octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Chickenpox D002644 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chylothorax D002916 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Flatulence D005414 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Essential Tremor D020329 2 associated lipids
Gastroparesis D018589 2 associated lipids
Prion Diseases D017096 2 associated lipids
Giardiasis D005873 3 associated lipids
Malocclusion D008310 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Gallstones D042882 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Coccidiosis D003048 3 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Reye Syndrome D012202 14 associated lipids
Hemorrhage D006470 15 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Endotoxemia D019446 27 associated lipids
Kidney Diseases D007674 29 associated lipids
Obesity D009765 29 associated lipids
Hypothyroidism D007037 32 associated lipids
Diarrhea D003967 32 associated lipids
Memory Disorders D008569 33 associated lipids
Epilepsy D004827 35 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Starvation D013217 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Insulin Resistance D007333 99 associated lipids
Glioma D005910 112 associated lipids
Inflammation D007249 119 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Ishii-Iwamoto EL et al. Effects of norepinephrine on the metabolism of fatty acids with different chain lengths in the perfused rat liver. 2000 Mol. Cell. Biochem. pmid:10821418
Awan MM et al. Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart. 2000 Mol. Cell. Biochem. pmid:11055554
Pantazaki AA et al. Polyhydroxyalkanoate (PHA) biosynthesis in Thermus thermophilus: purification and biochemical properties of PHA synthase. 2003 Mol. Cell. Biochem. pmid:14674696
Abdel-aleem S et al. Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia. 1998 Mol. Cell. Biochem. pmid:9546635
Scaini G et al. Toxicity of octanoate and decanoate in rat peripheral tissues: evidence of bioenergetic dysfunction and oxidative damage induction in liver and skeletal muscle. 2012 Mol. Cell. Biochem. pmid:22015654
Leverve X et al. Oxidative phosphorylation in intact hepatocytes: quantitative characterization of the mechanisms of change in efficiency and cellular consequences. 1998 Mol. Cell. Biochem. pmid:9746312
Elliott KR and Pogson CI Preparation and characterization of isolated parenchymal cells from guinea pig liver. 1977 Mol. Cell. Biochem. pmid:196181
Tissier C et al. Substrate dependence of the postischemic cardiomyocyte recovery: dissociation between functional, metabolic and injury markers. 2005 Mol. Cell. Biochem. pmid:16013439
Coort SL et al. Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake. 2002 Mol. Cell. Biochem. pmid:12479588
Salesse R and Garnier J Adenylate cyclase and membrane fluidity. The repressor hypothesis. 1984 Mol. Cell. Biochem. pmid:6323963
McNamara BC and Jefcoate CR Heterogeneous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from ACTH-treated rats: differential responses to different reducing precursors. 1990 Mol. Cell. Endocrinol. pmid:2176627
Seydoux J et al. Impaired metabolic response to nerve stimulation in brown adipose tissue of hypothyroid rats. 1982 Mol. Cell. Endocrinol. pmid:6276252
Andrade López JM et al. Genetic basis of octanoic acid resistance in Drosophila sechellia: functional analysis of a fine-mapped region. 2017 Mol. Ecol. pmid:28035709
Gurvitz A The essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2. 2009 Mol. Genet. Genomics pmid:19685079
Velázquez-Arellano A et al. Functional and metabolic implications of biotin deficiency for the rat heart. 2008 Mol. Genet. Metab. pmid:18824381
Jones PM et al. Effects of odd-numbered medium-chain fatty acids on the accumulation of long-chain 3-hydroxy-fatty acids in long-chain L-3-hydroxyacyl CoA dehydrogenase and mitochondrial trifunctional protein deficient skin fibroblasts. 2004 Mol. Genet. Metab. pmid:14741189
Bokhout BA et al. Porcine IgG. Isolation of two IgG-subclasses and anti-IgG class- and subclass-specific antibodies. 1986 Mol. Immunol. pmid:2427943
Guler JL et al. Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei. 2008 Mol. Microbiol. pmid:18221265
