1-octacosanol

1-octacosanol is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 353 references associated with 1-octacosanol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 1-octacosanol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1-octacosanol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Total 4

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 1-octacosanol

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Authors Title Published Journal PubMed Link
Giuffrè AM and Capocasale M Policosanol in Tomato (Solanum lycopersicum L.) Seed Oil: the Effect of Cultivar. 2015 J Oleo Sci pmid:25891114
Ramasamy D and Saraswathy A Vitiquinolone--a quinolone alkaloid from Hibiscus vitifolius Linn. 2014 Food Chem pmid:24128571
Myung K et al. Interaction of organic solvents with the epicuticular wax layer of wheat leaves. 2013 J. Agric. Food Chem. pmid:23964787
Martínez-Sánchez G et al. Effects of ozone therapy on haemostatic and oxidative stress index in coronary artery disease. 2012 Eur. J. Pharmacol. pmid:22796450
Sashidhara KV et al. Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi. 2012 Eur J Med Chem pmid:22348826
Yang P et al. Transcriptome analysis of the Chinese white wax scale Ericerus pela with focus on genes involved in wax biosynthesis. 2012 PLoS ONE pmid:22536429
de Oliveira AM et al. Antinociceptive and anti-inflammatory effects of octacosanol from the leaves of Sabicea grisea var. grisea in mice. 2012 Int J Mol Sci pmid:22408410
Ravinayagam V et al. Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B(1)-Induced Experimental Hepatocellular Carcinoma. 2012 Int J Hepatol pmid:22518320
Luo Z et al. Protective effect of theaflavins on neuron against 6-hydroxydopamine-induced apoptosis in SH-SY5Y cells. 2012 J Clin Biochem Nutr pmid:22448094
Nariya PB et al. Antimicrobial and antifungal activities of Cordia dichotoma (Forster F.) bark extracts. 2011 Ayu pmid:22661859
Liu W et al. Multiple plant surface signals are sensed by different mechanisms in the rice blast fungus for appressorium formation. 2011 PLoS Pathog. pmid:21283781
Thulin E et al. Molecular determinants of S100B oligomer formation. 2011 PLoS ONE pmid:21445240
Jung DM et al. A gas chromatography-tandem quadrupole mass spectrometric analysis of policosanols in commercial vegetable oils. 2011 J. Food Sci. pmid:22417487
Jones AM et al. A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 27. 2011 Br J Sports Med pmid:22076991
Ebert B et al. Metabolic profiling of Arabidopsis thaliana epidermal cells. 2010 J. Exp. Bot. pmid:20150518
Maruthappan V and Shree KS Effects of Phyllanthus reticulatus on lipid profile and oxidative stress in hypercholesterolemic albino rats. 2010 Indian J Pharmacol pmid:21189912
Villaflores OB et al. Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis. 2010 Pharmacogn Mag pmid:21120040
Kunwar RM et al. Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. 2010 J Ethnobiol Ethnomed pmid:21144003
Chandrasekar SB et al. Phytopharmacology of Ficus religiosa. 2010 Pharmacogn Rev pmid:22228961
Broz AK et al. Plant neighbor identity influences plant biochemistry and physiology related to defense. 2010 BMC Plant Biol. pmid:20565801
Cravotto G et al. Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin. 2010 Nat. Prod. Res. pmid:20306365
Wang T et al. Protective effects of octacosanol on 6-hydroxydopamine-induced Parkinsonism in rats via regulation of ProNGF and NGF signaling. 2010 Acta Pharmacol. Sin. pmid:20581854
Okabe T et al. Antiatherosclerotic function of Kokuto, Okinawan noncentrifugal cane sugar. 2009 J. Agric. Food Chem. pmid:19072226
Fernández-Arche A et al. Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. 2009 J. Nutr. Biochem. pmid:18555679
Mukherjee S et al. Solid lipid nanoparticles: a modern formulation approach in drug delivery system. 2009 Indian J Pharm Sci pmid:20502539
