octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thomas JD et al. | The carboxylic and amino acid chemoreception niche of Bulinus rohlfsi (Clessin), the snail host of Schistosoma haematobium. | 1985 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2865079 |
Oberhaensli RD et al. | Effect of norepinephrine on ketogenesis, fatty acid oxidation, and esterification in isolated rat hepatocytes. | 1985 | Diabetes | pmid:2862086 |
Carr C and Morrison DC | Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes. | 1985 | Infect. Immun. | pmid:2989182 |
Remy-Heintz N and Bali JP | [Demonstration of glycoprotein antigens associated with stomach tumors]. | 1985 | C. R. Seances Soc. Biol. Fil. | pmid:2935234 |
Komura S and Kurahashi K | Biosynthesis of polymyxin E by a cell-free enzyme system. IV. Acylation of enzyme-bound L-2,4-diaminobutyric acid. | 1985 | J. Biochem. | pmid:3861608 |
Bjorge SM and Baillie TA | Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3933498 |
Schmidt FH et al. | A new inhibitor of the long-chain fatty acid transfer across the mitochondrial membrane: 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). | 1985 | Life Sci. | pmid:3917523 |
Eanes WF et al. | Targeted selection experiments and enzyme polymorphism: negative evidence for octanoate selection at the G6PD locus in Drosophila melanogaster. | 1985 | Genetics | pmid:3918918 |
Agius L and Alberti KG | Regulation of flux through pyruvate dehydrogenase and pyruvate carboxylase in rat hepatocytes. Effects of fatty acids and glucagon. | 1985 | Eur. J. Biochem. | pmid:3932072 |
Veerkamp JH et al. | Interaction of short-chain and branched-chain fatty acids and their carnitine and CoA esters and of various metabolites and agents with branched-chain 2-oxo acid oxidation in rat muscle and liver mitochondria. | 1985 | Int. J. Biochem. | pmid:3934010 |
Chan K et al. | An improved gas liquid chromatographic assay for plasma valproic acid concentrations in mentally handicapped epileptic children. | 1985 | Methods Find Exp Clin Pharmacol | pmid:3937004 |
Beaufrere B et al. | Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. | 1985 | Am. J. Physiol. | pmid:3895976 |
Duée PH et al. | Development and regulation of ketogenesis in isolated hepatocytes from newborn rabbits. | 1985 | Reprod Nutr Dev | pmid:3992001 |
Lee SM et al. | Prevention of the metabolic effects of 2-tetradecylglycidate by octanoic acid in the genetically diabetic mouse (db/db). | 1985 | Biochem Med | pmid:3994695 |
Sabbagh E et al. | 3-Mercaptopropionic acid, a potent inhibitor of fatty acid oxidation in rat heart mitochondria. | 1985 | J. Biol. Chem. | pmid:3997873 |
Maublant JC et al. | Effects of grisorixin on the distribution of thallium-201 and on the oxidative metabolism in cultured myocardial cells. | 1985 | J. Nucl. Med. | pmid:3998852 |
Bougnères PF et al. | Medium-chain acyl-CoA dehydrogenase deficiency in two siblings with a Reye-like syndrome. | 1985 | J. Pediatr. | pmid:3998948 |
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McCandless DW | Octanoic acid-induced coma and reticular formation energy metabolism. | 1985 | Brain Res. | pmid:4005536 |
Rowley H and Collins RC | [1-14C]Octanoate: a fast functional marker of brain activity. | 1985 | Brain Res. | pmid:4005560 |
Noy N and Zakim D | Substrate specificity of fatty-acyl-CoA ligase in liver microsomes. | 1985 | Biochim. Biophys. Acta | pmid:3970953 |
Germán JC et al. | [Solvent effects on cholesterol calculi: an in vitro study using octanoic acid, glycerol monooctanate, sodium cholate, heparin and ursodeoxycholic acid]. | 1985 | Rev Esp Enferm Apar Dig | pmid:3975461 |
Maddaiah VT | Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3977937 |
Haas R et al. | Salicylate-induced loose coupling: protonmotive force measurements. | 1985 | Biochem. Pharmacol. | pmid:3977963 |
Taylor WM et al. | Effect of depolarizing concentrations of potassium on calcium uptake and metabolism in rat liver. | 1985 | FEBS Lett. | pmid:3979569 |
