| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuronal Ceroid-Lipofuscinoses | D009472 | 5 associated lipids |
| Eye Abnormalities | D005124 | 7 associated lipids |
| Retinoblastoma | D012175 | 12 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Medulloblastoma | D008527 | 22 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lecour S et al. | Ceramide-induced preconditioning involves reactive oxygen species. | 2006 | Life Sci. | pmid:16293265 |
| Bianchi K et al. | Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1alpha. | 2006 | Cell Death Differ. | pmid:16239931 |
| Kolettas E et al. | Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: role of p53 in the ceramide response. | 2006 | Arch. Biochem. Biophys. | pmid:16297852 |
| Strle K et al. | C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts. | 2006 | Endocrinology | pmid:16777978 |
| Xin M and Deng X | Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation. | 2006 | J. Biol. Chem. | pmid:16679323 |
| German OL et al. | Ceramide is a mediator of apoptosis in retina photoreceptors. | 2006 | Invest. Ophthalmol. Vis. Sci. | pmid:16565407 |
| Sparkman L et al. | Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. | 2006 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:16183668 |
| Falluel-Morel A et al. | [Effects of PACAP and C2-ceramide on motility of cerebellar granule neurons: the fastest is not the farthest]. | 2005 Aug-Sep | Med Sci (Paris) | pmid:16115451 |
| Calatayud CA et al. | Involvement of the ubiquitin-mediated proteolytic system in the signaling pathway induced by ceramide in primary astrocyte cultures. | 2005 | Dev. Neurosci. | pmid:16280636 |
| Woo KJ et al. | Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells. | 2005 | Apoptosis | pmid:16215670 |