octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Oiso S et al. | Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. | 2015 | J Oleo Sci | pmid:26521811 |
Rosiak J and Olejniczak J | [Polymer materials for biomedical use obtained by radiation methods. IV. The therapeutic system for local release of prostaglandins]. | 1989 | Polim Med | pmid:2641404 |
Parshintsev J et al. | Desorption atmospheric pressure photoionization high-resolution mass spectrometry: a complementary approach for the chemical analysis of atmospheric aerosols. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26395607 |
Fredrickson J et al. | The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model. | 2015 | J. Assist. Reprod. Genet. | pmid:26342329 |
pmid:26280674 | ||||
Wang L et al. | Octanoylated ghrelin attenuates angiogenesis induced by oxLDL in human coronary artery endothelial cells via the GHSR1a-mediated NF-κB pathway. | 2015 | Metab. Clin. Exp. | pmid:26277200 |
Kim SA and Rhee MS | Use of caprylic acid to control pathogens (Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium) in apple juice at mild heat temperature. | 2015 | J. Appl. Microbiol. | pmid:26257401 |
pmid:26253695 | ||||
Kajimoto M et al. | Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26232235 |
Librán-Pérez M et al. | Effects of insulin treatment on the response to oleate and octanoate of food intake and fatty acid-sensing systems in rainbow trout. | 2015 | Domest. Anim. Endocrinol. | pmid:26226227 |
Lemarié F et al. | Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. | 2015 | PLoS ONE | pmid:26196391 |
Genser B et al. | Within- and between-group regression for improving the robustness of causal claims in cross-sectional analysis. | 2015 | Environ Health | pmid:26159541 |
Upadhyaya I et al. | Reducing Colonization and Eggborne Transmission of Salmonella Enteritidis in Layer Chickens by In-Feed Supplementation of Caprylic Acid. | 2015 | Foodborne Pathog. Dis. | pmid:26135893 |
pmid:26129951 | ||||
Mohanty JG and Elazhary Y | Purification of IgG from serum with caprylic acid and ammonium sulphate precipitation is not superior to ammonium sulphate precipitation alone. | 1989 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:2612135 |
Hovorková P and Skřivanová E | Use of Caprylic Acid in Broiler Chickens: Effect on Campylobacter jejuni. | 2015 | Foodborne Pathog. Dis. | pmid:26114373 |
Kadota Y et al. | Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. | 2015 | Metab. Clin. Exp. | pmid:26104959 |
Epprecht L et al. | Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal. | 2015 | J. Neurol. | pmid:26048686 |
Nishitani N et al. | Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. | 2015 | Chem Asian J | pmid:26033832 |
Coronado MA et al. | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. | 2015 | Curr. Protein Pept. Sci. | pmid:25961401 |
Arora T et al. | Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission. | 2015 | PLoS ONE | pmid:25946120 |
Pesce P et al. | Gastric and masticatory performances in full-arch immediate loading rehabilitated patients. | 2015 | J Oral Rehabil | pmid:25882620 |
Kim SA and Rhee MS | Synergistic antimicrobial activity of caprylic acid in combination with citric acid against both Escherichia coli O157:H7 and indigenous microflora in carrot juice. | 2015 | Food Microbiol. | pmid:25846927 |
RodrÃguez-Moyá M and Gonzalez R | Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. | 2015 | J Proteomics | pmid:25845584 |
Chen Y et al. | Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. | 2015 | Int J Pharm | pmid:25841571 |
Damitz R and Chauhan A | Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. | 2015 | Int J Pharm | pmid:25839419 |
Royce LA et al. | Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity. | 2015 | Metab. Eng. | pmid:25839166 |