Campbell JW et al. A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic beta-oxidation pathway. 2003 Mol. Microbiol. pmid:12535077
Ali ST et al. Octanoylation of the lipoyl domains of the pyruvate dehydrogenase complex in a lipoyl-deficient strain of Escherichia coli. 1990 Mol. Microbiol. pmid:2215217
Kursu VA et al. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. 2013 Mol. Microbiol. pmid:24102902
Montazeri Aliabadi H et al. Induction of apoptosis by survivin silencing through siRNA delivery in a human breast cancer cell line. 2011 Mol. Pharm. pmid:21838308
Meisner H and Neet K Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. 1978 Mol. Pharmacol. pmid:642932
Lohse MJ et al. Effects of temperature and membrane phase transitions on ligand binding to alpha 2-receptors of human platelets. 1986 Mol. Pharmacol. pmid:3005830
Martin FP et al. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model. 2008 Mol. Syst. Biol. pmid:18628745
Formisano C et al. Headspace volatile composition of the flowers of Caralluma europaea N.E.Br. (Apocynaceae). 2009 Molecules pmid:19924088
Sobczak M and Kolodziejski W Polymerization of cyclic esters initiated by carnitine and tin (II) octoate. 2009 Molecules pmid:19214152
Sobczak M et al. Synthesis and structural analysis of polyester prodrugs of norfloxacin. 2008 Molecules pmid:18259133
Müller T et al. Entacapone improves absorption of a coadministered salt in patients with Parkinson's disease. 2008 Mov. Disord. pmid:18546331
Unger MM et al. Patients with idiopathic rapid-eye-movement sleep behavior disorder show normal gastric motility assessed by the 13C-octanoate breath test. 2011 Mov. Disord. pmid:22147682
Liu S et al. Biological control of phytopathogenic fungi by fatty acids. 2008 Mycopathologia pmid:18443921
Lord JC and Howard RW A proposed role for the cuticular fatty amides of Liposcelis bostrychophila (Psocoptera: Liposcelidae) in preventing adhesion of entomopathogenic fungi with dry-conidia. 2004 Mycopathologia pmid:15518350
Andrén-Sandberg A Pancreatic cancer: chemotherapy and radiotherapy. 2011 N Am J Med Sci pmid:22540056
Guthy E Enteric-coated fish oil in Crohn's disease. 1996 N. Engl. J. Med. pmid:8927072
Riecken EO [Structural and functional findings in experimental blind loop syndrome]. 1984 Nahrung pmid:6493325
Shahmoradi B et al. Modification of neodymium-doped ZnO hybrid nanoparticles under mild hydrothermal conditions. 2010 Nanoscale pmid:20648343
Ma Y et al. Nanoparticles of Poly(Lactide-Co-Glycolide)-d-a-Tocopheryl Polyethylene Glycol 1000 Succinate Random Copolymer for Cancer Treatment. 2010 Nanoscale Res Lett pmid:20596457
Mei L et al. A Novel Docetaxel-Loaded Poly (ε-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment. 2009 Nanoscale Res Lett pmid:20652101
Liu JH et al. The fabrication of polycrystalline silver nanowires via self-assembled nanotubes at controlled temperature. 2009 Nanotechnology pmid:19417290
Balaraman E et al. Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. 2013 Nat Chem pmid:23344447
Andersen JT et al. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. 2012 Nat Commun pmid:22215085
Cordier C et al. Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. 2008 Nat Prod Rep pmid:18663392
Chhatre S et al. Purification of antibodies using the synthetic affinity ligand absorbent MAbsorbent A2P. 2007 Nat Protoc pmid:17641643
Abadi G et al. Naturally occurring esterification reactions with bryostatin. 2008 Nat. Prod. Res. pmid:18626821
Nazzi F et al. Octanoic acid confers to royal jelly varroa-repellent properties. 2009 Naturwissenschaften pmid:19050844
Sarnatskaya VV et al. Extraction of uraemic toxins with activated carbon restores the functional properties of albumin. 2003 Nephron Physiol pmid:14520007
Norenberg MD The role of astrocytes in hepatic encephalopathy. 1987 Feb-Apr Neurochem Pathol pmid:3306480
Schuck PF et al. Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain. 2009 Neurochem. Int. pmid:19428797
de Assis DR et al. Evidence that antioxidants prevent the inhibition of Na+,K(+)-ATPase activity induced by octanoic acid in rat cerebral cortex in vitro. 2003 Neurochem. Res. pmid:12892042
Ninomiya Y and Kayama Y Inhibition of choline acetyltransferase activity by serum albumin modified with octanoic acid and other fatty acids. 1998 Neurochem. Res. pmid:9804287