| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cheng Y et al. | Thermally controlled release of anticancer drug from self-assembled γ-substituted amphiphilic poly(ε-caprolactone) micellar nanoparticles. | 2012 | Biomacromolecules | pmid:22681332 |
| Haynes D et al. | In situ copolyesters containing poly(L-lactide) and poly(hydroxyalkanoate) units. | 2007 | Biomacromolecules | pmid:17371065 |
| Hu Y et al. | Degradation behavior of poly(epsilon-caprolactone)-b-poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles in aqueous solution. | Biomacromolecules | pmid:15360284 | |
| Barnette D et al. | Pathogen safety profile of a 10% IgG preparation manufactured using a depth filtration-modified process. | 2012 | Biologicals | pmid:22579294 |
| Solano S et al. | Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. | 2012 | Biologicals | pmid:22266304 |
| Johnston A et al. | Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. | 2003 | Biologicals | pmid:12935811 |
| Estrada R et al. | Intravenous administration of equine-derived whole IgG antivenom does not induce early adverse reactions in non-envenomed horses and cows. | 2010 | Biologicals | pmid:20833066 |
| Segura A et al. | Assessment of the impact of solvent/detergent treatment on the quality and potency of a whole IgG equine antivenom. | 2009 | Biologicals | pmid:19540775 |
| Stucki M et al. | Investigations of prion and virus safety of a new liquid IVIG product. | 2008 | Biologicals | pmid:18337119 |
| Mpandi M et al. | Partitioning and inactivation of viruses by the caprylic acid precipitation followed by a terminal pasteurization in the manufacturing process of horse immunoglobulins. | 2007 | Biologicals | pmid:17470396 |
| Burnouf T et al. | Assessment of viral inactivation during pH 3.3 pepsin digestion and caprylic acid treatment of antivenoms. | 2007 | Biologicals | pmid:17363271 |
| Simsiriwong P et al. | A study on the use of caprylic acid and ammonium sulfate in combination for the fractionation of equine antivenom F(ab')(2). | 2012 | Biologicals | pmid:22704919 |
| Burnouf T et al. | Assessment of the viral safety of antivenoms fractionated from equine plasma. | 2004 | Biologicals | pmid:15536042 |
| Herrera M et al. | Development and validation of a reverse phase HPLC method for the determination of caprylic acid in formulations of therapeutic immunoglobulins and its application to antivenom production. | 2009 | Biologicals | pmid:19375941 |
| Athavale M et al. | Validation of a simple, rapid and cost effective method for the estimation of caprylic acid and sodium caprylate from biological products using NEFA-C kit. | 2010 | Biologicals | pmid:19919899 |
| GarcÃa M et al. | Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. | 2002 | Biologicals | pmid:12127316 |
| Korneyeva M et al. | Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates. | 2002 | Biologicals | pmid:12127317 |
| Dichtelmüller H et al. | Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. | 2002 | Biologicals | pmid:12127315 |
| Kuge Y et al. | [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. | 2000 | Biol. Pharm. Bull. | pmid:10963308 |
| Tokudome Y and Otsuka M | Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. | 2012 | Biol. Pharm. Bull. | pmid:22975500 |
| Uchida M and Shimizu K | 13C-acetic acid is more sensitive than 13C-octanoic acid for evaluating gastric emptying of liquid enteral nutrient formula by breath test in conscious rats. | 2007 | Biol. Pharm. Bull. | pmid:17329843 |
| Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
| Lemmen C et al. | Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts. | 1988 | Biol. Chem. Hoppe-Seyler | pmid:3242549 |
| Küster J et al. | Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. | 1989 | Biol. Chem. Hoppe-Seyler | pmid:2692615 |
| Kundu S and Roy D | Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. | 2010 | Bioinformation | pmid:20978606 |
| Kumar S | Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. | 2011 | Bioinformation | pmid:22355237 |
| Nagata J et al. | Effects of structured lipids containing eicosapentaenoic or docosahexaenoic acid and caprylic acid on serum and liver lipid profiles in rats. | 2004 | Biofactors | pmid:15630273 |
| Goussen C et al. | Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. | 2017 | BioDrugs | pmid:28508264 |
| van Ginkel CG et al. | Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. | 2008 | Biodegradation | pmid:17492358 |
| Pochapsky SS et al. | Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. | 1990 Jul-Aug | Bioconjug. Chem. | pmid:2096916 |
| Salesse R et al. | [Intensity and anisotropy decays measurement of perylene in pigeon erythrocyte membrane. Comparison with an isotropic viscous medium (author's transl)]. | 1981 Nov-Dec | Biochimie | pmid:7332761 |
| Pérez-Diaz J et al. | Preparation and metabolic characterization of isolated rat lung cells. | 1977 | Biochimie | pmid:195638 |
| Mannaerts GP et al. | Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. | 1978 | Biochim. Biophys. Acta | pmid:656451 |
| Nieuwenhuizen W et al. | Purification and properties of two lipases from pig adipose tissue. | 1976 | Biochim. Biophys. Acta | pmid:7300 |
| MartÃnez Izquierdo JA et al. | Fatty acid-glucose interaction in the control of protein synthesis by isolated rat lung cells. | 1983 | Biochim. Biophys. Acta | pmid:6615881 |
| Merrill AR et al. | Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. | 1986 | Biochim. Biophys. Acta | pmid:3081028 |
| Veerkamp JH et al. | An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. | 1986 | Biochim. Biophys. Acta | pmid:3081042 |
| McDonough KH et al. | Effects of oxygen radicals on substrate oxidation by cardiac myocytes. | 1987 | Biochim. Biophys. Acta | pmid:2822138 |
| Groot PH and Hülsmann WC | The activation and oxidation of octanoate and palmitate by rat skeletal muscle mitochondria. | 1973 | Biochim. Biophys. Acta | pmid:4741907 |
| Barron JT et al. | Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. | 1997 | Biochim. Biophys. Acta | pmid:9452767 |
| Murphy MG et al. | Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy. | 1996 | Biochim. Biophys. Acta | pmid:8611661 |
| Yon JO et al. | Incorporation of extracellular phospholipids and their effect on the growth and lipid metabolism of the Saccharomyces cerevisiae cho1/pss mutant. | 1998 | Biochim. Biophys. Acta | pmid:9767089 |
| Kato T et al. | Short- and medium-chain fatty acids enhance the cell surface expression and transport capacity of the bile salt export pump (BSEP/ABCB11). | 2010 | Biochim. Biophys. Acta | pmid:20398791 |
| Wanders RJ and Ijlst L | Fatty acid beta-oxidation in leukocytes from control subjects and medium-chain acyl-CoA dehydrogenase deficient patients. | 1992 | Biochim. Biophys. Acta | pmid:1737072 |
| Matsuki H et al. | Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate. | 1999 | Biochim. Biophys. Acta | pmid:9878713 |
| Stace PB et al. | Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. | 1992 | Biochim. Biophys. Acta | pmid:1319745 |
| Hinson JA and Neal RA | An examination of octanol and octanal metabolism to octanoic acid by horse liver alcohol dehydrogenase. | 1975 | Biochim. Biophys. Acta | pmid:165828 |
| Apel CL et al. | Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers. | 2002 | Biochim. Biophys. Acta | pmid:11825583 |
| González-Manchón C et al. | Ca2(+)-fatty acid interaction in the control of hepatic gluconeogenesis. | 1990 | Biochim. Biophys. Acta | pmid:2310772 |
| Nomura T et al. | Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. | 1983 | Biochim. Biophys. Acta | pmid:6317044 |