|
|
|
|
pmid:
|
Perks CM et al. |
Activation of integrin and ceramide signalling pathways can inhibit the mitogenic effect of insulin-like growth factor I (IGF-I) in human breast cancer cell lines. |
1999 |
Br. J. Cancer |
pmid:10070857
|
Shinpo K et al. |
Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons. |
1999 |
Brain Res. |
pmid:10082875
|
Medvedev AE et al. |
Limited role of ceramide in lipopolysaccharide-mediated mitogen-activated protein kinase activation, transcription factor induction, and cytokine release. |
1999 |
J. Biol. Chem. |
pmid:10092612
|
Mahajan S et al. |
Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]. |
1999 |
J. Biol. Chem. |
pmid:10092645
|
MacPhee I and Barker PA |
Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation. |
1999 |
J. Neurochem. |
pmid:10098845
|
Blázquez C et al. |
The stimulation of ketogenesis by cannabinoids in cultured astrocytes defines carnitine palmitoyltransferase I as a new ceramide-activated enzyme. |
1999 |
J. Neurochem. |
pmid:10098887
|
Kovács P et al. |
Effect of C2 ceramide on the inositol phospholipid metabolism (uptake of 32P, 3H-serine and 3H-palmitic acid) and apoptosis-related morphological changes in Tetrahymena. |
1999 |
Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. |
pmid:10190048
|
Puranam KL et al. |
CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide. |
1999 |
Mol. Genet. Metab. |
pmid:10191118
|
Su X et al. |
Differential activation of phosphoinositide 3-kinase by endothelin and ceramide in colonic smooth muscle cells. |
1999 |
Am. J. Physiol. |
pmid:10198327
|
Tolleson WH et al. |
Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. |
1999 |
Int. J. Oncol. |
pmid:10200332
|
Alesse E et al. |
The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering. |
1998 |
Cell Death Differ. |
pmid:10200487
|
Lee BR and Um HD |
Hydrogen peroxide suppresses U937 cell death by two different mechanisms depending on its concentration. |
1999 |
Exp. Cell Res. |
pmid:10222135
|
Herr I et al. |
FK506 prevents stroke-induced generation of ceramide and apoptosis signaling. |
1999 |
Brain Res. |
pmid:10224298
|
Watton SJ and Downward J |
Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction. |
1999 |
Curr. Biol. |
pmid:10226029
|
Mengubas K et al. |
Ceramide-induced killing of normal and malignant human lymphocytes is by a non-apoptotic mechanism. |
1999 |
Oncogene |
pmid:10229201
|
Kim YH and Kim SS |
Increase of MnSOD expression and decrease of JNK activity determine the TNF sensitivity in bcl2-transfected L929 cells. |
1999 |
Cytokine |
pmid:10328866
|
Mengubas K et al. |
Killing of T lymphocytes by synthetic ceramide is by a nonapoptotic mechanism and is abrogated following mitogenic activation. |
1999 |
Exp. Cell Res. |
pmid:10328959
|
Taniwaki T et al. |
Ceramide induces apoptosis to immature cerebellar granule cells in culture. |
1999 |
Neurochem. Res. |
pmid:10344598
|
Masamune A et al. |
Helicobacter pylori-dependent ceramide production may mediate increased interleukin 8 expression in human gastric cancer cell lines. |
1999 |
Gastroenterology |
pmid:10348816
|
Pruschy M et al. |
Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells. |
1999 |
Br. J. Cancer |
pmid:10360645
|
Hisano N et al. |
Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells. |
1999 |
Blood |
pmid:10361127
|
Li PL et al. |
Effect of ceramide on KCa channel activity and vascular tone in coronary arteries. |
1999 |
Hypertension |
pmid:10373230
|
Stewart CE et al. |
Increased, not decreased activation of the insulin-like growth factor (IGF) receptor signalling pathway during ceramide-induced apoptosis. |
1999 |
Growth Horm. IGF Res. |
pmid:10373346
|
Jones BE et al. |
Ceramide induces caspase-independent apoptosis in rat hepatocytes sensitized by inhibition of RNA synthesis. |
