octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Trauner DA and Huttenlocher PR | Short chain fatty acid-induced central hyperventilation in rabbits. | 1978 | Neurology | pmid:567765 |
Demol P and Sarles H | Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. | 1978 | J. Physiol. (Lond.) | pmid:633115 |
Hansford RG | Lipid oxidation by heart mitochondria from young adult and senescent rats. | 1978 | Biochem. J. | pmid:637843 |
Meisner H and Neet K | Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. | 1978 | Mol. Pharmacol. | pmid:642932 |
Mannaerts GP et al. | Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. | 1978 | Biochim. Biophys. Acta | pmid:656451 |
Scholz R et al. | The effect of fatty acids on the regulation of pyruvate dehydrogenase in perfused rat liver. | 1978 | Eur. J. Biochem. | pmid:658055 |
Burns AH and Reddy WJ | Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. | 1978 | Am. J. Physiol. | pmid:727249 |
Fildes FJ and Oliver JE | Interaction of cortisol-21-palmitate with liposomes examined by differential scanning calorimetry. | 1978 | J. Pharm. Pharmacol. | pmid:26761 |
Sheikh MI et al. | On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. | 1978 | Arch. Int. Physiol. Biochim. | pmid:87158 |
Rabinowitz JL et al. | The effects of intravenous sodium octanoate on the rhesus monkey. | 1978 | Am. J. Gastroenterol. | pmid:96693 |
Agostini C | Effect of sodium octanoate on leucine incorporation into protein of rat liver slices and of Yoshida ascites hepatoma cells. | 1978 | Experientia | pmid:203476 |
Miller TB | Cardiac performance of isolated perfused hearts from alloxan diabetic rats. | 1979 | Am. J. Physiol. | pmid:443443 |
Hulshoff A and Roseboom H | Determination of valproic acid (di-N-propyl acetic acid) in plasma by gas-liquid chromatography with pre-column butylation. | 1979 | Clin. Chim. Acta | pmid:373927 |
Skrede S and Slaattelid O | Fatty acid metabolism during hypothermic perfusion of the isolated dog kidney. | 1979 | Scand. J. Clin. Lab. Invest. | pmid:531496 |
Schröder K et al. | [Energy metabolism of the rat renal cortex, as measured by incubation in various substrates]. | 1979 | Acta Biol. Med. Ger. | pmid:543370 |
Staeffen J et al. | [Hyperoctanoatemia and the hepatic encephalopathy of cirrhosis. 150 dosages in 61 patients (author's transl)]. | 1979 | Nouv Presse Med | pmid:112576 |
Fischer JH et al. | Free fatty acid and glucose metabolism during hypothermic perfusion of canine kidneys. | 1979 | Eur Surg Res | pmid:488147 |
Lemieux G et al. | Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. | 1979 | Am. J. Physiol. | pmid:464062 |
Spydevold O | The effect of octanoate and palmitate on the metabolism of valine in perfused hindquarter of rat. | 1979 | Eur. J. Biochem. | pmid:467425 |
Tanner GA et al. | Excretion of phenol red by the Necturus kidney. | 1979 | Am. J. Physiol. | pmid:443381 |