Xu J et al. | In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. | 2015 | Chem. Commun. (Camb.) | pmid:25792085 |
Borrull A et al. | New insights into the toxicity mechanism of octanoic and decanoic acids on Saccharomyces cerevisiae. | 2015 | Yeast | pmid:25773463 |
Narayanan A et al. | Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cancer cells in vitro. | 2015 | Int J Mol Sci | pmid:25749477 |
Sengupta A et al. | Production of medium chain fatty acid rich mustard oil using packed bed bioreactor. | 2015 | J Oleo Sci | pmid:25748375 |
El-Ekiaby M et al. | Minipool caprylic acid fractionation of plasma using disposable equipment: a practical method to enhance immunoglobulin supply in developing countries. | 2015 | PLoS Negl Trop Dis | pmid:25719558 |
Alonso C et al. | Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol. | 2015 | J. Pharm. Pharmacol. | pmid:25645286 |
Vidal H et al. | Vasoactive intestinal peptide stimulates long-chain fatty acid oxidation and inhibits acetyl-coenzyme A carboxylase activity in isolated rat enterocytes. | 1989 | J. Biol. Chem. | pmid:2564395 |
Obeso JI et al. | The loss of function of PhaC1 is a survival mechanism that counteracts the stress caused by the overproduction of poly-3-hydroxyalkanoates in Pseudomonas putidaΔfadBA. | 2015 | Environ. Microbiol. | pmid:25627209 |
Fu Y et al. | Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25620365 |
Jha SK and Hayashi K | A quick responding quartz crystal microbalance sensor array based on molecular imprinted polyacrylic acids coating for selective identification of aldehydes in body odor. | 2015 | Talanta | pmid:25618646 |
Xu J et al. | Dual receptor-targeting â¹â¹mTc-labeled Arg-Gly-Asp-conjugated Alpha-Melanocyte stimulating hormone hybrid peptides for human melanoma imaging. | 2015 | Nucl. Med. Biol. | pmid:25577037 |
Kim SA and Rhee MS | Predictive model and optimization of a combined treatment of caprylic acid and citric acid for the reduction of Escherichia coli O157:H7 using the response surface methodology. | 2015 | Int. J. Food Microbiol. | pmid:25544642 |
Rosenblatt J et al. | Caprylic acid and glyceryl trinitrate combination for eradication of biofilm. | 2015 | Antimicrob. Agents Chemother. | pmid:25534725 |
Azain MJ and Ontko JA | An explanation for decreased ketogenesis in the liver of the obese Zucker rat. | 1989 | Am. J. Physiol. | pmid:2552844 |
Gourcerol G et al. | Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. | 2015 | Aliment. Pharmacol. Ther. | pmid:25523288 |
Vargas M et al. | Human plasma-derived immunoglobulin G fractionated by an aqueous two-phase system, caprylic acid precipitation, and membrane chromatography has a high purity level and is free of detectable in vitro thrombogenic activity. | 2015 | Vox Sang. | pmid:25469648 |
Socała K et al. | Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice. | 2015 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:25455587 |
Wlaź P et al. | Acute anticonvulsant effects of capric acid in seizure tests in mice. | 2015 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:25445478 |
Skřivanová E et al. | Potential use of caprylic acid in broiler chickens: effect on Salmonella enteritidis. | 2015 | Foodborne Pathog. Dis. | pmid:25407657 |
Goodwin D et al. | Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides. | 2015 | Pharm. Res. | pmid:25407542 |
Olivieri MC and Botelho LH | Synergistic inhibition of hepatic ketogenesis in the presence of insulin and a cAMP antagonist. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2539126 |
Marchington DR et al. | Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat hepatocytes. | 1989 | Biochem. J. | pmid:2539088 |
Olson JE et al. | Octanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome. | 1989 | J. Neurochem. | pmid:2538563 |
