octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Snake Bites D012909 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chickenpox D002644 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Prion Diseases D017096 2 associated lipids
Essential Tremor D020329 2 associated lipids
Gastroparesis D018589 2 associated lipids
Malocclusion D008310 3 associated lipids
Giardiasis D005873 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Gallstones D042882 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
Asthenia D001247 5 associated lipids
Liver Failure D017093 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Hypertension, Portal D006975 12 associated lipids
Crohn Disease D003424 12 associated lipids
Campylobacter Infections D002169 13 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Reye Syndrome D012202 14 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Hemorrhage D006470 15 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Endotoxemia D019446 27 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Memory Disorders D008569 33 associated lipids
Epilepsy D004827 35 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Starvation D013217 47 associated lipids
Parkinson Disease D010300 53 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Insulin Resistance D007333 99 associated lipids
Glioma D005910 112 associated lipids
Inflammation D007249 119 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Gumus S et al. The role of oxidative stress and effect of alpha-lipoic acid in reexpansion pulmonary edema - an experimental study. 2010 Arch Med Sci pmid:22427756
Lian B et al. Identification and characterization of duck plague virus glycoprotein C gene and gene product. 2010 Virol. J. pmid:21110887
Fang X et al. Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. 2010 BMC Syst Biol pmid:21092312
Little TJ and Feinle-Bisset C Oral and gastrointestinal sensing of dietary fat and appetite regulation in humans: modification by diet and obesity. 2010 Front Neurosci pmid:21088697
JunGang L et al. Cloning and biochemical characterization of a novel lipolytic gene from activated sludge metagenome, and its gene product. 2010 Microb. Cell Fact. pmid:21054894
Ruppender NS et al. Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells. 2010 PLoS ONE pmid:21085597
Xu W et al. Odorant-binding proteins of the malaria mosquito Anopheles funestus sensu stricto. 2010 PLoS ONE pmid:21042539
Casewell NR et al. Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom. 2010 PLoS Negl Trop Dis pmid:21049058
Bao F et al. New cobalt-mediated radical polymerization (CMRP) of methyl methacrylate initiated by two single-component dinuclear β-diketone cobalt (II) catalysts. 2010 PLoS ONE pmid:21049027
Kundu S and Roy D Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. 2010 Bioinformation pmid:20978606
Guo J et al. Characterization of a novel esterase Rv0045c from Mycobacterium tuberculosis. 2010 PLoS ONE pmid:20957207
Zea L et al. Chromatography-olfactometry study of the aroma of fino sherry wines. 2010 Int J Anal Chem pmid:20689702
German JB and Dillard CJ Saturated fats: a perspective from lactation and milk composition. 2010 Lipids pmid:20652757
Pulkkinen L et al. Ghrelin in diabetes and metabolic syndrome. 2010 Int J Pept pmid:20700400
Schwandt SE et al. Differential roles for octanoylated and decanoylated ghrelins in regulating appetite and metabolism. 2010 Int J Pept pmid:20700399
Wang Y et al. 5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice. 2010 BMC Cancer pmid:20678220
White AP et al. A global metabolic shift is linked to Salmonella multicellular development. 2010 PLoS ONE pmid:20676398
Abubakar IS et al. Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria. 2010 PLoS Negl Trop Dis pmid:20668549
Legrand P and Rioux V The complex and important cellular and metabolic functions of saturated fatty acids. 2010 Lipids pmid:20625935