1999 |
Hepatology |
pmid:10385659
|
Dallalio G et al. |
Inhibition of human erythroid colony formation by ceramide. |
1999 |
Exp. Hematol. |
pmid:10390188
|
Shinoda J et al. |
Effect of ceramide on interleukin-6 synthesis in osteoblast-like cells. |
1999 |
Cell. Signal. |
pmid:10400316
|
Buisson-Legendre N et al. |
Involvement of the 92-kDa gelatinase (matrix metalloproteinase-9) in the ceramide-mediated inhibition of human keratinocyte growth. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10403818
|
Brindley DN et al. |
Tumor necrosis factor-alpha and ceramides in insulin resistance. |
1999 |
Lipids |
pmid:10419100
|
Pahan K et al. |
Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. |
1999 |
J. Neurochem. |
pmid:10428046
|
Yoshimura S et al. |
Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death. |
1999 |
J. Neurochem. |
pmid:10428064
|
Scaffidi C et al. |
Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. |
1999 |
J. Biol. Chem. |
pmid:10428830
|
Woessmann W et al. |
An essential role for mitogen-activated protein kinases, ERKs, in preventing heat-induced cell death. |
1999 |
J. Cell. Biochem. |
pmid:10440934
|
Maile LA et al. |
The role of cell surface attachment and proteolysis in the insulin-like growth factor (IGF)-independent effects of IGF-binding protein-3 on apoptosis in breast epithelial cells. |
1999 |
Endocrinology |
pmid:10465274
|
Belaud-Rotureau MA et al. |
Ceramide-induced apoptosis occurs independently of caspases and is decreased by leupeptin. |
1999 |
Cell Death Differ. |
pmid:10467353
|
Askew DJ et al. |
Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis. |
1999 |
Cell Death Differ. |
pmid:10467354
|
Pirianov G et al. |
Potentiation by vitamin D analogs of TNFalpha and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2. |
1999 |
Cell Death Differ. |
pmid:10510471
|
Meroni SB et al. |
Effect of N-acetylsphingosine (C2) and the ceramidase inhibitor (1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol on the regulation of Sertoli cell function. |
1999 Sep-Oct |
J. Androl. |
pmid:10520574
|
Olivera A et al. |
Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. |
1999 |
J. Cell Biol. |
pmid:10545499
|
Park BJ et al. |
Effect of ceramide on apoptosis and phospholipase D activity in FRTL-5 thyroid cells. |
1999 |
Exp. Mol. Med. |
pmid:10551263
|
De Jonghe S et al. |
Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues. |
1999 |
Bioorg. Med. Chem. Lett. |
pmid:10560744
|
Shayman JA and Abe A |
1-O-acylceramide synthase. |
2000 |
Meth. Enzymol. |
pmid:10563315
|
Ruiz L et al. |
Delta9-tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism. |
1999 |
FEBS Lett. |
pmid:10570948
|
Zhang QH et al. |
Redistribution of cytochrome c is not an essential requirement in C2-ceramide induced apoptosis in HL-60 cells. |
1999 |
Life Sci. |
pmid:10573189
|
Fujikawa K et al. |
Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells. |
1999 |
Exp. Cell Res. |
pmid:10585289
|
Ito A et al. |
Possible involvement of cytochrome c release and sequential activation of caspases in ceramide-induced apoptosis in SK-N-MC cells. |
1999 |
Biochim. Biophys. Acta |
pmid:10590315
|
Ogura M and Handa S |
Induction of apoptosis by novel synthesized acylamides of human lymphocytes. |
2000 |
Biochim. Biophys. Acta |
pmid:10601700
|
Susen K et al. |
Nerve growth factor stimulates MAPK via the low affinity receptor p75(LNTR). |
1999 |
FEBS Lett. |
pmid:10606727
|
Schürmann A et al. |
p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis. |
2000 |
Mol. Cell. Biol. |
pmid:10611223
|
Abend M et al. |
Indications for an active process underlying spontaneous and radiation-induced micronucleation in L929 cells. |
1999 |
Int. J. Radiat. Biol. |
pmid:10622263
|
Sabatini M et al. |
