octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Amlou M et al. | Genetic analysis of Drosophila sechellia specialization: oviposition behavior toward the major aliphatic acids of its host plant. | 1998 | Behav. Genet. | pmid:9926614 |
Wang Z and Zhang Q | [Study on pulmonary delivery system of salmon calcitonin in rats]. | 2003 | Beijing Da Xue Xue Bao | pmid:12914259 |
Böhles H et al. | The influence of i.v. MCT and carnitine on the excretion of dicarboxylic acids. | 1988 | Beitr Infusionther Klin Ernahr | pmid:3132147 |
Lee SM et al. | Prevention of the metabolic effects of 2-tetradecylglycidate by octanoic acid in the genetically diabetic mouse (db/db). | 1985 | Biochem Med | pmid:3994695 |
Lutz WH et al. | Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides. | 1985 | Biochem Med | pmid:4052056 |
Suzuki S et al. | Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23376076 |
Oettl K et al. | An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12767923 |