Grossauer J et al. The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine. 2010 Bioorg. Med. Chem. pmid:20621491
Ma Y et al. Nanoparticles of Poly(Lactide-Co-Glycolide)-d-a-Tocopheryl Polyethylene Glycol 1000 Succinate Random Copolymer for Cancer Treatment. 2010 Nanoscale Res Lett pmid:20596457
Buglino JA and Resh MD Identification of conserved regions and residues within Hedgehog acyltransferase critical for palmitoylation of Sonic Hedgehog. 2010 PLoS ONE pmid:20585641
O'Bryan G et al. Stress sensing in polycaprolactone films via an embedded photochromic compound. 2010 ACS Appl Mater Interfaces pmid:20568704
Satou M et al. Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium. 2010 Endocrinology pmid:20685872
Falamarzian A and Lavasanifar A Optimization of the hydrophobic domain in poly(ethylene oxide)-poly(varepsilon-caprolactone) based nano-carriers for the solubilization and delivery of Amphotericin B. 2010 Colloids Surf B Biointerfaces pmid:20674292
Shahmoradi B et al. Modification of neodymium-doped ZnO hybrid nanoparticles under mild hydrothermal conditions. 2010 Nanoscale pmid:20648343
Karakatsani M et al. The effect of permeation enhancers on the viscosity and the release profile of transdermal hydroxypropyl methylcellulose gel formulations containing diltiazem HCl. 2010 Drug Dev Ind Pharm pmid:20545504
Sobczak M Synthesis and characterization of polyester conjugates of ciprofloxacin. 2010 Eur J Med Chem pmid:20541292
Hartmann R et al. Simultaneous biosynthesis of two copolymers in Pseudomonas putida GPo1 using a two-stage continuous culture system. 2010 Biomacromolecules pmid:20459087
Clegg ME and Shafat A Procedures in the 13C octanoic acid breath test for measurement of gastric emptying: analysis using Bland-Altman methods. 2010 Scand. J. Gastroenterol. pmid:20443742
Desjardins CA et al. The genetic basis of interspecies host preference differences in the model parasitoid Nasonia. 2010 Heredity (Edinb) pmid:20087393
Kobayashi M et al. Retarding activity of 6-O-acyl-D-alloses against plant growth. 2010 Biosci. Biotechnol. Biochem. pmid:20057117
Comar JF et al. Hepatic zonation of carbon and nitrogen fluxes derived from glutamine and ammonia transformations. 2010 J. Biomed. Sci. pmid:20055990
Nikolic L et al. Novel microwave-assisted synthesis of poly(D,L-lactide): the influence of monomer/initiator molar ratio on the product properties. 2010 Sensors (Basel) pmid:22399924
Antúnez J et al. Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities. 2010 J Venom Res pmid:21544177
Messens W et al. Inhibition of Salmonella typhimurium by medium-chain fatty acids in an in vitro simulation of the porcine cecum. 2010 Vet. Microbiol. pmid:19709819
Zhu L et al. Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. 2010 Anal Bioanal Chem pmid:20644917
Guo YJ et al. Inhibitory effects of fatty acids on the activity of mushroom tyrosinase. 2010 Appl. Biochem. Biotechnol. pmid:20544305
Coll C et al. Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports. 2010 Chemistry pmid:20645326
Okumu FO et al. Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. 2010 PLoS ONE pmid:20126628
Olanga EA et al. Attraction of Anopheles gambiae to odour baits augmented with heat and moisture. 2010 Malar. J. pmid:20051143
Azulay DO et al. Stochastic simulations of the exponential-beta function as an assessment of the validity of the choice of the Wagner-Nelson method for the analysis of ¹³C-octanoic acid breath tests. 2010 J Breath Res pmid:21383478
Chang SS et al. Inactivation of Escherichia coli O157:H7 and Salmonella spp. on alfalfa seeds by caprylic acid and monocaprylin. 2010 Int. J. Food Microbiol. pmid:20926150
Murzyn A et al. Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. 2010 PLoS ONE pmid:20706577
Patel SK et al. Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. 2010 Biomaterials pmid:19796808
