octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Sukumar N et al. | Structures of the G81A mutant form of the active chimera of (S)-mandelate dehydrogenase and its complex with two of its substrates. | 2009 | Acta Crystallogr. D Biol. Crystallogr. | pmid:19465768 |
Small RW | An X-ray diffraction study of partially ordered electron density in clathrates of Dianin's compound that include simple carboxylic acids. | 2003 | Acta Crystallogr., B | pmid:12554979 |
Borg LA | Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. | 1981 | Acta Endocrinol. | pmid:7010865 |
Ebbesen F and Brodersen R | Comparison between two preparations of human serum albumin in treatment of neonatal hyperbilirubinaemia. | 1982 | Acta Paediatr Scand | pmid:7136621 |
Brodersen R and Hansen P | Bilirubin displacing effect of stabilizers added to injectable preparations of human serum albumin. | 1977 | Acta Paediatr Scand | pmid:557276 |
Ebbesen F and Brodersen R | Albumin administration combined with phototherapy in treatment of hyperbilirubinaemia in low-birth-weight infants. | 1981 | Acta Paediatr Scand | pmid:7324912 |
Widebäck K | Binding of albumin fragments to surface receptor in A, C, and G streptococci. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:2823527 |
Kinnula VL and Hassinen I | Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart. | 1978 | Acta Physiol. Scand. | pmid:626089 |
Sleboda J et al. | Palmitate oxidation in rat hepatocytes is inhibited by foetal calf serum. | 2001 | Acta Physiol. Scand. | pmid:11736689 |
Kihlberg T et al. | Multiple isotopically labeled fatty acids. 1-11C-2,2',3,3'-tetradeutero palmitic and octanoic acid. | 1991 | Acta Radiol Suppl | pmid:1666733 |
Waldenström A et al. | Myocardial disposition of [1-11C]palmitic acid, 2,2',3,3'-tetradeuteropalmitic acid and octanoic acid in the pig. | 1991 | Acta Radiol Suppl | pmid:1666752 |
Tan CH et al. | Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: antibody production with diagnostic and therapeutic potentials. | 2012 | Acta Trop. | pmid:22322247 |
Omura Y et al. | Caprylic acid in the effective treatment of intractable medical problems of frequent urination, incontinence, chronic upper respiratory infection, root canalled tooth infection, ALS, etc., caused by asbestos & mixed infections of Candida albicans, Helicobacter pylori & cytomegalovirus with or without other microorganisms & mercury. | 2011 | Acupunct Electrother Res | pmid:21830350 |
Liggins RT and Burt HM | Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations. | 2002 | Adv. Drug Deliv. Rev. | pmid:11897145 |
Harris RA et al. | Regulation of branched-chain alpha-ketoacid dehydrogenase complex by covalent modification. | 1986 | Adv. Enzyme Regul. | pmid:3028049 |
el Alaoui-Talibi Z and Moravec J | Limitation of long chain fatty acid oxidation in volume over-loaded rat hearts. | 1989 | Adv. Exp. Med. Biol. | pmid:2506741 |
Phillips JW et al. | Some unexplained features of hepatic ethanol oxidation. | 1985 Jan-Feb | Alcohol | pmid:4015838 |
Derlacz RA et al. | Amino-acid-dependent, differential effects of ethanol on glucose production in rabbit kidney-cortex tubules. | Alcohol Alcohol. | pmid:14998823 | |
Hauser B et al. | Variability of the 13C-octanoic acid breath test for gastric emptying of solids in healthy children. | 2006 | Aliment. Pharmacol. Ther. | pmid:16629936 |
Gourcerol G et al. | Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. | 2015 | Aliment. Pharmacol. Ther. | pmid:25523288 |