| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
Total
1
Falcarindiol
Falcarindiol is a lipid of Fatty Acyls (FA) class. Falcarindiol is associated with abnormalities such as Contact Dermatitis and Immune System Diseases. The involved functions are known as Delayed Hypersensitivity, Immune Tolerance, Stimulus, Metabolic Inhibition and Biochemical Pathway. Falcarindiol often locates in Cell surface, Abdomen and Bone Marrow. The associated genes with Falcarindiol are CD276 Antigen, VTCN1 gene, RELB gene, L1RE1 gene and ICOSLG gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Falcarindiol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Falcarindiol?
Falcarindiol is suspected in Contact Dermatitis, Immune System Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Falcarindiol
PubChem Associated disorders and diseases
What pathways are associated with Falcarindiol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Falcarindiol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Falcarindiol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Falcarindiol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Falcarindiol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Falcarindiol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Falcarindiol?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Falcarindiol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lu T et al. | Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress. | 2017 | PLoS ONE | pmid:28441457 |
| Liu G et al. | Identification of Nematicidal Constituents of Notopterygium incisum Rhizomes against Bursaphelenchus xylophilus and Meloidogyne incognita. | 2016 | Molecules | pmid:27669203 |
| Wang L et al. | Total Synthesis of Chiral Falcarindiol Analogues Using BINOL-Promoted Alkyne Addition to Aldehydes. | 2016 | Molecules | pmid:26797597 |
| Aguiló-Aguayo I et al. | Exploring the effects of pulsed electric field processing parameters on polyacetylene extraction from carrot slices. | 2015 | Molecules | pmid:25738537 |
| Uto T et al. | Anti-inflammatory Activity of Constituents Isolated from Aerial Part of Angelica acutiloba Kitagawa. | 2015 | Phytother Res | pmid:26463105 |
| Liu X et al. | Polyyne hybrid compounds from Notopterygium incisum with peroxisome proliferator-activated receptor gamma agonistic effects. | 2014 | J. Nat. Prod. | pmid:25333853 |
| Guzman JD et al. | Antimycobacterials from lovage root (Ligusticum officinale Koch). | 2013 | Phytother Res | pmid:22899555 |
| Seljåsen R et al. | Influence of field attack by carrot psyllid (Trioza apicalis Förster) on sensory quality, antioxidant capacity and content of terpenes, falcarindiol and 6-methoxymellein of carrots (Daucus carota L.). | 2013 | J. Agric. Food Chem. | pmid:23414489 |
| Atanasov AG et al. | Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gamma. | 2013 | PLoS ONE | pmid:23630612 |
| Wang CZ et al. | Identification of potential anticancer compounds from Oplopanax horridus. | 2013 | Phytomedicine | pmid:23746754 |
| Yoshida J et al. | Inhibition of glycogen synthase kinase-3β by falcarindiol isolated from Japanese Parsley (Oenanthe javanica). | 2013 | J. Agric. Food Chem. | pmid:23895038 |
| Jin HR et al. | The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress. | 2012 | Cell Death Dis | pmid:22914324 |
| Kjellenberg L et al. | Polyacetylenes in fresh and stored carrots (Daucus carota): relations to root morphology and sugar content. | 2012 | J. Sci. Food Agric. | pmid:22190221 |
| Wyrembek P et al. | Falcarindiol allosterically modulates GABAergic currents in cultured rat hippocampal neurons. | 2012 | J. Nat. Prod. | pmid:22432736 |
| Su X et al. | [Fingerprint analysis of Glehniae Radix by TLC]. | 2012 | Zhong Yao Cai | pmid:22822664 |
| Ohnuma T et al. | Dietary diacetylene falcarindiol induces phase 2 drug-metabolizing enzymes and blocks carbon tetrachloride-induced hepatotoxicity in mice through suppression of lipid peroxidation. | 2011 | Biol. Pharm. Bull. | pmid:21372387 |
| Chung IM et al. | Anticomplement activity of polyacetylenes from leaves of Dendropanax morbifera Leveille. | 2011 | Phytother Res | pmid:21520473 |
| Roman M et al. | Spectroscopic studies on bioactive polyacetylenes and other plant components in wild carrot root. | 2011 | J. Nat. Prod. | pmid:21800857 |
| Rai DK et al. | Characterisation of polyacetylenes isolated from carrot (Daucus carota) extracts by negative ion tandem mass spectrometry. | 2011 | Rapid Commun. Mass Spectrom. | pmid:21735506 |
| Bae KE et al. | Components of rhizome extract of Cnidium officinale Makino and their in vitro biological effects. | 2011 | Molecules | pmid:22019572 |
| Mitsui S et al. | The herbal medicine compound falcarindiol from Notopterygii Rhizoma suppresses dendritic cell maturation. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20215408 |