Brandes R et al. | The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations. | 1985 | Biochim. Biophys. Acta | pmid:4027259 |
Drewes LR and Leino RL | Neuron-specific mitochondrial degeneration induced by hyperammonemia and octanoic acidemia. | 1985 | Brain Res. | pmid:4027650 |
Duran M et al. | Octanoic acidemia and octanoylcarnitine excretion with dicarboxylic aciduria due to defective oxidation of medium-chain fatty acids. | 1985 | J. Pediatr. | pmid:4032135 |
Ferris CF et al. | Alcohol and fatty acid stimulation of neurotensin release from rat small intestine. | 1985 | Endocrinology | pmid:3971900 |
Wolf HP and Engel DW | Decrease of fatty acid oxidation, ketogenesis and gluconeogenesis in isolated perfused rat liver by phenylalkyl oxirane carboxylate (B 807-27) due to inhibition of CPT I (EC 2.3.1.21). | 1985 | Eur. J. Biochem. | pmid:4038486 |
Hütter JF et al. | Effect of fatty acid oxidation on efficiency of energy production in rat heart. | 1985 | Am. J. Physiol. | pmid:4051011 |
Nelis HJ et al. | Chromatographic determination of N-acetyl-DL-tryptophan and octanoic acid in human albumin solutions. | 1985 | J. Chromatogr. | pmid:4055947 |
Zieve L et al. | Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat. | 1985 | J. Lab. Clin. Med. | pmid:4056569 |
Plomp PJ et al. | Mechanism of the stimulation of respiration by fatty acids in rat liver. | 1985 | FEBS Lett. | pmid:4065340 |
MacDonald ML et al. | Aversion of the cat to dietary medium-chain triglycerides and caprylic acid. | 1985 | Physiol. Behav. | pmid:4070410 |
Taguchi S | [Acidosis tolerance of fetal metabolism--comparative studies on isolated perfused adult, fetal and neonatal livers]. | 1985 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:4086906 |
Duran M et al. | Octanoylglucuronide excretion in patients with a defective oxidation of medium-chain fatty acids. | 1985 | Clin. Chim. Acta | pmid:4064333 |
Trauner DA and Garrett RS | Effect of octanoate injection on rat blood-brain barrier. | 1985 Jan-Feb | Pediatr. Neurol. | pmid:3880386 |
Phillips JW et al. | Some unexplained features of hepatic ethanol oxidation. | 1985 Jan-Feb | Alcohol | pmid:4015838 |
Zieve L et al. | Ammonia, octanoate and a mercaptan depress regeneration of normal rat liver after partial hepatectomy. | 1985 Jan-Feb | Hepatology | pmid:3967863 |
Trauner DA and de la Torre JC | Effect of octanoate on blood-brain barrier permeability using L-dopa as a marker. | 1985 Jul-Aug | Pediatr. Neurol. | pmid:3880408 |
Trice JE and Trauner DA | Alterations in serum glucose and hepatic glycogen concentrations during octanoate administration in rabbits. | 1985 Sep-Oct | Pediatr. Neurol. | pmid:3880415 |
Polácek H et al. | Study of cough in anaesthetized cats with experimental pulmonary oedema. | 1986 | Physiol Bohemoslov | pmid:2950532 |
Kössler F et al. | Depressive effects of free fatty acids on the development of tension in different muscle types. | 1986 | Biomed. Biochim. Acta | pmid:2938577 |
Lohse MJ et al. | Effects of temperature and membrane phase transitions on ligand binding to alpha 2-receptors of human platelets. | 1986 | Mol. Pharmacol. | pmid:3005830 |
Taylor WM et al. | The stimulation of tricarboxylic acid-cycle flux by alpha-adrenergic agonists in perfused rat liver. | 1986 | Biochem. J. | pmid:3082324 |
Nomura T et al. | Effects of vasopressin, angiotensin II and phenylephrine on hepatic ketogenesis and fatty acid synthesis. | 1986 | Jpn. J. Pharmacol. | pmid:3773344 |
Yoshioka M et al. | Malabsorption of long-chain fatty acid in cholera toxin-induced secretory diarrhea. | 1986 | Dig. Dis. Sci. | pmid:3698768 |
Beuers U et al. | Control of ketogenesis in the perfused rat liver by the sympathetic innervation. | 1986 | Eur. J. Biochem. | pmid:3732268 |
Connolly E et al. | Norepinephrine-induced Na+ influx in brown adipocytes is cyclic AMP-mediated. | 1986 | J. Biol. Chem. | pmid:3021738 |