octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mannaerts GP et al. | Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. | 1978 | Biochim. Biophys. Acta | pmid:656451 |
Allen PC and Danforth HD | The effects of Eimeria acervulina infection on the metabolism of chick duodenal tissue. | 1984 | Vet. Parasitol. | pmid:6538718 |
Schönfeld P et al. | Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. | 1984 | Biomed. Biochim. Acta | pmid:6525184 |
Wagenmakers AJ et al. | Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation. | 1984 | Biochem. J. | pmid:6517861 |
Riecken EO | [Structural and functional findings in experimental blind loop syndrome]. | 1984 | Nahrung | pmid:6493325 |
Zieve L et al. | Brain methanethiol and ammonia concentrations in experimental hepatic coma and coma induced by injections of various combinations of these substances. | 1984 | J. Lab. Clin. Med. | pmid:6491466 |
Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
Kim CS et al. | L-carnitine: therapeutic strategy for metabolic encephalopathy. | 1984 | Brain Res. | pmid:6478235 |
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Felix R and Fleisch H | Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates. | 1981 | Biochem. J. | pmid:6458286 |
Allen PC | Physiological responses of chicken gut tissue to infection with Eimeria acervulina. | 1984 Oct-Dec | Avian Dis. | pmid:6441557 |
Schudt C and Simon A | Effects of sodium 2-[5-(4-chlorophenyl)pentyl]-oxirane-2-carboxylate (POCA) on carbohydrate and fatty acid metabolism in liver and muscle. | 1984 | Biochem. Pharmacol. | pmid:6437406 |
Duran M et al. | The differential diagnosis of dicarboxylic aciduria. | 1984 | J. Inherit. Metab. Dis. | pmid:6434845 |
Blumenthal SA | Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action. | 1984 | Biochem. J. | pmid:6430273 |
Meisner H and Neet K | Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. | 1978 | Mol. Pharmacol. | pmid:642932 |
Scholz R et al. | Influence of fatty acids on energy metabolism. 1. Stimulation of oxygen consumption, ketogenesis and CO2 production following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6426957 |
Hampson RK et al. | Regulation of the glycine cleavage system in the isolated perfused rat liver. | 1984 | J. Biol. Chem. | pmid:6420402 |
Nagi MN et al. | Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase. | 1983 | Arch. Biochem. Biophys. | pmid:6416174 |
McDonough KH and Spitzer JJ | Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. | 1983 | Proc. Soc. Exp. Biol. Med. | pmid:6412237 |
Becker CM and Harris RA | Influence of valproic acid on hepatic carbohydrate and lipid metabolism. | 1983 | Arch. Biochem. Biophys. | pmid:6407400 |