octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Crohn Disease D003424 12 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Starvation D013217 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Schistosomiasis D012552 4 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Liver Failure D017093 5 associated lipids
Chickenpox D002644 1 associated lipids
Chylothorax D002916 1 associated lipids
Gastroparesis D018589 2 associated lipids
Gallstones D042882 3 associated lipids
Dyspepsia D004415 5 associated lipids
Snake Bites D012909 1 associated lipids
Prion Diseases D017096 2 associated lipids
Asthenia D001247 5 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Essential Tremor D020329 2 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Giardiasis D005873 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Du JZ et al. Synthesis and characterization of photo-cross-linked hydrogels based on biodegradable polyphosphoesters and poly(ethylene glycol) copolymers. 2007 Biomacromolecules pmid:17902689
Kojima M and Kangawa K [Structure and function of ghrelin]. 2007 Seikagaku pmid:17969325
Allard MF et al. AMPK and metabolic adaptation by the heart to pressure overload. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:16920812
Nohara S et al. Gastric emptying in patients with Type 2 diabetes mellitus and diabetes associated with mitochondrial DNA 3243 mutation using 13C-octanoic acid breath test. 2006 Sep-Oct J. Diabetes Complicat. pmid:16949516
Müller T et al. Impact of gastric emptying on levodopa pharmacokinetics in Parkinson disease patients. 2006 Mar-Apr Clin Neuropharmacol pmid:16614536
Samant MP et al. Novel analogues of degarelix incorporating hydroxy-, methoxy-, and pegylated-urea moieties at positions 3, 5, 6 and the N-terminus. Part III. 2006 J. Med. Chem. pmid:16759096
Iwahashi H et al. High performance liquid chromatography/electron spin resonance/mass spectrometry analyses of radicals formed in an anaerobic reaction of 9- (or 13-) hydroperoxide octadecadienoic acids with ferrous ions. 2006 J Chromatogr A pmid:16889785
Martin JD et al. Structure and membrane affinity of new amphiphilic siderophores produced by Ochrobactrum sp. SP18. 2006 J. Biol. Inorg. Chem. pmid:16791646
Jambor de Sousa UL et al. Caprylic acid infusion acts in the liver to decrease food intake in rats. 2006 Physiol. Behav. pmid:16360711
Iram SH and Cronan JE The beta-oxidation systems of Escherichia coli and Salmonella enterica are not functionally equivalent. 2006 J. Bacteriol. pmid:16385050
Shrake A et al. Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions. 2006 Biopolymers pmid:16273515
Delamarre SC and Batt CA Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha. 2006 Appl. Microbiol. Biotechnol. pmid:16362422
Vinson SB et al. Nest liquid resources of several cavity nesting bees in the genus Centris and the identification of a preservative, levulinic acid. 2006 J. Chem. Ecol. pmid:16902822
Amalaradjou MA et al. Inactivation of escherichia coli O157:H7 in cattle drinking water by sodium caprylate. 2006 J. Food Prot. pmid:16995532
Darnell ME and Taylor DR Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products. 2006 Transfusion pmid:17002634
Sanaka M et al. Assessment of the gastric emptying velocity by the 13C-octanoate breath test: deconvolution versus a Wagner-Nelson analysis. 2006 J. Gastroenterol. pmid:16933000
Bryant P et al. The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate. 2006 Anal. Biochem. pmid:16500612
Parkkinen J et al. A modified caprylic acid method for manufacturing immunoglobulin G from human plasma with high yield and efficient virus clearance. 2006 Vox Sang. pmid:16430667
Ayub ND et al. Impaired polyhydroxybutyrate biosynthesis from glucose in Pseudomonas sp. 14-3 is due to a defective beta-ketothiolase gene. 2006 FEMS Microbiol. Lett. pmid:17020558
Moechars D et al. Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse. 2006 Gastroenterology pmid:17030183
Che CM et al. Ruthenium-catalyzed oxidation of alkenes, alkynes, and alcohols to organic acids with aqueous hydrogen peroxide. 2006 Chem Asian J pmid:17441082
Redwan el-RM Comparison between therapeutic antitoxin F(ab)2 fractionated with ammonium sulfate and caprylic acid. 2006 J Immunoassay Immunochem pmid:16981645