Qualls-Creekmore E et al. Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury. 2010 Neurogastroenterol. Motil. pmid:19566592
Mills JK et al. The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. 2010 J. Dairy Sci. pmid:20723699
Ma J et al. Effects of cefaclor on gastric emptying and cholecystokinin release in healthy humans. 2010 Regul. Pept. pmid:19914303
Athavale M et al. Validation of a simple, rapid and cost effective method for the estimation of caprylic acid and sodium caprylate from biological products using NEFA-C kit. 2010 Biologicals pmid:19919899
Grodzki AC and Berenstein E Antibody purification: ammonium sulfate fractionation or gel filtration. 2010 Methods Mol. Biol. pmid:20012814
Ishima Y et al. One-step preparation of S-nitrosated human serum albumin with high biological activities. 2010 Nitric Oxide pmid:20451647
Grattagliano I et al. 13C-breath tests for clinical investigation of liver mitochondrial function. 2010 Eur. J. Clin. Invest. pmid:20597965
Oztürk T et al. Production of medium-chain triacylglycerols from corn oil: optimization by response surface methodology. 2010 Bioresour. Technol. pmid:20576567
Liu Y and Nair MG An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. 2010 J. Nat. Prod. pmid:20565070
Bayer S et al. Indication for a new lipolytic enzyme family: isolation and characterization of two esterases from a metagenomic library. 2010 J. Mol. Microbiol. Biotechnol. pmid:20530969
Sallam HS et al. Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20427716
Alloatti A et al. Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. 2010 PLoS ONE pmid:21151902
Mawatari H et al. The continuous real-time 13C-octanoate breath test for patients with nonalcoholic steatohepatitis using the BreathID system. 2009 Sep-Oct Hepatogastroenterology pmid:19950806
Sfarti C et al. [Prevalence of delayed gastric emptying of solids in functional dyspepsia and its relationship to symptoms]. 2009 Oct-Dec Rev Med Chir Soc Med Nat Iasi pmid:20191871
Derbocio AM et al. The action of zymosan on octanoate transport and metabolism in the isolated perfused rat liver. 2009 May-Jun J. Biochem. Mol. Toxicol. pmid:19526564
Ren Q et al. Overexpression and characterization of medium-chain-length polyhydroxyalkanoate granule bound polymerases from Pseudomonas putida GPo1. 2009 Microb. Cell Fact. pmid:19925642
Mizutani M et al. Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501445
Masaoka T and Tack J Gastroparesis: current concepts and management. 2009 Gut Liver pmid:20431741
Mahmud A et al. Self-associating poly(ethylene oxide)-b-poly(alpha-cholesteryl carboxylate-epsilon-caprolactone) block copolymer for the solubilization of STAT-3 inhibitor cucurbitacin I. 2009 Biomacromolecules pmid:19175305
Mendonça Ade L et al. Antimicrobial activities of components of the glandular secretions of leaf cutting ants of the genus Atta. 2009 Antonie Van Leeuwenhoek pmid:19214771
Formisano C et al. Headspace volatile composition of the flowers of Caralluma europaea N.E.Br. (Apocynaceae). 2009 Molecules pmid:19924088
Müller T Levodopa/carbidopa and entacapone in the treatment of Parkinson's disease: efficacy, safety and patient preference. 2009 Patient Prefer Adherence pmid:19936145
Wang DB et al. Detection of B. anthracis spores and vegetative cells with the same monoclonal antibodies. 2009 PLoS ONE pmid:19915677
Stanley FE et al. Rapid determination of surfactant critical micelle concentrations using pressure-driven flow with capillary electrophoresis instrumentation. 2009 J Chromatogr A pmid:19836753
Jung SY et al. Formulation and evaluation of ubidecarenone transdermal delivery systems. 2009 Drug Dev Ind Pharm pmid:19365779
Clifton JG et al. Proteomic characterization of plasma-derived clotting factor VIII-von Willebrand factor concentrates. 2009 Electrophoresis pmid:19768705
Wang Q et al. Complete PHB mobilization in Escherichia coli enhances the stress tolerance: a potential biotechnological application. 2009 Microb. Cell Fact. pmid:19719845