Sengupta A et al. | Antioxidative effect of rice bran oil and medium chain fatty acid rich rice bran oil in arsenite induced oxidative stress in rats. | 2014 | J Oleo Sci | pmid:25354877 |
Nass R et al. | The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. | 2015 | J. Clin. Endocrinol. Metab. | pmid:25337923 |
Chang P et al. | Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. | 2015 | J. Pharmacol. Exp. Ther. | pmid:25326131 |
Cherniavs'kyÄ VV | [Clinical use of 13C-breath tests in esophagogastroduodenal diseases]. | 2014 Mar-Apr | Lik. Sprava | pmid:25286602 |
Caballero E et al. | Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases. | 2014 | PLoS ONE | pmid:25248107 |
Schubert MM et al. | Coffee for morning hunger pangs. An examination of coffee and caffeine on appetite, gastric emptying, and energy intake. | 2014 | Appetite | pmid:25218717 |
Coenen MJ et al. | Nanostructuring of self-assembled porphyrin networks at a solid/liquid interface: local manipulation under global control. | 2014 | Chemphyschem | pmid:25146424 |
Razmakhnin EV et al. | [The atomic emission analysis under examination of composition of gallstones]. | 2014 | Klin. Lab. Diagn. | pmid:25080794 |
el Alaoui-Talibi Z and Moravec J | Limitation of long chain fatty acid oxidation in volume over-loaded rat hearts. | 1989 | Adv. Exp. Med. Biol. | pmid:2506741 |
Wolfram G et al. | [Distribution and elimination of medium- and long-chain fatty acids of a fat emulsion in lipoproteins of severely injured patients following bolus injection]. | 1989 | Z Ernahrungswiss | pmid:2503947 |
Zieve L and Lyftogt C | Valproic acid induction of coma in rats: synergism with NH4+ and pentobarbital. | 1989 | Metab Brain Dis | pmid:2502706 |
Jensen GL et al. | Dietary modification of chyle composition in chylothorax. | 1989 | Gastroenterology | pmid:2502466 |
Zhu J et al. | The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates. | 2014 | Nutrients | pmid:25010553 |
el Alaoui-Talibi Z and Moravec J | Carnitine transport and exogenous palmitate oxidation in chronically volume-overloaded rat hearts. | 1989 | Biochim. Biophys. Acta | pmid:2499353 |
Bagai S et al. | Lipid-modified polyethylenimine-mediated DNA attraction evaluated by molecular dynamics simulations. | 2014 | J Phys Chem B | pmid:24918771 |
Gasco MR et al. | Microemulsions as topical delivery vehicles: ocular administration of timolol. | 1989 | J Pharm Biomed Anal | pmid:2490750 |
Salentinig S et al. | pH-responsive micelles based on caprylic acid. | 2014 | Langmuir | pmid:24905895 |
Matsumoto Y et al. | Rectal absorption enhancement of gentamicin in rabbits from hollow type suppositories by sodium salicylate or sodium caprylate. | 1989 | Drug Des. Deliv. | pmid:2490276 |
Mitkov D | Octanoate action on muscular protein catabolism in rats. | 1989 | Folia Med (Plovdiv) | pmid:2490157 |
Dalgaard L et al. | Resolution and binding site determination of D,L-thyronine by high-performance liquid chromatography using immobilized albumin as chiral stationary phase. Determination of the optical purity of thyroxine in tablets. | 1989 | J Pharm Biomed Anal | pmid:2488636 |
Morimoto K et al. | Effect of medium-chain fatty acid salts on penetration of a hydrophilic compound and a macromolecular compound across rabbit corneas. | 1989 Nov-Dec | Arch Int Pharmacodyn Ther | pmid:2484010 |
Sun X et al. | Tuning the self-assembly of oligothiophenes on chemical vapor deposition graphene: effect of functional group, solvent, and substrate. | 2014 | Chem Asian J | pmid:24839081 |
Lavieri NA et al. | Investigating the control of Listeria monocytogenes on a ready-to-eat ham product using natural antimicrobial ingredients and postlethality interventions. | 2014 | Foodborne Pathog. Dis. | pmid:24824223 |