Sanaka M et al. Is the time for absorption and oxidation of 13c-octanoate really negligible in the gastric emptying breath test? 2006 Dig. Dis. Sci. pmid:17120146
Jones PM et al. Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts. 2006 Biochem. Biophys. Res. Commun. pmid:16750167
Bouvet L et al. Erythromycin promotes gastric emptying during acute pain in volunteers. 2006 Anesth. Analg. pmid:16717329
Otero R et al. Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia. 2006 Trans. R. Soc. Trop. Med. Hyg. pmid:16698053
Vanden Heuvel JP et al. Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. 2006 Toxicol. Sci. pmid:16731579
Wilson TA et al. Structured triglycerides containing caprylic (8:0) and oleic (18:1) fatty acids reduce blood cholesterol concentrations and aortic cholesterol accumulation in hamsters. 2006 Biochim. Biophys. Acta pmid:16580874
Kachi M et al. Effects of Helicobacter pylori eradication therapy on gastric emptying measured using the 13C-octanoic acid breath test and the acetaminophen method. 2006 J. Gastroenterol. Hepatol. pmid:16704530
De Smet B et al. Energy homeostasis and gastric emptying in ghrelin knockout mice. 2006 J. Pharmacol. Exp. Ther. pmid:16203827
Li YH et al. [Effects of absorption enhancers on intestinal absorption of lumbrokinase]. 2006 Yao Xue Xue Bao pmid:17184110
Conte E et al. Regulation of polyhydroxyalkanoate synthases (phaC1 and phaC2) gene expression in Pseudomonas corrugata. 2006 Appl. Microbiol. Biotechnol. pmid:16607528
Tao F et al. Competition and coadsorption of di-acids and carboxylic acid solvents on HOPG. 2006 J Phys Chem B pmid:17004820
Hellmig S et al. Gastric emptying time of fluids and solids in healthy subjects determined by 13C breath tests: influence of age, sex and body mass index. 2006 J. Gastroenterol. Hepatol. pmid:17074022
Davaran S et al. Adriamycin release from poly(lactide-coglycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization. 2006 Int J Nanomedicine pmid:17722284
Guo W et al. Modulation of adipocyte lipogenesis by octanoate: involvement of reactive oxygen species. 2006 Nutr Metab (Lond) pmid:16872526
Kragh-Hansen U et al. Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis. 2006 J. Mol. Biol. pmid:16979183
Thorburn MS et al. Attenuated gastric distress but no benefit to performance with adaptation to octanoate-rich esterified oils in well-trained male cyclists. 2006 J. Appl. Physiol. pmid:16840580
Brill J et al. Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami. 2006 J. Neurosci. pmid:16793888
Gerhardt WW et al. Functional lactide monomers: methodology and polymerization. 2006 Biomacromolecules pmid:16768392
Aydin HM et al. Attachment and growth of fibroblasts on poly(L-lactide/epsilon-caprolactone) scaffolds prepared in supercritical CO2 and modified by polyethylene imine grafting with ethylene diamine-plasma in a glow-discharge apparatus. 2006 Int J Artif Organs pmid:17033995
Gasbarrini G et al. Evaluation of thermal water in patients with functional dyspepsia and irritable bowel syndrome accompanying constipation. 2006 World J. Gastroenterol. pmid:16688801
Hosoda H et al. Biological, physiological, and pharmacological aspects of ghrelin. 2006 J. Pharmacol. Sci. pmid:16612045
Puigmartí-Luis J et al. Noncovalent control for bottom-up assembly of functional supramolecular wires. 2006 J. Am. Chem. Soc. pmid:17002326
Elluru S et al. Comparative study of the anti-inflammatory effect of two intravenous immunoglobulin preparations manufactured by different processes. 2006 Immunol. Lett. pmid:16952403
Gil-Campos M et al. Ghrelin: a hormone regulating food intake and energy homeostasis. 2006 Br. J. Nutr. pmid:16923214
Jiang Y et al. The soluble acyl-acyl carrier protein synthetase of Vibrio harveyi B392 is a member of the medium chain acyl-CoA synthetase family. 2006 Biochemistry pmid:16906759
Matulka RA et al. Safety evaluation of a medium- and long-chain triacylglycerol oil produced from medium-chain triacylglycerols and edible vegetable oil. 2006 Food Chem. Toxicol. pmid:16753249
Hartmann R et al. Tailor-made olefinic medium-chain-length poly[(R)-3-hydroxyalkanoates] by Pseudomonas putida GPo1: batch versus chemostat production. 2006 Biotechnol. Bioeng. pmid:16255038
Wang J et al. Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers. 2006 Peptides pmid:16242213