| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Eye Abnormalities | D005124 | 7 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Medulloblastoma | D008527 | 22 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Neuronal Ceroid-Lipofuscinoses | D009472 | 5 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Retinoblastoma | D012175 | 12 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
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|---|---|---|---|---|
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| Monney L et al. | Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis. | 1998 | Eur. J. Biochem. | pmid:9492297 |
| Maguer-Satta V et al. | BCR-ABL accelerates C2-ceramide-induced apoptosis. | 1998 | Oncogene | pmid:9464542 |
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| Lauricella M et al. | Increased cyclin E level in retinoblastoma cells during programmed cell death. | 1998 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:9874510 |
| Ibitayo AI et al. | Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle. | 1998 | Am. J. Physiol. | pmid:9756500 |
| Vento R et al. | Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide. | 1998 | Mol. Cell. Biochem. | pmid:9746206 |
| Mutoh T et al. | Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells. | 1998 | J. Biol. Chem. | pmid:9748278 |
| Rossner S et al. | p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells. | 1998 | J. Neurochem. | pmid:9681467 |
| Cartus T et al. | Distribution of protein phosphatases type 1 and 2A in RINm5F cells. | 1998 | Regul. Pept. | pmid:9809799 |
| Mizushima N et al. | Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells. | 1998 | Ann. Rheum. Dis. | pmid:9797556 |
| Birt DF et al. | Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine. | 1998 | Nutr Cancer | pmid:9770723 |
| Ji L et al. | Effects of endoglycoceramidase or D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol on glucose uptake, glycolysis, and mitochondrial respiration in HL60 cells. | 1998 | Arch. Biochem. Biophys. | pmid:9799567 |
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| Lian JP et al. | Products of sphingolipid catabolism block activation of the p21-activated protein kinases in neutrophils. | 1998 | J. Immunol. | pmid:9780215 |
| Hama-Inaba H et al. | Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation. | 1998 | Mutat. Res. | pmid:9726009 |
| Durrieu F et al. | Caspase activation is an early event in anthracycline-induced apoptosis and allows detection of apoptotic cells before they are ingested by phagocytes. | 1998 | Exp. Cell Res. | pmid:9596989 |
| Galadari S et al. | Purification and characterization of ceramide-activated protein phosphatases. | 1998 | Biochemistry | pmid:9698369 |
| Hershberger PA et al. | In vitro thymocyte maturation is associated with reduced cellular susceptibility to Fas-mediated apoptosis. | 1998 | Cell. Immunol. | pmid:9636691 |