De Preter V et al. | Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. | 2015 | Gut | pmid:24811995 |
Lavieri NA et al. | Investigating the control of Listeria monocytogenes on alternatively-cured frankfurters using natural antimicrobial ingredients or post-lethality interventions. | 2014 | Meat Sci. | pmid:24769878 |
Darling RA et al. | Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24760994 |
Adamczak M | Characteristic of fungal lipases and their application in synthesis of structered lipids. | 2003 | Commun. Agric. Appl. Biol. Sci. | pmid:24757817 |
Layek B and Singh J | N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. | 2012 | Carbohydr Polym | pmid:24750737 |
Tao Y et al. | Enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. | 2014 | Enzyme Microb. Technol. | pmid:24731826 |
Marquez A et al. | Optimization and validation of an automated DHS-TD-GC-MS method for the determination of aromatic esters in sweet wines. | 2014 | Talanta | pmid:24725861 |
Morais V et al. | Immunoglobulin purification by caprylic acid. | 2014 | Methods Mol. Biol. | pmid:24648074 |
Librán-Pérez M et al. | Central administration of oleate or octanoate activates hypothalamic fatty acid sensing and inhibits food intake in rainbow trout. | 2014 | Physiol. Behav. | pmid:24631300 |
Chen YJ et al. | Production and characterization of medium-chain-length polyhydroxyalkanoates by Pseudomonas mosselii TO7. | 2014 | J. Biosci. Bioeng. | pmid:24630613 |
Ke L et al. | Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution. | 2014 | Crit Care Resusc | pmid:24588433 |
Kajimoto M et al. | Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24531815 |
Paulsen SJ et al. | Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. | 2014 | PLoS ONE | pmid:24520357 |
Bruno G et al. | 13C-octanoic acid breath test to study gastric emptying time. | 2013 | Eur Rev Med Pharmacol Sci | pmid:24443070 |
Gadotti C et al. | Inhibitory effect of combinations of caprylic acid and nisin on Listeria monocytogenes in queso fresco. | 2014 | Food Microbiol. | pmid:24387845 |
Qin XL et al. | Fatty acid specificity of T1 lipase and its potential in acylglycerol synthesis. | 2014 | J. Sci. Food Agric. | pmid:24338705 |
Kössler F and Nasledov GA | Effects of Na-octanoate on potassium contractures in normal and denervated frog tonic fibres. | 1986 | Gen. Physiol. Biophys. | pmid:2433184 |
Shilling M et al. | Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. | 2013 | J Med Food | pmid:24328700 |
Antón MJ et al. | Aromatic profile of ciders by chemical quantitative, gas chromatography-olfactometry, and sensory analysis. | 2014 | J. Food Sci. | pmid:24313985 |
Bokhout BA et al. | Porcine IgG. Isolation of two IgG-subclasses and anti-IgG class- and subclass-specific antibodies. | 1986 | Mol. Immunol. | pmid:2427943 |
Lee YC and Johnson JH | Determination of sodium caprylate in plasma volume expanders by gas chromatography. | 1986 | J. Chromatogr. | pmid:2426293 |
Al-Abdulla I et al. | Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid. | 2014 | J. Immunol. Methods | pmid:24246428 |
Zhang JF et al. | A new derivatization method to enhance sensitivity for the determination of low levels of valproic acid in human plasma. | J Chromatogr Sci | pmid:24243686 | |
de Oliveira AL et al. | Adrenergic metabolic and hemodynamic effects of octopamine in the liver. | 2013 | Int J Mol Sci | pmid:24196353 |
Scott G et al. | Pickering stabilized peptide gel particles as tunable microenvironments for biocatalysis. | 2013 | Langmuir | pmid:24144273 |
Kursu VA et al. | Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. | 2013 | Mol. Microbiol. | pmid:24102902 |
Horner KM et al. | Reproducibility of gastric emptying in overweight and obese males. | 2014 | Clin Nutr | pmid:24074547 |