octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mao LF et al. | Hepatic beta-oxidation of 3-phenylpropionic acid and the stereospecific dehydration of (R)- and (S)-3-hydroxy-3-phenylpropionyl-CoA by different enoyl-CoA hydratases. | 1994 | Biochemistry | pmid:8136368 |
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Mitkov D | The role of the octanoic fatty acid in the pathogenesis of the metabolic alkalosis in experimental liver failure. | 1993 | Folia Med (Plovdiv) | pmid:8194797 |
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Morris TW et al. | Identification of the gene encoding lipoate-protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene product. | 1994 | J. Biol. Chem. | pmid:8206909 |
Massolini G et al. | Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases. | 1993 | Biochem. Pharmacol. | pmid:8216380 |
Alvarez CV et al. | Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells. | 1993 | Neuroendocrinology | pmid:8232763 |
Adams SH and Odle J | Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. | 1993 | Am. J. Physiol. | pmid:8238444 |
MartÃn-Requero A et al. | Reciprocal changes in gluconeogenesis and ureagenesis induced by fatty acid oxidation. | 1993 | Metab. Clin. Exp. | pmid:8246772 |
Guimbretiere J et al. | [A further case of albumin auto-agglutination in a blood donor]. | 1976 | Rev. Fr. Transfus. Immunohematol. | pmid:824703 |
Dieuaide M et al. | Effects of glucose starvation on the oxidation of fatty acids by maize root tip mitochondria and peroxisomes: evidence for mitochondrial fatty acid beta-oxidation and acyl-CoA dehydrogenase activity in a higher plant. | 1993 | Biochem. J. | pmid:8250843 |
Odle J et al. | Emulsification and fatty acid chain length affect the kinetics of [14C]-medium-chain triacylglycerol utilization by neonatal piglets. | 1994 | J. Nutr. | pmid:8283298 |
Viegas CA et al. | Regulation of the expression of the H(+)-ATPase genes PMA1 and PMA2 during growth and effects of octanoic acid in Saccharomyces cerevisiae. | 1994 | Biochim. Biophys. Acta | pmid:8286419 |
Fitzsimmons ME and Anders MW | Fatty acid beta-oxidation-dependent bioactivation of halogenated thiaalkanoic acids in isolated rat hepatocytes. | 1993 Sep-Oct | Chem. Res. Toxicol. | pmid:8292744 |
Hulsmann WC et al. | Imminent ischemia in normal and hypertrophic Langendorff rat hearts; effects of fatty acids and superoxide dismutase monitored by NADH surface fluorescence. | 1993 | Biochim. Biophys. Acta | pmid:8318552 |
Wieland TM et al. | Utilization of medium-chain triglycerides by neonatal pigs: effects of emulsification and dose delivered. | 1993 | J. Anim. Sci. | pmid:8349513 |