| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
N-acetylsphingosine
N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.
Cross Reference
Introduction
To understand associated biological information of N-acetylsphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with N-acetylsphingosine?
N-acetylsphingosine is suspected in Morphologically altered structure, protrusion, DERMATITIS HERPETIFORMIS, FAMILIAL, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with N-acetylsphingosine
PubChem Associated disorders and diseases
What pathways are associated with N-acetylsphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with N-acetylsphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with N-acetylsphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with N-acetylsphingosine?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with N-acetylsphingosine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang LX et al. | [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis]. | 2007 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:18206046 |
| Huang Y et al. | [Ceramide participates in cell programmed death induced by Type II anti-CD20 mAb]. | 2015 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:26739069 |
| Li R et al. | [Effect of ceramide on GSTA1 in Caco-2 cells]. | 2012 | Yao Xue Xue Bao | pmid:22993865 |
| Zhang XF et al. | Apoptosis of human colon carcinoma HT-29 cells induced by ceramide. | 2006 | World J. Gastroenterol. | pmid:16773715 |
| Wang J et al. | Mechanisms involved in ceramide-induced cell cycle arrest in human hepatocarcinoma cells. | 2007 | World J. Gastroenterol. | pmid:17373752 |
| Zhang XF et al. | [Effect of ceramide on apoptosis of human colon cancer HT-29 cells]. | 2006 | Wei Sheng Yan Jiu | pmid:17086696 |
| Zhang X et al. | [Mitochondrial changes in apoptosis of HT-29 cells induced by C2-ceramide]. | 2008 | Wei Sheng Yan Jiu | pmid:19069652 |
| Zhang H et al. | Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation. | 2017 | Vascul. Pharmacol. | pmid:28797762 |
| Elner SG et al. | Retinal flavoprotein autofluorescence as a measure of retinal health. | 2008 | Trans Am Ophthalmol Soc | pmid:19277237 |
| Davis MA et al. | Effect of ceramide on intracellular glutathione determines apoptotic or necrotic cell death of JB6 tumor cells. | 2000 | Toxicol. Sci. | pmid:10653520 |