octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Komura S and Kurahashi K | Biosynthesis of polymyxin E by a cell-free enzyme system. IV. Acylation of enzyme-bound L-2,4-diaminobutyric acid. | 1985 | J. Biochem. | pmid:3861608 |
| Bjorge SM and Baillie TA | Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3933498 |
| Haas R et al. | Salicylate-induced loose coupling: protonmotive force measurements. | 1985 | Biochem. Pharmacol. | pmid:3977963 |
| Taylor WM et al. | Effect of depolarizing concentrations of potassium on calcium uptake and metabolism in rat liver. | 1985 | FEBS Lett. | pmid:3979569 |
| Brandes R et al. | The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations. | 1985 | Biochim. Biophys. Acta | pmid:4027259 |
| Drewes LR and Leino RL | Neuron-specific mitochondrial degeneration induced by hyperammonemia and octanoic acidemia. | 1985 | Brain Res. | pmid:4027650 |
| Duran M et al. | Octanoic acidemia and octanoylcarnitine excretion with dicarboxylic aciduria due to defective oxidation of medium-chain fatty acids. | 1985 | J. Pediatr. | pmid:4032135 |
| Ferris CF et al. | Alcohol and fatty acid stimulation of neurotensin release from rat small intestine. | 1985 | Endocrinology | pmid:3971900 |
| Wolf HP and Engel DW | Decrease of fatty acid oxidation, ketogenesis and gluconeogenesis in isolated perfused rat liver by phenylalkyl oxirane carboxylate (B 807-27) due to inhibition of CPT I (EC 2.3.1.21). | 1985 | Eur. J. Biochem. | pmid:4038486 |
| Hütter JF et al. | Effect of fatty acid oxidation on efficiency of energy production in rat heart. | 1985 | Am. J. Physiol. | pmid:4051011 |
| Lutz WH et al. | Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides. | 1985 | Biochem Med | pmid:4052056 |
| Strieleman PJ et al. | Fatty acid activation of the reconstituted brown adipose tissue mitochondria uncoupling protein. | 1985 | J. Biol. Chem. | pmid:4055740 |
| Allen PC | Physiological responses of chicken gut tissue to infection with Eimeria acervulina. | 1984 Oct-Dec | Avian Dis. | pmid:6441557 |
| Pfadenhauer EH et al. | Identification of the metabolites of erythro-9-(2-hydroxy-3-nonyl)hypoxanthine from laboratory animals. | 1984 May-Jun | Drug Metab. Dispos. | pmid:6145553 |
| Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
| Otto DA | Relationship of the ATP/ADP ratio to the site of octanoate activation. | 1984 | J. Biol. Chem. | pmid:6715356 |
| Blumenthal SA | Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action. | 1984 | Biochem. J. | pmid:6430273 |
| Duran M et al. | The differential diagnosis of dicarboxylic aciduria. | 1984 | J. Inherit. Metab. Dis. | pmid:6434845 |
| Schudt C and Simon A | Effects of sodium 2-[5-(4-chlorophenyl)pentyl]-oxirane-2-carboxylate (POCA) on carbohydrate and fatty acid metabolism in liver and muscle. | 1984 | Biochem. Pharmacol. | pmid:6437406 |
| Allen PC and Danforth HD | The effects of Eimeria acervulina infection on the metabolism of chick duodenal tissue. | 1984 | Vet. Parasitol. | pmid:6538718 |
| Zieve L et al. | Brain methanethiol and ammonia concentrations in experimental hepatic coma and coma induced by injections of various combinations of these substances. | 1984 | J. Lab. Clin. Med. | pmid:6491466 |
| Riecken EO | [Structural and functional findings in experimental blind loop syndrome]. | 1984 | Nahrung | pmid:6493325 |
| Buxton DB et al. | Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart. | 1984 | Biochem. J. | pmid:6477487 |
| Kim CS et al. | L-carnitine: therapeutic strategy for metabolic encephalopathy. | 1984 | Brain Res. | pmid:6478235 |
| Wagenmakers AJ et al. | Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation. | 1984 | Biochem. J. | pmid:6517861 |
