octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Starvation D013217 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Epilepsy D004827 35 associated lipids
Memory Disorders D008569 33 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Obesity D009765 29 associated lipids
Endotoxemia D019446 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Poultry Diseases D011201 21 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Hemorrhage D006470 15 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Reye Syndrome D012202 14 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Chronic Disease D002908 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Gallstones D042882 3 associated lipids
Malocclusion D008310 3 associated lipids
Giardiasis D005873 3 associated lipids
Gastroparesis D018589 2 associated lipids
Prion Diseases D017096 2 associated lipids
Essential Tremor D020329 2 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chickenpox D002644 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Samant MP et al. Novel analogues of degarelix incorporating hydroxy-, methoxy-, and pegylated-urea moieties at positions 3, 5, 6 and the N-terminus. Part III. 2006 J. Med. Chem. pmid:16759096
Delamarre SC and Batt CA Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha. 2006 Appl. Microbiol. Biotechnol. pmid:16362422
Amalaradjou MA et al. Inactivation of escherichia coli O157:H7 in cattle drinking water by sodium caprylate. 2006 J. Food Prot. pmid:16995532
Darnell ME and Taylor DR Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products. 2006 Transfusion pmid:17002634
Jones PM et al. Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts. 2006 Biochem. Biophys. Res. Commun. pmid:16750167
Bouvet L et al. Erythromycin promotes gastric emptying during acute pain in volunteers. 2006 Anesth. Analg. pmid:16717329
Otero R et al. Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia. 2006 Trans. R. Soc. Trop. Med. Hyg. pmid:16698053
Vanden Heuvel JP et al. Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. 2006 Toxicol. Sci. pmid:16731579
Wilson TA et al. Structured triglycerides containing caprylic (8:0) and oleic (18:1) fatty acids reduce blood cholesterol concentrations and aortic cholesterol accumulation in hamsters. 2006 Biochim. Biophys. Acta pmid:16580874
Kachi M et al. Effects of Helicobacter pylori eradication therapy on gastric emptying measured using the 13C-octanoic acid breath test and the acetaminophen method. 2006 J. Gastroenterol. Hepatol. pmid:16704530
Tao F et al. Competition and coadsorption of di-acids and carboxylic acid solvents on HOPG. 2006 J Phys Chem B pmid:17004820
Hellmig S et al. Gastric emptying time of fluids and solids in healthy subjects determined by 13C breath tests: influence of age, sex and body mass index. 2006 J. Gastroenterol. Hepatol. pmid:17074022
Kragh-Hansen U et al. Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis. 2006 J. Mol. Biol. pmid:16979183
Thorburn MS et al. Attenuated gastric distress but no benefit to performance with adaptation to octanoate-rich esterified oils in well-trained male cyclists. 2006 J. Appl. Physiol. pmid:16840580
Brill J et al. Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami. 2006 J. Neurosci. pmid:16793888
Gerhardt WW et al. Functional lactide monomers: methodology and polymerization. 2006 Biomacromolecules pmid:16768392
Aydin HM et al. Attachment and growth of fibroblasts on poly(L-lactide/epsilon-caprolactone) scaffolds prepared in supercritical CO2 and modified by polyethylene imine grafting with ethylene diamine-plasma in a glow-discharge apparatus. 2006 Int J Artif Organs pmid:17033995
Gasbarrini G et al. Evaluation of thermal water in patients with functional dyspepsia and irritable bowel syndrome accompanying constipation. 2006 World J. Gastroenterol. pmid:16688801
Hosoda H et al. Biological, physiological, and pharmacological aspects of ghrelin. 2006 J. Pharmacol. Sci. pmid:16612045
Puigmartí-Luis J et al. Noncovalent control for bottom-up assembly of functional supramolecular wires. 2006 J. Am. Chem. Soc. pmid:17002326
Perri F et al. 13C-octanoic acid breath test for measuring gastric emptying of solids. 2005 Sep-Oct Eur Rev Med Pharmacol Sci pmid:16457123
