octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Asthenia D001247 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Fistula D001658 13 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Chest Pain D002637 4 associated lipids
Chickenpox D002644 1 associated lipids
Chronic Disease D002908 7 associated lipids
Chylothorax D002916 1 associated lipids
Coccidiosis D003048 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Crohn Disease D003424 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Diarrhea D003967 32 associated lipids
Dumping Syndrome D004377 1 associated lipids
Dyspepsia D004415 5 associated lipids
Edema D004487 152 associated lipids
Epilepsy D004827 35 associated lipids
Flatulence D005414 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Giardiasis D005873 3 associated lipids
Glioma D005910 112 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Malocclusion D008310 3 associated lipids
Memory Disorders D008569 33 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Obesity D009765 29 associated lipids
Parkinson Disease D010300 53 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Reye Syndrome D012202 14 associated lipids
Schistosomiasis D012552 4 associated lipids
Seizures D012640 87 associated lipids
Snake Bites D012909 1 associated lipids
Starvation D013217 47 associated lipids
Stomach Diseases D013272 7 associated lipids
Urinary Incontinence D014549 4 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Critical Illness D016638 13 associated lipids
Liver Failure D017093 5 associated lipids
Prion Diseases D017096 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Gastroparesis D018589 2 associated lipids
Endotoxemia D019446 27 associated lipids
Intracranial Hypertension D019586 4 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Essential Tremor D020329 2 associated lipids
Gallstones D042882 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Gunschera J et al. Surface-catalysed reactions on pollutant-removing building products for indoor use. 2009 Chemosphere pmid:19181362
Mahmud A et al. Self-associating poly(ethylene oxide)-b-poly(alpha-cholesteryl carboxylate-epsilon-caprolactone) block copolymer for the solubilization of STAT-3 inhibitor cucurbitacin I. 2009 Biomacromolecules pmid:19175305
Sun SY et al. Novel minor lipase from Rhizopus chinensis during solid-state fermentation: biochemical characterization and its esterification potential for ester synthesis. 2009 Bioresour. Technol. pmid:19157870
Miura T et al. Purification and properties of ghrelin from the intestine of the goldfish, Carassius auratus. 2009 Peptides pmid:19150635
Kemmer D et al. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. 2009 BMC Microbiol. pmid:19144191
Wang YC et al. Thermoresponsive block copolymers of poly(ethylene glycol) and polyphosphoester: thermo-induced self-assembly, biocompatibility, and hydrolytic degradation. 2009 Biomacromolecules pmid:19133835
Butterworth RF Pathophysiology of hepatic encephalopathy: The concept of synergism. 2008 Hepatol. Res. pmid:19125942
Takahashi K et al. Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolism. 2009 PLoS ONE pmid:19119319
Li G et al. Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome. 2008 Microb. Cell Fact. pmid:19116015
Pandey A and Aswath PB Microwave synthesis of poly(L-lactic acid). 2009 J Biomater Sci Polym Ed pmid:19105899
Cai L et al. Enhanced production of medium-chain-length polyhydroxyalkanoates (PHA) by PHA depolymerase knockout mutant of Pseudomonas putida KT2442. 2009 Bioresour. Technol. pmid:19103481
Solis de los Santos F et al. The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. 2009 Poult. Sci. pmid:19096058
Yang BY et al. Preparation and physical properties of chitin fatty acids esters. 2009 Carbohydr. Res. pmid:19091309
Iwahashi H High performance liquid chromatography/electron spin resonance/mass spectrometry analyses of lipid-derived radicals. 2008 Methods Mol. Biol. pmid:19082939
Padmalayam I et al. Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance. 2009 Diabetes pmid:19074983
Phillips PS et al. Myotoxic reactions to lipid-lowering therapy are associated with altered oxidation of fatty acids. 2009 Endocrine pmid:19051066
Nazzi F et al. Octanoic acid confers to royal jelly varroa-repellent properties. 2009 Naturwissenschaften pmid:19050844