Gunschera J et al. Surface-catalysed reactions on pollutant-removing building products for indoor use. 2009 Chemosphere pmid:19181362
Liu JH et al. The fabrication of polycrystalline silver nanowires via self-assembled nanotubes at controlled temperature. 2009 Nanotechnology pmid:19417290
Pan J et al. Alternative block polyurethanes based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(ethylene glycol). 2009 Biomaterials pmid:19230967
Miura T et al. Purification and properties of ghrelin from the intestine of the goldfish, Carassius auratus. 2009 Peptides pmid:19150635
Wang YC et al. Thermoresponsive block copolymers of poly(ethylene glycol) and polyphosphoester: thermo-induced self-assembly, biocompatibility, and hydrolytic degradation. 2009 Biomacromolecules pmid:19133835
Jo YH et al. Oleic acid directly regulates POMC neuron excitability in the hypothalamus. 2009 J. Neurophysiol. pmid:19261705
Tham E et al. Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19240252
Eagle RA et al. Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G. 2009 PLoS ONE pmid:19223974
Sobczak M and Kolodziejski W Polymerization of cyclic esters initiated by carnitine and tin (II) octoate. 2009 Molecules pmid:19214152
Gong CY et al. In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) copolymer. 2009 BMC Biotechnol. pmid:19210779
Kemmer D et al. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. 2009 BMC Microbiol. pmid:19144191
Takahashi K et al. Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolism. 2009 PLoS ONE pmid:19119319
Stephenson D and Halpern BP No oral-cavity-only discrimination of purely olfactory odorants. 2009 Chem. Senses pmid:18948567
Yang JY et al. Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail. 2009 J. Nutr. Biochem. pmid:18789670
Wu R et al. Spatially directional multiarm poly(epsilon-caprolactone) based on resorcin[4]arene cavitand core. 2009 Chem. Commun. (Camb.) pmid:19319413
Jennings BH and Akoh CC Characterization of a rice bran oil structured lipid. 2009 J. Agric. Food Chem. pmid:19284800
Hamel FG Preliminary report: inhibition of cellular proteasome activity by free fatty acids. 2009 Metab. Clin. Exp. pmid:19423142
Keller J et al. Influence of clinical parameters on the results of 13C-octanoic acid breath tests: examination of different mathematical models in a large patient cohort. 2009 Neurogastroenterol. Motil. pmid:19549136
Sugiyama E et al. Desirable pharmacokinetic properties of (13)C-uracil as a breath test probe of gastric emptying in comparison with (13)C-acetate and (13)C-octanoate in rats. 2009 Scand. J. Gastroenterol. pmid:19585373
Chen YM and Guo LH Combined fluorescence and electrochemical investigation on the binding interaction between organic acid and human serum albumin. 2009 J Environ Sci (China) pmid:19634451
Dzikovski B et al. Multifrequency ESR study of spin-labeled molecules in inclusion compounds with cyclodextrins. 2009 Phys Chem Chem Phys pmid:19639141
Segura A et al. Stability of equine IgG antivenoms obtained by caprylic acid precipitation: towards a liquid formulation stable at tropical room temperature. 2009 Toxicon pmid:19673074
Yamamoto K et al. An LC method for monitoring medium-chain fatty acid permeation through CaCo-2 cell monolayers. 2009 Anal Bioanal Chem pmid:19641905
Barrena HC et al. Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia. 2009 Cell Biochem. Funct. pmid:19623545
Takahashi T et al. Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, as well as n-octanoic acid. 2009 J. Biochem. pmid:19628676
Terai S et al. Lack of modulation of gastric emptying by dietary nitrate in healthy volunteers. 2009 Tohoku J. Exp. Med. pmid:19398876
Gurvitz A The essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2. 2009 Mol. Genet. Genomics pmid:19685079
Page KA et al. Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia. 2009 Diabetes pmid:19223595