octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sarel I and Widmaier EP | Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. | 1995 | Am. J. Physiol. | pmid:7611525 |
McDaniel HG | Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. | 1975 | Am. J. Physiol. | pmid:1211489 |
Matsumura T et al. | O2 uptake in periportal and pericentral regions of liver lobule in perfused liver. | 1986 | Am. J. Physiol. | pmid:3717341 |
ChacÃn J et al. | Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. | 1986 | Am. J. Physiol. | pmid:3090895 |
Coyle EF et al. | Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. | 1997 | Am. J. Physiol. | pmid:9277379 |
Ben Cheikh R et al. | Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates. | 1994 | Am. J. Physiol. | pmid:8203607 |
Hütter JF et al. | Effect of fatty acid oxidation on efficiency of energy production in rat heart. | 1985 | Am. J. Physiol. | pmid:4051011 |
Witters LA and Trasko CS | Regulation of hepatic free fatty acid metabolism by glucagon and insulin. | 1979 | Am. J. Physiol. | pmid:157075 |
ChacÃn J et al. | Role of fatty acid oxidation in mechanism of action of gastric secretagogues. | 1980 | Am. J. Physiol. | pmid:6768310 |
Bielefeld DR et al. | Altered sensitivity of chronic diabetic rat heart to calcium. | 1983 | Am. J. Physiol. | pmid:6362427 |