octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Carrington MJ et al. | Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. | 1981 | Biochem. Soc. Trans. | pmid:7215663 |
Parameswaran M and Arinze IJ | Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria. | 1981 | Biochim. Biophys. Acta | pmid:7225415 |
Chace KV and Odessey R | The utilization by rabbit aorta of carbohydrates, fatty acids, ketone bodies, and amino acids as substrates for energy production. | 1981 | Circ. Res. | pmid:7226445 |
Borg LA | Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. | 1981 | Acta Endocrinol. | pmid:7010865 |
Rosario P and Medina JM | Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. | 1981 | Rev. Esp. Fisiol. | pmid:7244329 |
Sumbilla CM et al. | Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:7272339 |
Kaler LW and Neaves WB | The steroidogenic capacity of the aging rat testis. | 1981 | J Gerontol | pmid:7252069 |
Dimenna GP and Emery RS | Palmitate and octanoate metabolism in bovine mammary tissue. | 1981 | J. Dairy Sci. | pmid:7264015 |
Wells JW et al. | The biosynthesis of progesterone by fowl granulosa cells in vitro from 14C-labelled substrates. | 1981 | J. Steroid Biochem. | pmid:7265968 |
Trauner DA and Adams H | Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. | 1981 | Pediatr. Res. | pmid:7267183 |
Ferré P et al. | Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. | 1981 | Biochem. J. | pmid:7340842 |
Burns AH and Reddy WJ | Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. | 1981 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:6267674 |
Henze K et al. | The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:6118180 |
Müller MJ et al. | Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. | 1981 | Biochim. Biophys. Acta | pmid:6275888 |
Pegg DE et al. | Metabolism of normal and ischemically injured rabbit kidneys during perfusion for 48 hours at 10 C. | 1981 | Transplantation | pmid:7330963 |
Morgenthaler JJ et al. | Fatty acid patterns during plasma fractionation. | 1980 | Vox Sang. | pmid:7415075 |
Schenk J et al. | Treatment of choledocholithiasis using the transpapillary perfusion technique. | 1980 | Endoscopy | pmid:7428727 |
Krisans SK et al. | Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. | 1980 | J. Biol. Chem. | pmid:7430088 |
Waymack PP et al. | Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. | 1980 | J. Biol. Chem. | pmid:7430101 |
Barth CA et al. | Morphology and metabolism of adult rat hepatocytes in primary culture. | 1980 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6997170 |