octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Du JZ et al. | Synthesis and characterization of photo-cross-linked hydrogels based on biodegradable polyphosphoesters and poly(ethylene glycol) copolymers. | 2007 | Biomacromolecules | pmid:17902689 |
Kojima M and Kangawa K | [Structure and function of ghrelin]. | 2007 | Seikagaku | pmid:17969325 |
Allard MF et al. | AMPK and metabolic adaptation by the heart to pressure overload. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16920812 |
Nohara S et al. | Gastric emptying in patients with Type 2 diabetes mellitus and diabetes associated with mitochondrial DNA 3243 mutation using 13C-octanoic acid breath test. | 2006 Sep-Oct | J. Diabetes Complicat. | pmid:16949516 |
Müller T et al. | Impact of gastric emptying on levodopa pharmacokinetics in Parkinson disease patients. | 2006 Mar-Apr | Clin Neuropharmacol | pmid:16614536 |
Samant MP et al. | Novel analogues of degarelix incorporating hydroxy-, methoxy-, and pegylated-urea moieties at positions 3, 5, 6 and the N-terminus. Part III. | 2006 | J. Med. Chem. | pmid:16759096 |
Iwahashi H et al. | High performance liquid chromatography/electron spin resonance/mass spectrometry analyses of radicals formed in an anaerobic reaction of 9- (or 13-) hydroperoxide octadecadienoic acids with ferrous ions. | 2006 | J Chromatogr A | pmid:16889785 |
Martin JD et al. | Structure and membrane affinity of new amphiphilic siderophores produced by Ochrobactrum sp. SP18. | 2006 | J. Biol. Inorg. Chem. | pmid:16791646 |
Jambor de Sousa UL et al. | Caprylic acid infusion acts in the liver to decrease food intake in rats. | 2006 | Physiol. Behav. | pmid:16360711 |
Iram SH and Cronan JE | The beta-oxidation systems of Escherichia coli and Salmonella enterica are not functionally equivalent. | 2006 | J. Bacteriol. | pmid:16385050 |
Shrake A et al. | Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions. | 2006 | Biopolymers | pmid:16273515 |
Delamarre SC and Batt CA | Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16362422 |
Vinson SB et al. | Nest liquid resources of several cavity nesting bees in the genus Centris and the identification of a preservative, levulinic acid. | 2006 | J. Chem. Ecol. | pmid:16902822 |
Amalaradjou MA et al. | Inactivation of escherichia coli O157:H7 in cattle drinking water by sodium caprylate. | 2006 | J. Food Prot. | pmid:16995532 |
Darnell ME and Taylor DR | Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products. | 2006 | Transfusion | pmid:17002634 |
Sanaka M et al. | Assessment of the gastric emptying velocity by the 13C-octanoate breath test: deconvolution versus a Wagner-Nelson analysis. | 2006 | J. Gastroenterol. | pmid:16933000 |
Bryant P et al. | The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate. | 2006 | Anal. Biochem. | pmid:16500612 |
Parkkinen J et al. | A modified caprylic acid method for manufacturing immunoglobulin G from human plasma with high yield and efficient virus clearance. | 2006 | Vox Sang. | pmid:16430667 |
Ayub ND et al. | Impaired polyhydroxybutyrate biosynthesis from glucose in Pseudomonas sp. 14-3 is due to a defective beta-ketothiolase gene. | 2006 | FEMS Microbiol. Lett. | pmid:17020558 |
Moechars D et al. | Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse. | 2006 | Gastroenterology | pmid:17030183 |
Che CM et al. | Ruthenium-catalyzed oxidation of alkenes, alkynes, and alcohols to organic acids with aqueous hydrogen peroxide. | 2006 | Chem Asian J | pmid:17441082 |
Redwan el-RM | Comparison between therapeutic antitoxin F(ab)2 fractionated with ammonium sulfate and caprylic acid. | 2006 | J Immunoassay Immunochem | pmid:16981645 |
Sanaka M et al. | Is the time for absorption and oxidation of 13c-octanoate really negligible in the gastric emptying breath test? | 2006 | Dig. Dis. Sci. | pmid:17120146 |
Jones PM et al. | Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16750167 |
Bouvet L et al. | Erythromycin promotes gastric emptying during acute pain in volunteers. | 2006 | Anesth. Analg. | pmid:16717329 |
Otero R et al. | Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia. | 2006 | Trans. R. Soc. Trop. Med. Hyg. | pmid:16698053 |