Usai Satta P et al. 13C-octanoic acid breath test in functional and organic disease: critical review of literature. 2005 Sep-Oct Eur Rev Med Pharmacol Sci pmid:16457124
Bonazzi P et al. Gastric emptying and intragastric balloon in obese patients. 2005 Sep-Oct Eur Rev Med Pharmacol Sci pmid:16457125
Rossi Z et al. Electrogastrography. 2005 Sep-Oct Eur Rev Med Pharmacol Sci pmid:16457127
Borba-Murad GR et al. Comparative acute effects of leptin and insulin on gluconeogenesis and ketogenesis in perfused rat liver. 2005 Nov-Dec Cell Biochem. Funct. pmid:15543644
Sharma P et al. Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers. 2005 Nov-Dec Farmaco pmid:16226752
Vikbjerg AF et al. Lipase-catalyzed acyl exchange of soybean phosphatidylcholine in n-Hexane: a critical evaluation of both acyl incorporation and product recovery. 2005 Mar-Apr Biotechnol. Prog. pmid:15801777
Mahadevia PJ et al. Cost savings from intravenous immunoglobulin manufactured from chromotography/caprylate (IGIV-C) in persons with primary humoral immunodeficiency disorder. 2005 Jul-Aug Value Health pmid:16091026
Kandare E and Hossenlopp JM Hydroxy double salt anion exchange kinetics: effects of precursor structure and anion size. 2005 J Phys Chem B pmid:16851994
León G et al. Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols. 2005 Toxicon pmid:15581691
Tachibana S et al. Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes. 2005 Biochim. Biophys. Acta pmid:16226916
Jordanova R et al. The highly abundant protein Ag-lbp55 from Ascaridia galli represents a novel type of lipid-binding proteins. 2005 J. Biol. Chem. pmid:16210327
Schneider AR et al. Total body metabolism of 13C-octanoic acid is preserved in patients with non-alcoholic steatohepatitis, but differs between women and men. 2005 Eur J Gastroenterol Hepatol pmid:16215429
Bian F et al. Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. 2005 J. Biol. Chem. pmid:15611129
Skrivanová E et al. Susceptibility of Clostridium perfringens to C-C fatty acids. 2005 Lett. Appl. Microbiol. pmid:15960756
Lee MY et al. Synthesis of chitosan-based polymeric surfactants and their adsorption properties for heavy metals and fatty acids. 2005 Int. J. Biol. Macromol. pmid:16011843
Nair MK et al. Antibacterial effect of caprylic acid and monocaprylin on major bacterial mastitis pathogens. 2005 J. Dairy Sci. pmid:16162522
Gambert S et al. Regulation of intermediary metabolism in rat cardiac myocyte by extracellular glycerol. 2005 Biochim. Biophys. Acta pmid:16153888
Herrera M et al. Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs. 2005 Toxicon pmid:16183094
Kim BH and Akoh CC Modeling of lipase-catalyzed acidolysis of sesame oil and caprylic Acid by response surface methodology: optimization of reaction conditions by considering both acyl incorporation and migration. 2005 J. Agric. Food Chem. pmid:16190667
Seyfried TN and Mukherjee P Targeting energy metabolism in brain cancer: review and hypothesis. 2005 Nutr Metab (Lond) pmid:16242042
Labarthe F et al. Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15550523
Hung HM et al. Products and mechanisms of the reaction of oleic acid with ozone and nitrate radical. 2005 J Phys Chem A pmid:16833788
Mahadevia PJ The pocketbook: Pharmacoeconomic issues related to intravenous immunoglobulin therapy. 2005 Pharmacotherapy pmid:16229680
Omari TI et al. Is the correction factor used in the breath test assessment of gastric emptying appropriate for use in infants? 2005 J. Pediatr. Gastroenterol. Nutr. pmid:16131989
Shah S Pharmacy considerations for the use of IGIV therapy. 2005 Am J Health Syst Pharm pmid:16100386
Thennarasu S et al. Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843. 2005 Biochim. Biophys. Acta pmid:15904663
Hong J et al. The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. 2005 Metab. Clin. Exp. pmid:16154432
Kalantar-Zadeh K et al. An anti-inflammatory and antioxidant nutritional supplement for hypoalbuminemic hemodialysis patients: a pilot/feasibility study. 2005 J Ren Nutr pmid:16007562
Tissier C et al. Substrate dependence of the postischemic cardiomyocyte recovery: dissociation between functional, metabolic and injury markers. 2005 Mol. Cell. Biochem. pmid:16013439