Effects of ceramide on apoptosis, proteoglycan degradation, and matrix metalloproteinase expression in rabbit articular cartilage. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10623638
|
Micoli KJ et al. |
Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis. |
2000 |
J. Biol. Chem. |
pmid:10625668
|
Allan D |
Lipid metabolic changes caused by short-chain ceramides and the connection with apoptosis. |
2000 |
Biochem. J. |
pmid:10642519
|
Liu J et al. |
Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide. |
2000 |
Am. J. Physiol., Cell Physiol. |
pmid:10644522
|
Craighead M et al. |
Caspases mediate C2-ceramide-induced apoptosis of the human oligodendroglial cell line, MO3.13. |
2000 |
Neurosci. Lett. |
pmid:10653009
|
Davis MA et al. |
Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells. |
2000 |
Toxicol. Sci. |
pmid:10653520
|
Kristal BS and Brown AM |
Ganglioside GD3, the mitochondrial permeability transition, and apoptosis. |
1999 |
Ann. N. Y. Acad. Sci. |
pmid:10672258
|
Salinas M et al. |
Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells. |
2000 |
Mol. Cell. Neurosci. |
pmid:10673324
|
Tsushima H and Mori M |
In vivo evidence that activation of tyrosine kinase is a trigger for lipopolysaccharide-induced fever in rats. |
2000 |
Brain Res. |
pmid:10678764
|
Mihai R et al. |
C2-Ceramide increases cytoplasmic calcium concentrations in human parathyroid cells. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10679256
|
Migita K et al. |
Regulation of rheumatoid synovial cell growth by ceramide. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10694479
|
Galve-Roperh I et al. |
Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. |
2000 |
Nat. Med. |
pmid:10700234
|
Dawson G |
Mechanisms of apoptosis in embryonic cortical neurons (E6 and E7) in culture involve lipid signalling, protein phosphorylation and caspase activation. |
2000 Apr-Jun |
Int. J. Dev. Neurosci. |
pmid:10715579
|
Lobner D |
Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis? |
2000 |
J. Neurosci. Methods |
pmid:10720679
|
Kondo T et al. |
Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis. |
2000 |
J. Biol. Chem. |
pmid:10722733
|
Kim HS et al. |
Induction of apoptosis by all-trans-retinoic acid and C2-ceramide treatment in rat stromal-vascular cultures. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10733907
|
Cho S and Dawson G |
Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells. |
2000 |
J. Neurochem. |
pmid:10737604
|
Chan C and Goldkorn T |
Ceramide path in human lung cell death. |
2000 |
Am. J. Respir. Cell Mol. Biol. |
pmid:10745027
|
Brás A et al. |
Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells. |
2000 |
Cell Death Differ. |
pmid:10745271
|
Ahmed N and Berridge MV |
Ceramides that mediate apoptosis reduce glucose uptake and transporter affinity for glucose in human leukaemic cell lines but not in neutrophils. |
2000 |
Pharmacol. Toxicol. |
pmid:10752668
|
Yeh MW et al. |
Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine. |
2000 |
J. Immunol. |
pmid:10754324
|
Paolucci C et al. |
Nitric oxide inhibits the tumor necrosis factor alpha -regulated endocytosis of human dendritic cells in a cyclic GMP-dependent way. |
2000 |
J. Biol. Chem. |
pmid:10777484
|
Tomita H et al. |
Ceramide-induced cell death in cultured rat retinal pigment epithelial cells. |
2000 |
Tohoku J. Exp. Med. |
pmid:10778806
|
Takao N et al. |
Protective roles for ATM in cellular response to oxidative stress. |
2000 |
FEBS Lett. |
pmid:10781820
|
De Nadai C et al. |
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10792026
|
Meadows KA et al. |
Tumor necrosis factor-alpha-induced apoptosis is associated with suppression of insulin-like growth factor binding protein-5 secretion in differentiating murine skeletal myoblasts. |
2000 |
J. Cell. Physiol. |
pmid:10797307
|
Raisova M et al. |
Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release. |
2000 |
FEBS Lett. |
pmid:10802053
|
Tavarini S et al. |
Sphingomyelinase metabolites control survival and apoptotic death in SH-SY5Y neuroblastoma cells. |
2000 |
Neurosci. Lett. |
pmid:10806317
|
Chik CL et al. |
Ceramide inhibits L-type calcium channel currents in rat pinealocytes. |
1999 |
Adv. Exp. Med. Biol. |
pmid:10810500
|
Knapp KM and English BK |
Ceramide-mediated stimulation of inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF) accumulation in murine macrophages requires tyrosine kinase activity. |
2000 |
J. Leukoc. Biol. |
pmid:10811015
|
Enomoto A et al. |
Involvement of SAPK/JNK pathway in X-ray-induced rapid cell death of human T-cell leukemia cell line MOLT-4. |
2000 |
Cancer Lett. |
pmid:10822128
|
Posey SC et al. |
Failure of gelsolin overexpression to regulate lymphocyte apoptosis. |
2000 |
Blood |
pmid:10828033
|
Campbell V and Lynch MA |
The role of ceramide in the modulation of intracellular Ca2+ levels by interleukin 1 beta in rat cortical synaptosomes. |
2000 |
Cytokine |
pmid:10857764
|
Pignata C et al. |
Clustering of distinct autoimmune diseases associated with functional abnormalities of T cell survival in children. |
2000 |
Clin. Exp. Immunol. |
pmid:10886239
|
O'Byrne D and Sansom D |
Lack of costimulation by both sphingomyelinase and C2 ceramide in resting human T cells. |
2000 |
Immunology |
pmid:10886399
|
Allan D et al. |
Mechanisms by which short-chain ceramides cause apoptosis. |
1999 |
Biochem. Soc. Trans. |
pmid:10917615
|
Chae HJ et al. |
Dexamethasone suppresses tumor necrosis factor-alpha-induced apoptosis in osteoblasts: possible role for ceramide. |
2000 |
Endocrinology |
pmid:10919278
|
Young KW et al. |
Effect of dimethylsphingosine on muscarinic M(3) receptor signalling in SH-SY5Y cells. |
2000 |
Eur. J. Pharmacol. |
pmid:10940357
|
Fukunaga T et al. |
Implication of sphingolipid metabolism in the stability of the Golgi apparatus. |
2000 |
J. Cell. Sci. |
pmid:10954427
|
Jiang Z et al. |
Ceramides induce apoptosis in HeLa cells and enhance cytochrome c-induced apoptosis in Xenopus egg extracts. |
2000 |
Cell. Mol. Life Sci. |
pmid:10961348
|
Di Nardo A et al. |
Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes. |
2000 |
Br. J. Dermatol. |
pmid:10971319
|
Menné C et al. |
Ceramide-induced TCR up-regulation. |
2000 |
J. Immunol. |
pmid:10975817
|
Muriel MP et al. |
Mitochondrial free calcium levels (Rhod-2 fluorescence) and ultrastructural alterations in neuronally differentiated PC12 cells during ceramide-dependent cell death. |
2000 |
J. Comp. Neurol. |
pmid:10982470
|
Pahlavani MA and Vargas DM |
The effect of a ceramide analog, N-acetylsphingosine on the induction of proliferation and IL-2 synthesis in T cells from young and old F344 rats. |
2000 |
Immunopharmacology |
pmid:10996032
|
Hirokawa M et al. |
Induction of tissue factor production but not the upregulation of adhesion molecule expression by ceramide in human vascular endothelial cells. |
2000 |
Tohoku J. Exp. Med. |
pmid:10997557
|
Müller-Wieprecht V et al. |
Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha and 1 alpha, 25-dihydroxyvitamin D(3). |
2000 |
Arch. Dermatol. Res. |
pmid:11000289
|
Klapisz E et al. |
Sphingolipids and cholesterol modulate membrane susceptibility to cytosolic phospholipase A(2). |
2000 |
J. Lipid Res. |
pmid:11013311
|
Siskind LJ and Colombini M |
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. |
2000 |
J. Biol. Chem. |
pmid:11027675
|
Sautin Y et al. |
Ceramide-induced apoptosis of human thyroid cancer cells resistant to apoptosis by irradiation. |
2000 |
Thyroid |
pmid:11041449
|
Navarro P et al. |
Akt mediates insulin rescue from apoptosis in brown adipocytes: effect of ceramide. |
2000 |
Growth Horm. IGF Res. |
pmid:11042022
|