Vanden Heuvel JP et al. | Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. | 2006 | Toxicol. Sci. | pmid:16731579 |
Wilson TA et al. | Structured triglycerides containing caprylic (8:0) and oleic (18:1) fatty acids reduce blood cholesterol concentrations and aortic cholesterol accumulation in hamsters. | 2006 | Biochim. Biophys. Acta | pmid:16580874 |
Kachi M et al. | Effects of Helicobacter pylori eradication therapy on gastric emptying measured using the 13C-octanoic acid breath test and the acetaminophen method. | 2006 | J. Gastroenterol. Hepatol. | pmid:16704530 |
De Smet B et al. | Energy homeostasis and gastric emptying in ghrelin knockout mice. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16203827 |
Li YH et al. | [Effects of absorption enhancers on intestinal absorption of lumbrokinase]. | 2006 | Yao Xue Xue Bao | pmid:17184110 |
Conte E et al. | Regulation of polyhydroxyalkanoate synthases (phaC1 and phaC2) gene expression in Pseudomonas corrugata. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16607528 |
Tao F et al. | Competition and coadsorption of di-acids and carboxylic acid solvents on HOPG. | 2006 | J Phys Chem B | pmid:17004820 |
Hellmig S et al. | Gastric emptying time of fluids and solids in healthy subjects determined by 13C breath tests: influence of age, sex and body mass index. | 2006 | J. Gastroenterol. Hepatol. | pmid:17074022 |
Davaran S et al. | Adriamycin release from poly(lactide-coglycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization. | 2006 | Int J Nanomedicine | pmid:17722284 |
Guo W et al. | Modulation of adipocyte lipogenesis by octanoate: involvement of reactive oxygen species. | 2006 | Nutr Metab (Lond) | pmid:16872526 |
Kragh-Hansen U et al. | Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis. | 2006 | J. Mol. Biol. | pmid:16979183 |
Thorburn MS et al. | Attenuated gastric distress but no benefit to performance with adaptation to octanoate-rich esterified oils in well-trained male cyclists. | 2006 | J. Appl. Physiol. | pmid:16840580 |
Brill J et al. | Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami. | 2006 | J. Neurosci. | pmid:16793888 |
Gerhardt WW et al. | Functional lactide monomers: methodology and polymerization. | 2006 | Biomacromolecules | pmid:16768392 |
Aydin HM et al. | Attachment and growth of fibroblasts on poly(L-lactide/epsilon-caprolactone) scaffolds prepared in supercritical CO2 and modified by polyethylene imine grafting with ethylene diamine-plasma in a glow-discharge apparatus. | 2006 | Int J Artif Organs | pmid:17033995 |
Gasbarrini G et al. | Evaluation of thermal water in patients with functional dyspepsia and irritable bowel syndrome accompanying constipation. | 2006 | World J. Gastroenterol. | pmid:16688801 |
Hosoda H et al. | Biological, physiological, and pharmacological aspects of ghrelin. | 2006 | J. Pharmacol. Sci. | pmid:16612045 |
PuigmartÃ-Luis J et al. | Noncovalent control for bottom-up assembly of functional supramolecular wires. | 2006 | J. Am. Chem. Soc. | pmid:17002326 |
Elluru S et al. | Comparative study of the anti-inflammatory effect of two intravenous immunoglobulin preparations manufactured by different processes. | 2006 | Immunol. Lett. | pmid:16952403 |
Gil-Campos M et al. | Ghrelin: a hormone regulating food intake and energy homeostasis. | 2006 | Br. J. Nutr. | pmid:16923214 |
Jiang Y et al. | The soluble acyl-acyl carrier protein synthetase of Vibrio harveyi B392 is a member of the medium chain acyl-CoA synthetase family. | 2006 | Biochemistry | pmid:16906759 |
Matulka RA et al. | Safety evaluation of a medium- and long-chain triacylglycerol oil produced from medium-chain triacylglycerols and edible vegetable oil. | 2006 | Food Chem. Toxicol. | pmid:16753249 |
Hartmann R et al. | Tailor-made olefinic medium-chain-length poly[(R)-3-hydroxyalkanoates] by Pseudomonas putida GPo1: batch versus chemostat production. | 2006 | Biotechnol. Bioeng. | pmid:16255038 |
Wang J et al. | Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers. | 2006 | Peptides | pmid:16242213 |