octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Redondo O et al. | Comparative kinetic study of lipases A and B from Candida rugosa in the hydrolysis of lipid p-nitrophenyl esters in mixed micelles with Triton X-100. | 1995 | Biochim. Biophys. Acta | pmid:7827103 |
McLaren RD et al. | The use of caprylic acid for the extraction of the immunoglobulin fraction from egg yolk of chickens immunised with ovine alpha-lactalbumin. | 1994 | J. Immunol. Methods | pmid:7822824 |
Garratty G | Problems in pre-transfusion tests related to drugs and chemicals. | 1976 | Am J Med Technol | pmid:779471 |
Maes BD et al. | Influence of octreotide on the gastric emptying of solids and liquids in normal healthy subjects. | 1995 | Aliment. Pharmacol. Ther. | pmid:7766738 |
Berne C | The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies. | 1975 | Biochem. J. | pmid:776173 |
Fryer LG et al. | The long-term regulation of skeletal muscle pyruvate dehydrogenase kinase by dietary lipid is dependent on fatty acid composition. | 1995 | Eur. J. Biochem. | pmid:7758471 |
Pettirossi O et al. | Prolongation of rat heart allograft survival by a synthetic progestogen (melengestrol acetate) and ara-cytidine acylates. | 1976 | Transplantation | pmid:775705 |
Pfaffenbach B et al. | [Non-invasive 13C octanoic acid breath test for measuring stomach emptying of a solid test meal--correlation with scintigraphy in diabetic patients and reproducibility in healthy probands]. | 1995 | Z Gastroenterol | pmid:7754644 |
Svendsen L et al. | Development and comparison of purification strategies for chicken antibodies from egg yolk. | 1995 | Lab. Anim. Sci. | pmid:7752622 |
Martinelle M and Hult K | Kinetics of acyl transfer reactions in organic media catalysed by Candida antarctica lipase B. | 1995 | Biochim. Biophys. Acta | pmid:7669809 |
Sibille B et al. | Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes. | 1995 | Eur. J. Biochem. | pmid:7635161 |
Sarel I and Widmaier EP | Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. | 1995 | Am. J. Physiol. | pmid:7611525 |
Grekin RJ et al. | Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. | 1995 | Hypertension | pmid:7607723 |
Nagatsugi F et al. | 18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution. | 1995 | Chem. Pharm. Bull. | pmid:7600614 |
Duan LP et al. | Influence of cisapride on gastric emptying of solids and liquids monitored by 13C breath tests. | 1995 | Dig. Dis. Sci. | pmid:7587790 |
Onkenhout W et al. | Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. | 1995 | Clin. Chem. | pmid:7586519 |
Yanai S et al. | Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma. | 1995 | Pharm. Res. | pmid:7479548 |
Petcu LG and Plaut GW | NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. | 1980 | Biochem. J. | pmid:7470071 |
Zammit VA | The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. | 1980 | Biochem. J. | pmid:7470052 |
Bartels PD and Sestoft L | Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. | 1980 | Biochim. Biophys. Acta | pmid:7448206 |
Nesher R et al. | Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. | 1980 | Am. J. Physiol. | pmid:7446724 |
Kössler F et al. | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. V. Relations between twitch, tetanus and contracture]. | 1980 | Acta Biol. Med. Ger. | pmid:7445906 |
Hollander D | Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. | 1980 | Am. J. Physiol. | pmid:7435575 |
Waymack PP et al. | Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. | 1980 | J. Biol. Chem. | pmid:7430101 |
Krisans SK et al. | Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. | 1980 | J. Biol. Chem. | pmid:7430088 |
Schenk J et al. | Treatment of choledocholithiasis using the transpapillary perfusion technique. | 1980 | Endoscopy | pmid:7428727 |
Morgenthaler JJ et al. | Fatty acid patterns during plasma fractionation. | 1980 | Vox Sang. | pmid:7415075 |
May ME et al. | Mechanism of the stimulation of branched chain oxoacid oxidation in liver by carnitine. | 1980 | J. Biol. Chem. | pmid:7410370 |
Schenk J et al. | [Irrigation treatment of concrements in the common bile duct with octanoate (Capmul 8210) (author's transl)]. | 1980 | Dtsch. Med. Wochenschr. | pmid:7408673 |
Sugano T et al. | Intracellular redox state and stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused rat liver. | 1980 | J. Biochem. | pmid:7358625 |
Ferré P et al. | Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. | 1981 | Biochem. J. | pmid:7340842 |
Salesse R et al. | [Intensity and anisotropy decays measurement of perylene in pigeon erythrocyte membrane. Comparison with an isotropic viscous medium (author's transl)]. | 1981 Nov-Dec | Biochimie | pmid:7332761 |
Pegg DE et al. | Metabolism of normal and ischemically injured rabbit kidneys during perfusion for 48 hours at 10 C. | 1981 | Transplantation | pmid:7330963 |
Einarsson M et al. | Removal of hepatitis B virus from a concentrate of coagulation factors II, VII, IX and X by hydrophobic interaction chromatography. | 1981 | J. Virol. Methods | pmid:7328163 |
Ebbesen F and Brodersen R | Albumin administration combined with phototherapy in treatment of hyperbilirubinaemia in low-birth-weight infants. | 1981 | Acta Paediatr Scand | pmid:7324912 |
Bauché F et al. | 2-Mercaptoacetate administration depresses the beta-oxidation pathway through an inhibition of long-chain acyl-CoA dehydrogenase activity. | 1981 | Biochem. J. | pmid:7317017 |
Kragh-Hansen U | Effects of aliphatic fatty acids on the binding of Phenol Red to human serum albumin. | 1981 | Biochem. J. | pmid:7316975 |
Balint JA et al. | Desaturation of endogenous and exogenous palmitate in lung tissue in vitro. | 1981 | Lipids | pmid:7300595 |
Nieuwenhuizen W et al. | Purification and properties of two lipases from pig adipose tissue. | 1976 | Biochim. Biophys. Acta | pmid:7300 |
Shigematsu Y et al. | (omega-1)-Hydroxymonocarboxylic acids in urine of infants fed medium-chain triglycerides. | 1981 | Clin. Chem. | pmid:7285316 |
Turakulov IaKh et al. | [Oxidation of palmityl carnitine in mitochondria of rat heart and liver tissue under conditions of thyroid pathology]. | 1981 Mar-Apr | Vopr. Med. Khim. | pmid:7281559 |
Burns AH and Reddy WJ | Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. | 1978 | Am. J. Physiol. | pmid:727249 |
Sumbilla CM et al. | Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:7272339 |
Trauner DA and Adams H | Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. | 1981 | Pediatr. Res. | pmid:7267183 |
Wells JW et al. | The biosynthesis of progesterone by fowl granulosa cells in vitro from 14C-labelled substrates. | 1981 | J. Steroid Biochem. | pmid:7265968 |
Dimenna GP and Emery RS | Palmitate and octanoate metabolism in bovine mammary tissue. | 1981 | J. Dairy Sci. | pmid:7264015 |
Kaler LW and Neaves WB | The steroidogenic capacity of the aging rat testis. | 1981 | J Gerontol | pmid:7252069 |
Rosario P and Medina JM | Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. | 1981 | Rev. Esp. Fisiol. | pmid:7244329 |
Chace KV and Odessey R | The utilization by rabbit aorta of carbohydrates, fatty acids, ketone bodies, and amino acids as substrates for energy production. | 1981 | Circ. Res. | pmid:7226445 |
Parameswaran M and Arinze IJ | Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria. | 1981 | Biochim. Biophys. Acta | pmid:7225415 |