Elbahloul Y and Steinbüchel A Large-scale production of poly(3-hydroxyoctanoic acid) by Pseudomonas putida GPo1 and a simplified downstream process. 2009 Appl. Environ. Microbiol. pmid:19047387
Wei P et al. Characterization of two soil metagenome-derived lipases with high specificity for p-nitrophenyl palmitate. 2009 Arch. Microbiol. pmid:19043691
Hiltunen JK et al. Mitochondrial fatty acid synthesis type II: more than just fatty acids. 2009 J. Biol. Chem. pmid:19028688
Sheikh FA et al. Novel self-assembled amphiphilic poly(epsilon-caprolactone)-grafted-poly(vinyl alcohol) nanoparticles: hydrophobic and hydrophilic drugs carrier nanoparticles. 2009 J Mater Sci Mater Med pmid:19020953
Skrivanová E et al. Inhibitory activity of rabbit milk and medium-chain fatty acids against enteropathogenic Escherichia coli O128. 2009 Vet. Microbiol. pmid:19019572
Nobmann P et al. The antimicrobial efficacy and structure activity relationship of novel carbohydrate fatty acid derivatives against Listeria spp. and food spoilage microorganisms. 2009 Int. J. Food Microbiol. pmid:19012983
Miles JM et al. Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion. 1991 Jan-Feb JPEN J Parenter Enteral Nutr pmid:1901106
Walden HR et al. Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway. 2008 Hepatology pmid:19003917
Rossouw D et al. Linking gene regulation and the exo-metabolome: a comparative transcriptomics approach to identify genes that impact on the production of volatile aroma compounds in yeast. 2008 BMC Genomics pmid:18990252
Ding D et al. Yeast bioassay for identification of inositol depleting compounds. 2009 World J. Biol. Psychiatry pmid:18979283
Cabredo-Pinillos S et al. Ultrasound-assisted extraction of volatile compounds from wine samples: optimisation of the method. 2006 Talanta pmid:18970692
Hommelberg PP et al. Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:18957619
Nisly NL et al. Dietary supplement polypharmacy: an unrecognized public health problem? 2010 Evid Based Complement Alternat Med pmid:18955288
Stephenson D and Halpern BP No oral-cavity-only discrimination of purely olfactory odorants. 2009 Chem. Senses pmid:18948567
Ishima Y et al. S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding. 2008 J. Biol. Chem. pmid:18940810
Shenin IuD and Mitrofanova VG [Structure of pentaene antibiotic lavendofuseomycin]. 1991 Antibiot. Khimioter. pmid:1892437
Bhuiyan AK and Pande SV One-step facile synthesis of radioactive acyl-CoA and acylcarnitines using rat liver outer mitochondrial membrane as the enzyme source. 1991 Biochem. Soc. Trans. pmid:1889559
Lumor SE and Akoh CC Esterification and hydrolytic activities of Candida rugosa lipase isoform 1 (LIP1) immobilized on celite 545, duolite A7, and sephadex G-25. 2008 J. Agric. Food Chem. pmid:18850711
Velázquez-Arellano A et al. Functional and metabolic implications of biotin deficiency for the rat heart. 2008 Mol. Genet. Metab. pmid:18824381
Stoddart CA et al. Albumin-conjugated C34 peptide HIV-1 fusion inhibitor: equipotent to C34 and T-20 in vitro with sustained activity in SCID-hu Thy/Liv mice. 2008 J. Biol. Chem. pmid:18809675
Reis P et al. Lipase-catalyzed reactions at interfaces of two-phase systems and microemulsions. 2009 Appl. Biochem. Biotechnol. pmid:18795240
Nogales J et al. A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: iJN746 as a cell factory. 2008 BMC Syst Biol pmid:18793442
Yang JY et al. Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail. 2009 J. Nutr. Biochem. pmid:18789670
Li P et al. Development of clinical dosage forms for a poorly water-soluble drug II: formulation and characterization of a novel solid microemulsion preconcentrate system for oral delivery of a poorly water-soluble drug. 2009 J Pharm Sci pmid:18781639
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Ang WS and Elimelech M Fatty acid fouling of reverse osmosis membranes: implications for wastewater reclamation. 2008 Water Res. pmid:18760439
Hughes RJ et al. A method for collecting breath samples from individual chickens for analysis of 13CO(2), H(2), and CH(4). 2008 Poult. Sci. pmid:18753448
Cheng Y and Hauton D Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase. 2008 Biochim. Biophys. Acta pmid:18722549