| Schönfeld P et al. | Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. | 1984 | Biomed. Biochim. Acta | pmid:6525184 |
| Pappas SC et al. | Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. | 1984 | Gastroenterology | pmid:6693016 |
| Kohlwein SD and Paltauf F | Uptake of fatty acids by the yeasts, Saccharomyces uvarum and Saccharomycopsis lipolytica. | 1984 | Biochim. Biophys. Acta | pmid:6696936 |
| Bell FP | Di(2-ethylhexyl)adipate (DEHA): effect on plasma lipids and hepatic cholesterolgenesis in the rat. | 1984 | Bull Environ Contam Toxicol | pmid:6697017 |
| Nauclér J et al. | Evaluation of kidney viability during hypothermic perfusion or cold storage. | 1984 | Eur Surg Res | pmid:6698069 |
| Martin-Sanz P et al. | Long-chain fatty acids and their acyl-CoA esters cause the translocation of phosphatidate phosphohydrolase from the cytosolic to the microsomal fraction of rat liver. | 1984 | FEBS Lett. | pmid:6090213 |
| Sundin U et al. | Thyroid-catecholamine interactions in isolated rat brown adipocytes. | 1984 | Metab. Clin. Exp. | pmid:6092828 |
| Baraldi M et al. | Toxins in hepatic encephalopathy: the role of the synergistic effect of ammonia, mercaptans and short chain fatty acids. | 1984 | Arch. Toxicol. Suppl. | pmid:6097201 |
| Claycomb WC et al. | Culture of the terminally differentiated ventricular cardiac muscle cell. Characterization of exogenous substrate oxidation and the adenylate cyclase system. | 1984 | FEBS Lett. | pmid:6201398 |
| White RH | The biosynthesis of n-[(2)H (7)] fatty acids byArthrobacter globiformis from [U-(2)H (15)] octanoic acid. | 1984 | Lipids | pmid:21344284 |
| Yu MW and Finlayson JS | Quantitative determination of the stabilizers octanoic acid and N-acetyl-DL-tryptophan in human albumin products. | 1984 | J Pharm Sci | pmid:6694090 |
| Chen V et al. | Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. | 1984 | Horm. Metab. Res. | pmid:6735347 |
| Soboll S et al. | Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. | 1984 | Biochem. J. | pmid:6743276 |
| Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
| Elliott JR et al. | The asymmetrical effects of some ionized n-octyl derivatives on the sodium current of the giant axon of Loligo forbesi. | 1984 | J. Physiol. (Lond.) | pmid:6747855 |
| Thayer WS | Inhibition of mitochondrial fatty acid oxidation in pentenoic acid-induced fatty liver. A possible model for Reye's syndrome. | 1984 | Biochem. Pharmacol. | pmid:6712730 |
| Habeeb AF and Francis RD | Preparation of human immunoglobulin by caprylic acid precipitation. | 1984 | Prep. Biochem. | pmid:6718324 |
| Reed WD et al. | A double-isotope method for the measurement of ketone-body turnover in the rat. Effect of L-alanine. | 1984 | Biochem. J. | pmid:6721850 |
| Soboll S et al. | Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6723661 |
| Aurousseau B et al. | [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. | 1984 | Reprod Nutr Dev | pmid:6729239 |
| Katoh K and Tsuda T | Effects of acetylcholine and short-chain fatty acids on acinar cells of the exocrine pancreas in sheep. | 1984 | J. Physiol. (Lond.) | pmid:6084059 |
| Kochel PJ et al. | Effects of noncarbohydrate substrates on protein synthesis in hearts from fed and fasted rats. | 1984 | J. Mol. Cell. Cardiol. | pmid:6374161 |
| Hampson RK et al. | Regulation of the glycine cleavage system in the isolated perfused rat liver. | 1984 | J. Biol. Chem. | pmid:6420402 |
| Scholz R et al. | Influence of fatty acids on energy metabolism. 1. Stimulation of oxygen consumption, ketogenesis and CO2 production following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6426957 |
| Salesse R and Garnier J | Adenylate cyclase and membrane fluidity. The repressor hypothesis. | 1984 | Mol. Cell. Biochem. | pmid:6323963 |