Lytovchenko A et al. Application of GC-MS for the detection of lipophilic compounds in diverse plant tissues. 2009 Plant Methods pmid:19393072
Oliaro-Bosso S et al. Regulation of HMGCoA reductase activity by policosanol and octacosadienol, a new synthetic analogue of octacosanol. 2009 Lipids pmid:19763655
Haim D et al. Trace quantification of 1-octacosanol and 1-triacontanol and their main metabolites in plasma by liquid-liquid extraction coupled with gas chromatography-mass spectrometry. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19931494
Arvidson KB et al. In silico toxicological screening of natural products. 2008 Toxicol. Mech. Methods pmid:20020917
Ohta Y et al. Octacosanol attenuates disrupted hepatic reactive oxygen species metabolism associated with acute liver injury progression in rats intoxicated with carbon tetrachloride. 2008 J Clin Biochem Nutr pmid:18385828
Dullens SP et al. Effects of emulsified policosanols with different chain lengths on cholesterol metabolism in heterozygous LDL receptor-deficient mice. 2008 J. Lipid Res. pmid:18162663
Keller S et al. Octacosanol administration to humans decreases neutral sterol and bile acid concentration in feces. 2008 Lipids pmid:18004604
Kassis AN and Jones PJ Changes in cholesterol kinetics following sugar cane policosanol supplementation: a randomized control trial. 2008 Lipids Health Dis pmid:18447941
Thippeswamy G et al. Octacosanol isolated from Tinospora cordifolia downregulates VEGF gene expression by inhibiting nuclear translocation of NF-<kappa>B and its DNA binding activity. 2008 Eur. J. Pharmacol. pmid:18513715
Yang XY et al. [Effect of octacostyl alcohol preparation on blood free radical metabolism and cardiac endocrine function of rats]. 2008 Nan Fang Yi Ke Da Xue Xue Bao pmid:18495613
Nasri N et al. Quantification of sterols and aliphatic alcohols in Mediterranean stone pine (Pinus pinea L.) populations. 2007 J. Agric. Food Chem. pmid:17309279
Marinangeli CP et al. Comparison of composition and absorption of sugarcane policosanols. 2007 Br. J. Nutr. pmid:17298709
Zhang X et al. [Study on the active components of Nardostachys chinensis]. 2007 Zhong Yao Cai pmid:17539300
Kassis AN et al. Lack of effect of sugar cane policosanol on plasma cholesterol in Golden Syrian hamsters. 2007 Atherosclerosis pmid:17123537
Singh DK et al. Policosanol inhibits cholesterol synthesis in hepatoma cells by activation of AMP-kinase. 2006 J. Pharmacol. Exp. Ther. pmid:16714400
Calvo Romero JM and Lima Rodríguez EM ["Natural" treatments of hypercholesterolemia]. 2006 Rev Clin Esp pmid:17129518
Koch K et al. Structural analysis of wheat wax (Triticum aestivum, c.v. 'Naturastar' L.): from the molecular level to three dimensional crystals. 2006 Planta pmid:16133211
Menéndez R et al. In vitro and in vivo study of octacosanol metabolism. 2005 Mar-Apr Arch. Med. Res. pmid:15847942
Ng CH et al. Policosanol has no antioxidant activity in human low-density lipoprotein but increases excretion of bile acids in hamsters. 2005 J. Agric. Food Chem. pmid:16076108
Gniwotta F et al. What do microbes encounter at the plant surface? Chemical composition of pea leaf cuticular waxes. 2005 Plant Physiol. pmid:16113231
Nash D et al. Quantitative determination of sterols and other alcohols in overland flow from grazing land and possible source materials. 2005 Water Res. pmid:15998530
Cicero AF et al. Antihyperlipidaemic effect of a Monascus purpureus brand dietary supplement on a large sample of subjects at low risk for cardiovascular disease: a pilot study. 2005 Complement Ther Med pmid:16338198
Lin Y et al. Wheat germ policosanol failed to lower plasma cholesterol in subjects with normal to mildly elevated cholesterol concentrations. 2004 Metab. Clin. Exp. pmid:15375787
Lü TS et al. [A new chromone glycoside from Cassia siamea lam]. 2003 Yao Xue Xue Bao pmid:12778745
Taylor JC et al. Octacosanol in human health. 2003 Nutrition pmid:12591561