octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rhead WJ et al. | Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. | 1983 | Science | pmid:6857268 |
Plante OJ et al. | Automated solid-phase synthesis of oligosaccharides. | 2001 | Science | pmid:11222853 |
Yamada M et al. | A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. | 2012 | Sci Rep | pmid:23226596 |
Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |
Zimmermann S et al. | Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. | 2012 Jan-Mar | Sci Pharm | pmid:22396915 |
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Hope HB et al. | Reduced ¹³C-D-xylose absorption in alcoholics is more likely caused by alterations in small intestinal mucosa than delayed gastric emptying. | 2011 | Scand. J. Gastroenterol. | pmid:21275757 |
Sugiyama E et al. | Desirable pharmacokinetic properties of (13)C-uracil as a breath test probe of gastric emptying in comparison with (13)C-acetate and (13)C-octanoate in rats. | 2009 | Scand. J. Gastroenterol. | pmid:19585373 |
Skrede S and Slaattelid O | Fatty acid metabolism during hypothermic perfusion of the isolated dog kidney. | 1979 | Scand. J. Clin. Lab. Invest. | pmid:531496 |