octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Nakajima K et al. Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. 2016 Biomed. Res. pmid:28003581
Hogan S et al. Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. 2016 Antimicrob. Agents Chemother. pmid:27458213
Lockman KA et al. Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. 2016 Lipids Health Dis pmid:27368608
Rodríguez-Moyá M and Gonzalez R Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. 2015 J Proteomics pmid:25845584
Chen Y et al. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. 2015 Int J Pharm pmid:25841571
Damitz R and Chauhan A Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. 2015 Int J Pharm pmid:25839419
Royce LA et al. Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity. 2015 Metab. Eng. pmid:25839166
Oiso S et al. Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. 2015 J Oleo Sci pmid:26521811
Fredrickson J et al. The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model. 2015 J. Assist. Reprod. Genet. pmid:26342329
Xu J et al. In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. 2015 Chem. Commun. (Camb.) pmid:25792085