
pmid:14555342
|
Gentil B et al. |
Commitment to apoptosis by ceramides depends on mitochondrial respiratory function, cytochrome c release and caspase-3 activation in Hep-G2 cells. |
2003 |
Mol. Cell. Biochem. |
pmid:14674699
|
Pascual M et al. |
Ceramide pathways modulate ethanol-induced cell death in astrocytes. |
2003 |
J. Neurochem. |
pmid:14713309
|
Kralik SF et al. |
Ceramide and glucosamine antagonism of alternate signaling pathways regulating insulin- and osmotic shock-induced glucose transporter 4 translocation. |
2002 |
Endocrinology |
pmid:11751589
|
Abousalham A et al. |
Cell-permeable ceramides preferentially inhibit coated vesicle formation and exocytosis in Chinese hamster ovary compared with Madin-Darby canine kidney cells by preventing the membrane association of ADP-ribosylation factor. |
2002 |
Biochem. J. |
pmid:11802796
|
Soltys CL et al. |
Phosphorylation of cardiac protein kinase B is regulated by palmitate. |
2002 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12181135
|
Decraene C et al. |
Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays. |
2002 |
Genome Biol. |
pmid:12186649
|
Zhang YH et al. |
Ceramide, a putative second messenger for nerve growth factor, modulates the TTX-resistant Na(+) current and delayed rectifier K(+) current in rat sensory neurons. |
2002 |
J. Physiol. (Lond.) |
pmid:12381813
|
Marques M et al. |
Identification of platelet-activating factor acetylhydrolase II in human skin. |
2002 |
J. Invest. Dermatol. |
pmid:12406338
|
Xiao AY et al. |
Slight impairment of Na+,K+-ATPase synergistically aggravates ceramide- and beta-amyloid-induced apoptosis in cortical neurons. |
2002 |
Brain Res. |
pmid:12419544
|
Shin CY et al. |
C(2)-ceramide-induced circular smooth muscle cell contraction involves PKC-epsilon and p44/p42 MAPK activation in cat oesophagus. Mitogen-activated protein kinase. |
2002 |
Cell. Signal. |
pmid:12220618
|
Preaux AM et al. |
Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2. |
2002 |
Hepatology |
pmid:12198653
|