Drozak J et al. The inhibition of gluconeogenesis by gatifloxacin may contribute to its hypoglycaemic action. 2008 Eur. J. Pharmacol. pmid:18706903
Vignolo MC et al. Gastric emptying before and after cholecystectomy in patients with cholecystolithiasis. 2008 May-Jun Hepatogastroenterology pmid:18705281
Cordier C et al. Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. 2008 Nat Prod Rep pmid:18663392
Jung Y et al. Application of an elastic biodegradable poly(L-lactide-co-epsilon-caprolactone) scaffold for cartilage tissue regeneration. 2008 J Biomater Sci Polym Ed pmid:18644232
Martin FP et al. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model. 2008 Mol. Syst. Biol. pmid:18628745
Abadi G et al. Naturally occurring esterification reactions with bryostatin. 2008 Nat. Prod. Res. pmid:18626821
Bergmann-Leitner ES et al. Evaluation of immunoglobulin purification methods and their impact on quality and yield of antigen-specific antibodies. 2008 Malar. J. pmid:18625058
Bergeron SJ et al. Saturation transfer double-difference NMR spectroscopy using a dual solenoid microcoil difference probe. 2008 Magn Reson Chem pmid:18615852
Gualillo O et al. Introducing GOAT: a target for obesity and anti-diabetic drugs? 2008 Trends Pharmacol. Sci. pmid:18606462
Feng N et al. Oridonin-loaded poly(epsilon-caprolactone)-poly(ethylene oxide)-poly(epsilon-caprolactone) copolymer nanoparticles: preparation, characterization, and antitumor activity on mice with transplanted hepatoma. 2008 J Drug Target pmid:18604660
Larroche C and Gros JB Batch and continuous 2-heptanone production by Ca-alginate/Eudragit RL entrapped spores of Penicillium roquefortii. 1989 Biotechnol. Bioeng. pmid:18588048
Boyen F et al. Coated fatty acids alter virulence properties of Salmonella Typhimurium and decrease intestinal colonization of pigs. 2008 Vet. Microbiol. pmid:18583068
Ji JH et al. Optimization of octanoic acid and sulfur donor concentrations for lipoic acid production by Pseudomonas reptilivora. 2008 Biotechnol. Lett. pmid:18575810
Takahashi H et al. Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry. 2008 Anal Bioanal Chem pmid:18560811
Panne P et al. Rh-catalyzed intermolecular cyclopropanation with alpha-alkyl-alpha-diazoesters: catalyst-dependent chemo- and diastereoselectivity. 2008 Org. Lett. pmid:18547051
Müller T et al. Entacapone improves absorption of a coadministered salt in patients with Parkinson's disease. 2008 Mov. Disord. pmid:18546331
Morgan-Kiss RM and Cronan JE The Lactococcus lactis FabF fatty acid synthetic enzyme can functionally replace both the FabB and FabF proteins of Escherichia coli and the FabH protein of Lactococcus lactis. 2008 Arch. Microbiol. pmid:18523755
Pendela M et al. Development of a liquid chromatographic method for the determination of related substances and assay of d-cycloserine. 2008 J Pharm Biomed Anal pmid:18514459
Horák T et al. Determination of free medium-chain fatty acids in beer by stir bar sorptive extraction. 2008 J Chromatogr A pmid:18508065
Dietrich B et al. Synthesis, characterization, and high-performance liquid chromatographic evaluation of C14 stationary phases containing branched and unbranched alkyl groups. 2008 Anal Bioanal Chem pmid:18506426
Solis de los Santos F et al. Therapeutic supplementation of caprylic acid in feed reduces Campylobacter jejuni colonization in broiler chicks. 2008 Appl. Environ. Microbiol. pmid:18502935
Maeda A et al. Characterization of novel cholesterol esterase from Trichoderma sp. AS59 with high ability to synthesize steryl esters. 2008 J. Biosci. Bioeng. pmid:18499049
Satapati S et al. Partial resistance to peroxisome proliferator-activated receptor-alpha agonists in ZDF rats is associated with defective hepatic mitochondrial metabolism. 2008 Diabetes pmid:18469201
Koda Y et al. Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. 2008 Bioorg. Med. Chem. pmid:18468445
Hattori Y et al. Gastric emptying rate in subjects with experimentally shortened dental arches: a pilot study. 2008 J Oral Rehabil pmid:18452406
Latere DJ et al. Spontaneously self-assembled micelles from poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylene carbonate) for drug solubilization. 2008 Pharmazie pmid:18444514
Liu S et al. Biological control of phytopathogenic fungi by fatty acids. 2008 Mycopathologia pmid:18443921
