octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Snake Bites D012909 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chickenpox D002644 1 associated lipids
Essential Tremor D020329 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Miller TB Cardiac performance of isolated perfused hearts from alloxan diabetic rats. 1979 Am. J. Physiol. pmid:443443
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Patel TB Effect of sulfonylureas on hepatic fatty acid oxidation. 1986 Am. J. Physiol. pmid:3090894
Maes BD et al. Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. 1998 Am. J. Physiol. pmid:9655697
Sidossis LS et al. Regulation of fatty acid oxidation in untrained vs. trained men during exercise. 1998 Am. J. Physiol. pmid:9530135
Chen TM et al. Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. 1997 Am. J. Physiol. pmid:9374750
Adams SH and Odle J Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. 1993 Am. J. Physiol. pmid:8238444
Morand C et al. Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. 1993 Am. J. Physiol. pmid:8498503
Werner JC et al. Fatty acid and glucose utilization in isolated, working newborn pig hearts. 1983 Am. J. Physiol. pmid:6849379
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
REICH WJ et al. The treatment of monilial vaginitis with caprylic acid. 1953 Am. J. Obstet. Gynecol. pmid:13016687
Talley NJ et al. Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? 2001 Am. J. Gastroenterol. pmid:11374677
Vanheel H et al. Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. 2017 Am. J. Gastroenterol. pmid:27958284
Lee JS et al. Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. 2000 Am. J. Gastroenterol. pmid:11051344
Cappello G et al. Gastric emptying of a solid-liquid meal measured with 13C octanoic acid breath test and real-time ultrasonography: a comparative study. 2000 Am. J. Gastroenterol. pmid:11095323
Rabinowitz JL et al. The effects of intravenous sodium octanoate on the rhesus monkey. 1978 Am. J. Gastroenterol. pmid:96693
Choi MG et al. Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. 1998 Am. J. Gastroenterol. pmid:9448183
Miele L et al. Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test. 2003 Am. J. Gastroenterol. pmid:14572600
Perri F et al. Patterns of symptoms in functional dyspepsia: role of Helicobacter pylori infection and delayed gastric emptying. 1998 Am. J. Gastroenterol. pmid:9820377