octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zammit VA | The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. | 1980 | Biochem. J. | pmid:7470052 |
Petcu LG and Plaut GW | NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. | 1980 | Biochem. J. | pmid:7470071 |
Trauner DA | Regional cerebral Na+K+ ATPase activity following octanoate administration. | 1980 | Pediatr. Res. | pmid:6250122 |
Barth CA et al. | Morphology and metabolism of adult rat hepatocytes in primary culture. | 1980 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6997170 |
Caffier G et al. | The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. | 1980 | Pflugers Arch. | pmid:6966791 |
Kössler F et al. | Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. | 1980 | Chem. Biol. Interact. | pmid:6967777 |
Caffier G and Küchler G | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. | 1980 | Acta Biol. Med. Ger. | pmid:6969509 |
Burns AH and Reddy WJ | Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. | 1981 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:6267674 |
Carrington MJ et al. | Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. | 1981 | Biochem. Soc. Trans. | pmid:7215663 |
Wells JW et al. | The biosynthesis of progesterone by fowl granulosa cells in vitro from 14C-labelled substrates. | 1981 | J. Steroid Biochem. | pmid:7265968 |
Trauner DA and Adams H | Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. | 1981 | Pediatr. Res. | pmid:7267183 |
Ferré P et al. | Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. | 1981 | Biochem. J. | pmid:7340842 |