Gutierrez JA et al. Ghrelin octanoylation mediated by an orphan lipid transferase. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18443287
Gómez-Valadés AG et al. Pck1 gene silencing in the liver improves glycemia control, insulin sensitivity, and dyslipidemia in db/db mice. 2008 Diabetes pmid:18443203
Gallois M et al. Testing the efficacy of medium chain fatty acids against rabbit colibacillosis. 2008 Vet. Microbiol. pmid:18430526
Yuan MQ et al. Microbial production of medium-chain-length 3-hydroxyalkanoic acids by recombinant Pseudomonas putida KT2442 harboring genes fadL, fadD and phaZ. 2008 FEMS Microbiol. Lett. pmid:18422622
Foschi D et al. Effects of intramural administration of Botulinum Toxin A on gastric emptying and eating capacity in obese patients. 2008 Dig Liver Dis pmid:18420471
Wang S et al. Enhancing effect of Labrafac Lipophile WL 1349 on oral bioavailability of hydroxysafflor yellow A in rats. 2008 Int J Pharm pmid:18417306
Soja GR et al. Temporal evolution of the composition of mixed monolayers on TiO2 surfaces: evidence for a dimerization-induced chelate effect. 2008 Langmuir pmid:18399663
Lockridge JB et al. Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. 2008 J. Lipid Res. pmid:18387886
Du XL et al. 6-Oxy-(acetyl ethylenediamine) fluorescein, a novel fluorescent derivatization reagent for carboxylic acids and its application in HPLC. 2008 J Sep Sci pmid:18381692
Cuomo R et al. Sweetened carbonated drinks do not alter upper digestive tract physiology in healthy subjects. 2008 Neurogastroenterol. Motil. pmid:18373521
Cho CW et al. Development of the ambroxol gels for enhanced transdermal delivery. 2008 Drug Dev Ind Pharm pmid:18363149
Solis de Los Santos F et al. Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens. 2008 Poult. Sci. pmid:18340004
Stucki M et al. Investigations of prion and virus safety of a new liquid IVIG product. 2008 Biologicals pmid:18337119
Choi A et al. The effects of fatty acids in propylene glycol on the percutaneous absorption of alendronate across the excised hairless mouse skin. 2008 Int J Pharm pmid:18329198
Parker KM and Stalcup AM Affinity capillary electrophoresis and isothermal titration calorimetry for the determination of fatty acid binding with beta-cyclodextrin. 2008 J Chromatogr A pmid:18328491
Viegas CA and Sá-Correia I Activation of plasma membrane ATPase of Saccharomyces cerevisiae by octanoic acid. 1991 J. Gen. Microbiol. pmid:1827836
Reine PA et al. Infusion of albumin attenuates changes in serum protein binding of drugs in surgical patients compared with volume replacement with HAES. 2008 Acta Anaesthesiol Scand pmid:18269390
Yang J et al. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. 2008 Cell pmid:18267071
Sobczak M et al. Synthesis and structural analysis of polyester prodrugs of norfloxacin. 2008 Molecules pmid:18259133
Ogawa N et al. The vagal afferent pathway does not play a major role in the induction of satiety by intestinal fatty acid in rats. 2008 Neurosci. Lett. pmid:18248897
Rodrigues F et al. Development of a dynamic headspace solid-phase microextraction procedure coupled to GC-qMSD for evaluation the chemical profile in alcoholic beverages. 2008 Anal. Chim. Acta pmid:18243877
Redwan el-RM et al. Ovine anti-rabies antibody production and evaluation. 2009 Comp. Immunol. Microbiol. Infect. Dis. pmid:18242705
Bailly-Chouriberry L et al. Detection of secondary biomarker of met-eGH as a strategy to screen for somatotropin misuse in horseracing. 2008 Analyst pmid:18227952
Guler JL et al. Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei. 2008 Mol. Microbiol. pmid:18221265
Zulak KG et al. Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures. 2008 BMC Plant Biol. pmid:18211706
Mochizuki K et al. Possible role of fatty acids in milk as the regulator of the expression of cytosolic binding proteins for fatty acids and vitamin A through PPARalpha in developing rats. 2007 J. Nutr. Sci. Vitaminol. pmid:18202540
He B et al. Synthesis and characterization of functionalized biodegradable poly(DL-lactide-co-RS-beta-malic acid). 2008 J Biomed Mater Res A pmid:18181093
James-Smith MA et al. Effect of chain length on binding of fatty acids to Pluronics in microemulsions. 2008 Colloids Surf B Biointerfaces pmid:18155450