| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Retinoblastoma | D012175 | 12 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Neuronal Ceroid-Lipofuscinoses | D009472 | 5 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sabatini M et al. | Effects of ceramide on apoptosis, proteoglycan degradation, and matrix metalloproteinase expression in rabbit articular cartilage. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623638 |
| Micoli KJ et al. | Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis. | 2000 | J. Biol. Chem. | pmid:10625668 |
| Allan D | Lipid metabolic changes caused by short-chain ceramides and the connection with apoptosis. | 2000 | Biochem. J. | pmid:10642519 |
| Liu J et al. | Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide. | 2000 | Am. J. Physiol., Cell Physiol. | pmid:10644522 |
| Craighead M et al. | Caspases mediate C2-ceramide-induced apoptosis of the human oligodendroglial cell line, MO3.13. | 2000 | Neurosci. Lett. | pmid:10653009 |
| Davis MA et al. | Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells. | 2000 | Toxicol. Sci. | pmid:10653520 |
| Kristal BS and Brown AM | Ganglioside GD3, the mitochondrial permeability transition, and apoptosis. | 1999 | Ann. N. Y. Acad. Sci. | pmid:10672258 |
| Salinas M et al. | Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells. | 2000 | Mol. Cell. Neurosci. | pmid:10673324 |
| Tsushima H and Mori M | In vivo evidence that activation of tyrosine kinase is a trigger for lipopolysaccharide-induced fever in rats. | 2000 | Brain Res. | pmid:10678764 |
| Mihai R et al. | C2-Ceramide increases cytoplasmic calcium concentrations in human parathyroid cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10679256 |