| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Retinoblastoma | D012175 | 12 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Neuronal Ceroid-Lipofuscinoses | D009472 | 5 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Leanza L et al. | Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines. | 2014 | Curr. Pharm. Des. | pmid:23701546 |
| Hsieh CT et al. | Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. | 2014 | Cell. Signal. | pmid:24650522 |
| Chiu TT et al. | Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance. | 2013 | J. Biol. Chem. | pmid:23640896 |
| Lee JT et al. | Homocysteine induces cerebral endothelial cell death by activating the acid sphingomyelinase ceramide pathway. | 2013 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:23665108 |
| Luther JA et al. | Neurotrophins regulate cholinergic synaptic transmission in cultured rat sympathetic neurons through a p75-dependent mechanism. | 2013 | J. Neurophysiol. | pmid:23114219 |
| Chen WF et al. | Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets. | 2013 | Haematologica | pmid:23065519 |
| Iwayama H and Ueda N | Role of mitochondrial Bax, caspases, and MAPKs for ceramide-induced apoptosis in renal proximal tubular cells. | 2013 | Mol. Cell. Biochem. | pmid:23543151 |
| Taheripak G et al. | Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells. | 2013 | Free Radic. Biol. Med. | pmid:24120971 |
| Li H et al. | Asymmetric dimethylarginine attenuates serum starvation-induced apoptosis via suppression of the Fas (APO-1/CD95)/JNK (SAPK) pathway. | 2013 | Cell Death Dis | pmid:24091673 |
| Pacheco A et al. | C2-phytoceramide perturbs lipid rafts and cell integrity in Saccharomyces cerevisiae in a sterol-dependent manner. | 2013 | PLoS ONE | pmid:24040213 |
| Guo L et al. | Sphingosine-1-phosphate inhibits ceramide-induced apoptosis during murine preimplantation embryonic development. | 2013 | Theriogenology | pmid:23731666 |
| Dekker MJ et al. | Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. | 2013 | Atherosclerosis | pmid:23466071 |
| Zhang X et al. | Asiatic acid protects primary neurons against C2-ceramide-induced apoptosis. | 2012 | Eur. J. Pharmacol. | pmid:22296759 |
| Li R et al. | [Effect of ceramide on GSTA1 in Caco-2 cells]. | 2012 | Yao Xue Xue Bao | pmid:22993865 |
| Sabirzhanov B et al. | Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. | 2012 | J. Neurochem. | pmid:22909049 |
| Sánchez-Mora RM et al. | PINK1 overexpression protects against C2-ceramide-induced CAD cell death through the PI3K/AKT pathway. | 2012 | J. Mol. Neurosci. | pmid:22212487 |
| Li R et al. | Specific phosphorylation of αA-crystallin is required for the αA-crystallin-induced protection of astrocytes against staurosporine and C2-ceramide toxicity. | 2012 | Neurochem. Int. | pmid:22414529 |
| Kim SK et al. | Palmitate induces RIP1-dependent necrosis in RAW 264.7 cells. | 2012 | Atherosclerosis | pmid:23084711 |
| Taniguchi M et al. | Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway. | 2012 | J. Biol. Chem. | pmid:23035115 |
| Kue CS et al. | C6-ceramide enhances Interleukin-12-mediated T helper type 1 cell responses through a cyclooxygenase-2-dependent pathway. | 2012 | Immunobiology | pmid:22112438 |