| Meot-Duros L et al. | New antibacterial and cytotoxic activities of falcarindiol isolated in Crithmum maritimum L. leaf extract. | 2010 | Food Chem. Toxicol. | pmid:19922760 |
| Vucković I et al. | A new prenylated flavanonol from Seseli annuum roots showing protective effect on human lymphocytes DNA. | 2010 | Chem. Biodivers. | pmid:20232332 |
| Wang J et al. | [Fast determination of active components in Angelica dahurica extract using capillary electrochromatography with methacrylate ester-based monolithic columns]. | 2010 | Se Pu | pmid:20549974 |
| Ohnuma T et al. | Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound. | 2010 | Toxicol. Appl. Pharmacol. | pmid:20026152 |
| Purup S et al. | Differential effects of falcarinol and related aliphatic C(17)-polyacetylenes on intestinal cell proliferation. | 2009 | J. Agric. Food Chem. | pmid:19694436 |
| Ohnuma T et al. | Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress. | 2009 | Arch. Biochem. Biophys. | pmid:19527678 |
| Schmiech L et al. | Structure determination of bisacetylenic oxylipins in carrots (Daucus carota L.) and enantioselective synthesis of falcarindiol. | 2009 | J. Agric. Food Chem. | pmid:19845355 |
| Ma Z et al. | Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors. | 2008 | Bioorg. Med. Chem. | pmid:18166466 |
| Schinkovitz A et al. | Antimycobacterial polyacetylenes from Levisticum officinale. | 2008 | Phytother Res | pmid:18350523 |
| Prior RM et al. | The polyacetylene falcarindiol with COX-1 activity isolated from Aegopodium podagraria L. | 2007 | J Ethnopharmacol | pmid:17574359 |
| Wang YL et al. | LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui. | 2005 | Anal Bioanal Chem | pmid:16132135 |
| Shiao YJ et al. | Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes. | 2005 | Br. J. Pharmacol. | pmid:15644867 |
| Stavri M and Gibbons S | The antimycobacterial constituents of dill (Anethum graveolens). | 2005 | Phytother Res | pmid:16317649 |
| Stavri M et al. | New constituents of Artemisia monosperma. | 2004 | J. Nat. Prod. | pmid:15165159 |
| Czepa A and Hofmann T | Quantitative studies and sensory analyses on the influence of cultivar, spatial tissue distribution, and industrial processing on the bitter off-taste of carrots (Daucus carota l.) and carrot products. | 2004 | J. Agric. Food Chem. | pmid:15237959 |
| Lechner D et al. | The anti-staphylococcal activity of Angelica dahurica (Bai Zhi). | 2004 | Phytochemistry | pmid:14751304 |
| Czepa A and Hofmann T | Structural and sensory characterization of compounds contributing to the bitter off-taste of carrots (Daucus carota L.) and carrot puree. | 2003 | J. Agric. Food Chem. | pmid:12797757 |
| Kim JM et al. | Falcarindiol inhibits nitric oxide-mediated neuronal death in lipopolysaccharide-treated organotypic hippocampal cultures. | 2003 | Neuroreport | pmid:14561925 |
| Ratnayake AS and Hemscheidt T | Olefin cross-metathesis as a tool in natural product degradation. The stereochemistry of (+)-falcarindiol. | 2002 | Org. Lett. | pmid:12489956 |
| Setzer WN et al. | Synthesis and cytotoxic activity of a series of diacetylenic compounds related to falcarindiol. | 2000 | Chem. Pharm. Bull. | pmid:11086913 |
| Nakano Y et al. | Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii. | 1998 | Biol. Pharm. Bull. | pmid:9556156 |
| Furumi K et al. | Novel antiproliferative falcarindiol furanocoumarin ethers from the root of Angelica japonica. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871635 |
| Matsuda H et al. | Hepatoprotective and nitric oxide production inhibitory activities of coumarin and polyacetylene constituents from the roots of Angelica furcijuga. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873511 |
| Liu JH et al. | Inhibitory effects of Angelica pubescens f. biserrata on 5-lipoxygenase and cyclooxygenase. | 1998 | Planta Med. | pmid:9741298 |
| Rao G et al. | [Polyacetylene compounds from Panax notoginsenoside]. | 1997 | Zhong Yao Cai | pmid:12572474 |
| Satoh A et al. | Potent allelochemical falcalindiol from Glehnia littoralis F. Schm. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8824837 |
| Cunsolo F et al. | Bioactive metabolites from Sicilian marine fennel, Crithmum maritimum. | 1993 | J. Nat. Prod. | pmid:8254353 |
| Villegas M et al. | Isolation of the antifungal compounds falcarindiol and sarisan from Heteromorpha trifoliata. | 1988 | Planta Med. | pmid:3375335 |
| Muir AD et al. | Antibiotic compounds from New Zealand plants. I. Falcarindiol, an anti-dermatophyte agent from Schefflera digitata. | 1982 | Planta Med. | pmid:7089093 |
| pmid: | ||||
| pmid:28197615 | ||||
| pmid:27667518 | ||||
| pmid:26886865 | ||||
| pmid:25474700 |