octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rosario P and Medina JM | Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. | 1980 | Rev. Esp. Fisiol. | pmid:7221165 |
Carrington MJ et al. | Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. | 1981 | Biochem. Soc. Trans. | pmid:7215663 |
Seydoux J et al. | Functional disconnection of brown adipose tissue in hypothalamic obesity in rats. | 1981 | Pflugers Arch. | pmid:7195549 |
Weight MJ et al. | Cholesterol-ascorbic acid interactions in guinea pig liver homogenates, and in the in situ perfused liver: relationship between ascorbic acid status and cholesterol and bile acid synthesis from mevalonate. | 1982 | Int J Vitam Nutr Res | pmid:7174228 |
Shipp DA et al. | Development of fatty acid oxidation in neonatal guinea-pig liver. | 1982 | Biochem. J. | pmid:7165728 |
Reuge C | [Enzymatic determination of caprylates in protein preparations]. | 1982 | Rev. Fr. Transfus. Immunohematol. | pmid:7163732 |
Roeder LM et al. | The effects of ketone bodies, bicarbonate, and calcium on hepatic mitochondrial ketogenesis. | 1982 | Arch. Biochem. Biophys. | pmid:7138017 |
Ebbesen F and Brodersen R | Comparison between two preparations of human serum albumin in treatment of neonatal hyperbilirubinaemia. | 1982 | Acta Paediatr Scand | pmid:7136621 |
Sugano T et al. | Stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused chicken liver. | 1982 | J. Biochem. | pmid:7118865 |
Sugano T et al. | Intracellular redox state and control of gluconeogenesis in perfused chicken liver. | 1982 | J. Biochem. | pmid:7118853 |
Zeneroli ML et al. | Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid. | 1982 Sep-Oct | Hepatology | pmid:7118066 |
Garcia-Esteller SC et al. | Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo. | 1982 | Int. J. Biochem. | pmid:7106360 |
Odessey R and Chace KV | Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. | 1982 | Am. J. Physiol. | pmid:7091374 |
Haidukewych D et al. | Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet. | 1982 | Clin. Chem. | pmid:7074833 |
Zwiebel FM et al. | Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. | 1982 | Biochemistry | pmid:7074018 |
Borg LA | Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. | 1981 | Acta Endocrinol. | pmid:7010865 |
Barth CA et al. | Morphology and metabolism of adult rat hepatocytes in primary culture. | 1980 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6997170 |
Caffier G et al. | Contractile properties of isolated frog skeletal muscles under the influence of Na-octanoate. | 1982 | Acta Biol. Med. Ger. | pmid:6981273 |
Caffier G and Küchler G | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. | 1980 | Acta Biol. Med. Ger. | pmid:6969509 |
Kössler F et al. | Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. | 1980 | Chem. Biol. Interact. | pmid:6967777 |