octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
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Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
| Sumbilla CM et al. | Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. | 1981 | Biochim. Biophys. Acta | pmid:7272339 |
| Einarsson R | The binding of 1-anilino-8-naphthalenesulfonate, heparin, salicylate and caprylate by human antithrombin III. | 1976 | Biochim. Biophys. Acta | pmid:974107 |
| Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
| Ayuso MS et al. | Interrelation between gluconeogenesis and hepatic protein synthesis. | 1986 | Biochim. Biophys. Acta | pmid:3015233 |
| Tachibana S et al. | Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes. | 2005 | Biochim. Biophys. Acta | pmid:16226916 |
| Arakawa T and Kita Y | Stabilizing effects of caprylate and acetyltryptophanate on heat-induced aggregation of bovine serum albumin. | 2000 | Biochim. Biophys. Acta | pmid:10862953 |
| Veerkamp JH et al. | An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. | 1986 | Biochim. Biophys. Acta | pmid:3081042 |
| GLENN JL et al. | Rare-earth fatty liver. I. Octanoate oxidation and energy production. | 1962 | Biochim. Biophys. Acta | pmid:13899206 |
| Barron JT et al. | Effect of serum albumin on vascular smooth muscle metabolism. | 2000 | Biochim. Biophys. Acta | pmid:10924897 |
| DIANZANI MU and MARINARI U | The octanoate oxidation by mitochondria from faty livers. | 1961 | Biochim. Biophys. Acta | pmid:13722612 |
| Herold G et al. | Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. | 1984 | Biochim. Biophys. Acta | pmid:6567470 |
| Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
| Gambert S et al. | Regulation of intermediary metabolism in rat cardiac myocyte by extracellular glycerol. | 2005 | Biochim. Biophys. Acta | pmid:16153888 |
| Cheng Y and Hauton D | Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase. | 2008 | Biochim. Biophys. Acta | pmid:18722549 |
| Müller MJ et al. | Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. | 1981 | Biochim. Biophys. Acta | pmid:6275888 |
| Anraku M et al. | Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress. | 2004 | Biochim. Biophys. Acta | pmid:15450846 |
| Martinelle M and Hult K | Kinetics of acyl transfer reactions in organic media catalysed by Candida antarctica lipase B. | 1995 | Biochim. Biophys. Acta | pmid:7669809 |
| Hulsmann WC et al. | Imminent ischemia in normal and hypertrophic Langendorff rat hearts; effects of fatty acids and superoxide dismutase monitored by NADH surface fluorescence. | 1993 | Biochim. Biophys. Acta | pmid:8318552 |
| Viegas CA et al. | Regulation of the expression of the H(+)-ATPase genes PMA1 and PMA2 during growth and effects of octanoic acid in Saccharomyces cerevisiae. | 1994 | Biochim. Biophys. Acta | pmid:8286419 |
| Murphy MG et al. | Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy. | 1996 | Biochim. Biophys. Acta | pmid:8611661 |
| Decagny B et al. | 1H-NMR on line monitoring of water activity during lipase catalysed esterification. | 1998 | Biochim. Biophys. Acta | pmid:9748540 |
| Brandes R et al. | The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations. | 1985 | Biochim. Biophys. Acta | pmid:4027259 |
| Thennarasu S et al. | Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843. | 2005 | Biochim. Biophys. Acta | pmid:15904663 |
| Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
| Magliano P et al. | Repercussion of a deficiency in mitochondrial ß-oxidation on the carbon flux of short-chain fatty acids to the peroxisomal ß-oxidation cycle in Aspergillus nidulans. | 2010 | Biochim. Biophys. Acta | pmid:20736083 |
| Shimshoni JA et al. | Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder. | 2011 | Biochim. Biophys. Acta | pmid:21184843 |
| Nomura T et al. | Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. | 1983 | Biochim. Biophys. Acta | pmid:6317044 |
| Salesse R et al. | [Intensity and anisotropy decays measurement of perylene in pigeon erythrocyte membrane. Comparison with an isotropic viscous medium (author's transl)]. | 1981 Nov-Dec | Biochimie | pmid:7332761 |
| Pérez-Diaz J et al. | Preparation and metabolic characterization of isolated rat lung cells. | 1977 | Biochimie | pmid:195638 |
| Pochapsky SS et al. | Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. | 1990 Jul-Aug | Bioconjug. Chem. | pmid:2096916 |
| van Ginkel CG et al. | Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. | 2008 | Biodegradation | pmid:17492358 |
| Goussen C et al. | Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. | 2017 | BioDrugs | pmid:28508264 |
| Nagata J et al. | Effects of structured lipids containing eicosapentaenoic or docosahexaenoic acid and caprylic acid on serum and liver lipid profiles in rats. | 2004 | Biofactors | pmid:15630273 |
| Kundu S and Roy D | Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. | 2010 | Bioinformation | pmid:20978606 |
| Kumar S | Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. | 2011 | Bioinformation | pmid:22355237 |
| Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
| Lemmen C et al. | Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts. | 1988 | Biol. Chem. Hoppe-Seyler | pmid:3242549 |
| Küster J et al. | Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. | 1989 | Biol. Chem. Hoppe-Seyler | pmid:2692615 |
| Kuge Y et al. | [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. | 2000 | Biol. Pharm. Bull. | pmid:10963308 |
| Tokudome Y and Otsuka M | Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. | 2012 | Biol. Pharm. Bull. | pmid:22975500 |
| Uchida M and Shimizu K | 13C-acetic acid is more sensitive than 13C-octanoic acid for evaluating gastric emptying of liquid enteral nutrient formula by breath test in conscious rats. | 2007 | Biol. Pharm. Bull. | pmid:17329843 |
| Solano S et al. | Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. | 2012 | Biologicals | pmid:22266304 |
| Johnston A et al. | Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. | 2003 | Biologicals | pmid:12935811 |
| Segura A et al. | Assessment of the impact of solvent/detergent treatment on the quality and potency of a whole IgG equine antivenom. | 2009 | Biologicals | pmid:19540775 |
| Mpandi M et al. | Partitioning and inactivation of viruses by the caprylic acid precipitation followed by a terminal pasteurization in the manufacturing process of horse immunoglobulins. | 2007 | Biologicals | pmid:17470396 |
| Burnouf T et al. | Assessment of viral inactivation during pH 3.3 pepsin digestion and caprylic acid treatment of antivenoms. | 2007 | Biologicals | pmid:17363271 |
| Simsiriwong P et al. | A study on the use of caprylic acid and ammonium sulfate in combination for the fractionation of equine antivenom F(ab')(2). | 2012 | Biologicals | pmid:22704919 |
| GarcÃa M et al. | Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. | 2002 | Biologicals | pmid:12127316 |
| Korneyeva M et al. | Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates. | 2002 | Biologicals | pmid:12127317 |