octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Carr C and Morrison DC | Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes. | 1985 | Infect. Immun. | pmid:2989182 |
Remy-Heintz N and Bali JP | [Demonstration of glycoprotein antigens associated with stomach tumors]. | 1985 | C. R. Seances Soc. Biol. Fil. | pmid:2935234 |
Schmidt FH et al. | A new inhibitor of the long-chain fatty acid transfer across the mitochondrial membrane: 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). | 1985 | Life Sci. | pmid:3917523 |
Eanes WF et al. | Targeted selection experiments and enzyme polymorphism: negative evidence for octanoate selection at the G6PD locus in Drosophila melanogaster. | 1985 | Genetics | pmid:3918918 |
Ferris CF et al. | Alcohol and fatty acid stimulation of neurotensin release from rat small intestine. | 1985 | Endocrinology | pmid:3971900 |
Lutz WH et al. | Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides. | 1985 | Biochem Med | pmid:4052056 |
Strieleman PJ et al. | Fatty acid activation of the reconstituted brown adipose tissue mitochondria uncoupling protein. | 1985 | J. Biol. Chem. | pmid:4055740 |
Nelis HJ et al. | Chromatographic determination of N-acetyl-DL-tryptophan and octanoic acid in human albumin solutions. | 1985 | J. Chromatogr. | pmid:4055947 |
Zieve L et al. | Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat. | 1985 | J. Lab. Clin. Med. | pmid:4056569 |
Plomp PJ et al. | Mechanism of the stimulation of respiration by fatty acids in rat liver. | 1985 | FEBS Lett. | pmid:4065340 |
MacDonald ML et al. | Aversion of the cat to dietary medium-chain triglycerides and caprylic acid. | 1985 | Physiol. Behav. | pmid:4070410 |
Taguchi S | [Acidosis tolerance of fetal metabolism--comparative studies on isolated perfused adult, fetal and neonatal livers]. | 1985 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:4086906 |
Allen PC | Physiological responses of chicken gut tissue to infection with Eimeria acervulina. | 1984 Oct-Dec | Avian Dis. | pmid:6441557 |
Pfadenhauer EH et al. | Identification of the metabolites of erythro-9-(2-hydroxy-3-nonyl)hypoxanthine from laboratory animals. | 1984 May-Jun | Drug Metab. Dispos. | pmid:6145553 |
Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
Otto DA | Relationship of the ATP/ADP ratio to the site of octanoate activation. | 1984 | J. Biol. Chem. | pmid:6715356 |
Blumenthal SA | Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action. | 1984 | Biochem. J. | pmid:6430273 |
Duran M et al. | The differential diagnosis of dicarboxylic aciduria. | 1984 | J. Inherit. Metab. Dis. | pmid:6434845 |
Riecken EO | [Structural and functional findings in experimental blind loop syndrome]. | 1984 | Nahrung | pmid:6493325 |
Buxton DB et al. | Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart. | 1984 | Biochem. J. | pmid:6477487 |
Kim CS et al. | L-carnitine: therapeutic strategy for metabolic encephalopathy. | 1984 | Brain Res. | pmid:6478235 |
Wagenmakers AJ et al. | Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation. | 1984 | Biochem. J. | pmid:6517861 |
Schönfeld P et al. | Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. | 1984 | Biomed. Biochim. Acta | pmid:6525184 |
Pappas SC et al. | Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. | 1984 | Gastroenterology | pmid:6693016 |
Kohlwein SD and Paltauf F | Uptake of fatty acids by the yeasts, Saccharomyces uvarum and Saccharomycopsis lipolytica. | 1984 | Biochim. Biophys. Acta | pmid:6696936 |
Bell FP | Di(2-ethylhexyl)adipate (DEHA): effect on plasma lipids and hepatic cholesterolgenesis in the rat. | 1984 | Bull Environ Contam Toxicol | pmid:6697017 |
Nauclér J et al. | Evaluation of kidney viability during hypothermic perfusion or cold storage. | 1984 | Eur Surg Res | pmid:6698069 |
Silavin SL et al. | Reevaluation of the effects of cytochalasins on steroidogenesis: studies on hamster granulosa cells. | 1984 | Endocrinology | pmid:6592092 |
Pösö AR and Mortimore GE | Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6589593 |
Herold G et al. | Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. | 1984 | Biochim. Biophys. Acta | pmid:6567470 |
Martin-Sanz P et al. | Long-chain fatty acids and their acyl-CoA esters cause the translocation of phosphatidate phosphohydrolase from the cytosolic to the microsomal fraction of rat liver. | 1984 | FEBS Lett. | pmid:6090213 |
Sundin U et al. | Thyroid-catecholamine interactions in isolated rat brown adipocytes. | 1984 | Metab. Clin. Exp. | pmid:6092828 |
Baraldi M et al. | Toxins in hepatic encephalopathy: the role of the synergistic effect of ammonia, mercaptans and short chain fatty acids. | 1984 | Arch. Toxicol. Suppl. | pmid:6097201 |
Claycomb WC et al. | Culture of the terminally differentiated ventricular cardiac muscle cell. Characterization of exogenous substrate oxidation and the adenylate cyclase system. | 1984 | FEBS Lett. | pmid:6201398 |
White RH | The biosynthesis of n-[(2)H (7)] fatty acids byArthrobacter globiformis from [U-(2)H (15)] octanoic acid. | 1984 | Lipids | pmid:21344284 |
Yu MW and Finlayson JS | Quantitative determination of the stabilizers octanoic acid and N-acetyl-DL-tryptophan in human albumin products. | 1984 | J Pharm Sci | pmid:6694090 |
Chen V et al. | Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. | 1984 | Horm. Metab. Res. | pmid:6735347 |
Ross PD et al. | Thermal stability of human albumin measured by differential scanning calorimetry. II. Effects of isomers of N-acetyltryptophanate and tryptophanate, pH, reheating, and dimerization. | 1984 | Vox Sang. | pmid:6741029 |
Yu MW and Finlayson JS | Stabilization of human albumin by caprylate and acetyltryptophanate. | 1984 | Vox Sang. | pmid:6741030 |
Shrake A et al. | Thermal stability of human albumin measured by differential scanning calorimetry. I. Effects of caprylate and N-acetyltryptophanate. | 1984 | Vox Sang. | pmid:6741034 |
Soboll S et al. | Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. | 1984 | Biochem. J. | pmid:6743276 |
Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
Thayer WS | Inhibition of mitochondrial fatty acid oxidation in pentenoic acid-induced fatty liver. A possible model for Reye's syndrome. | 1984 | Biochem. Pharmacol. | pmid:6712730 |
Habeeb AF and Francis RD | Preparation of human immunoglobulin by caprylic acid precipitation. | 1984 | Prep. Biochem. | pmid:6718324 |
Reed WD et al. | A double-isotope method for the measurement of ketone-body turnover in the rat. Effect of L-alanine. | 1984 | Biochem. J. | pmid:6721850 |
Soboll S et al. | Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6723661 |
Aurousseau B et al. | [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. | 1984 | Reprod Nutr Dev | pmid:6729239 |
Katoh K and Tsuda T | Effects of acetylcholine and short-chain fatty acids on acinar cells of the exocrine pancreas in sheep. | 1984 | J. Physiol. (Lond.) | pmid:6084059 |
Kochel PJ et al. | Effects of noncarbohydrate substrates on protein synthesis in hearts from fed and fasted rats. | 1984 | J. Mol. Cell. Cardiol. | pmid:6374161 |
Reed WD et al. | The effects of insulin and glucagon on ketone-body turnover. | 1984 | Biochem. J. | pmid:6383348 |