octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Perera J et al. | Neuroprotective effects of alpha lipoic Acid on haloperidol-induced oxidative stress in the rat brain. | 2011 | Cell Biosci | pmid:21711768 |
Etzerodt T et al. | Selective acylation enhances membrane charge sensitivity of the antimicrobial peptide mastoparan-x. | 2011 | Biophys. J. | pmid:21244836 |
Best L et al. | A dual action of saturated fatty acids on electrical activity in rat pancreatic β-cells. Role of volume-regulated anion channel and KATP channel currents. | 2011 | J. Physiol. (Lond.) | pmid:21242256 |
Novaretti MC and Dinardo CL | Immunoglobulin: production, mechanisms of action and formulations. | 2011 | Rev Bras Hematol Hemoter | pmid:23049343 |
Kaiya H et al. | Ghrelin Receptor in Two Species of Anuran Amphibian, Bullfrog (Rana catesbeiana), and Japanese Tree Frog (Hyla japonica). | 2011 | Front Endocrinol (Lausanne) | pmid:22654801 |
Choi MH et al. | Metabolic relationship between polyhydroxyalkanoic acid and rhamnolipid synthesis in Pseudomonas aeruginosa: comparative ¹³C NMR analysis of the products in wild-type and mutants. | 2011 | J. Biotechnol. | pmid:21029757 |
Huang L et al. | Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for breast cancer therapy. | 2011 | Integr Biol (Camb) | pmid:21938302 |
Kojima M and Kangawa K | The discovery of ghrelin: with a little luck and great passion. Preface. | 2011 | Peptides | pmid:22027335 |
Vavricka CJ et al. | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. | 2011 | PLoS Pathog. | pmid:22028647 |
Mizrahi M et al. | Dumping syndrome following nissen fundoplication in an adult patient diagnosed by continuous online 13C/12C monitoring of ¹³C-Octanoic acid breath test "a case report". | 2011 | BMC Gastroenterol | pmid:21929798 |
de Moura AF et al. | Solvation of sodium octanoate micelles in concentrated urea solution studied by means of molecular dynamics simulations. | 2011 | J Phys Chem B | pmid:22026457 |
Kumar S | Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. | 2011 | Bioinformation | pmid:22355237 |
Calzadilla P et al. | N-acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes. | 2011 | Int J Mol Sci | pmid:22072928 |
Cheng YY et al. | A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. | 2011 | Int J Mol Sci | pmid:22072918 |
Peng Q et al. | A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. | 2011 | Microb. Cell Fact. | pmid:22067554 |
Yu WL et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. | 2011 | Microb. Cell Fact. | pmid:22047615 |
Bondia-Pons I et al. | Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. | 2011 | Nutr J | pmid:22011443 |
Feng L et al. | Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo. | 2011 | Int J Nanomedicine | pmid:22072889 |
Valipe SR et al. | In vitro antimicrobial properties of caprylic acid, monocaprylin, and sodium caprylate against Dermatophilus congolensis. | 2011 | Am. J. Vet. Res. | pmid:21355735 |
Fieker A et al. | Enzyme replacement therapy for pancreatic insufficiency: present and future. | 2011 | Clin Exp Gastroenterol | pmid:21753892 |
Lan DM et al. | A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. | 2011 | Int J Mol Sci | pmid:21747717 |
de Azevedo Mde B et al. | New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles. | 2011 | Int J Nanomedicine | pmid:21720512 |
Satoh Y et al. | Isolation of a thermotolerant bacterium producing medium-chain-length polyhydroxyalkanoate. | 2011 | J. Appl. Microbiol. | pmid:21714837 |
Duarte JM et al. | Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T. | 2011 | Front Neuroenergetics | pmid:21713114 |
Stavarachi M et al. | Spinal muscular atrophy disease: a literature review for therapeutic strategies. | 2010 Jan-Mar | J Med Life | pmid:20302191 |
Fernández GP et al. | Neutralization of Bothrops mattogrossensis snake venom from Bolivia: experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation. | 2010 Feb-Mar | Toxicon | pmid:19647761 |
Franta Z et al. | Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. | 2010 | Parasit Vectors | pmid:21156061 |
Cheung WW and Mak RH | Ghrelin in chronic kidney disease. | 2010 | Int J Pept | pmid:20721357 |
Sallam HS and Chen JD | The prokinetic face of ghrelin. | 2010 | Int J Pept | pmid:20721347 |
Koizumi M et al. | Reconstruction-dependent recovery from anorexia and time-related recovery of regulatory ghrelin system in gastrectomized rats. | 2010 | Int J Pept | pmid:20721337 |
Gómez-Pastor R et al. | Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass. | 2010 | Microb. Cell Fact. | pmid:20152017 |
Pulkkinen L et al. | Ghrelin in diabetes and metabolic syndrome. | 2010 | Int J Pept | pmid:20700400 |
Hammar O et al. | Impaired gastric emptying in primary Sjogren's syndrome. | 2010 | J. Rheumatol. | pmid:20810502 |
Satou M et al. | Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium. | 2010 | Endocrinology | pmid:20685872 |
Akpa MM et al. | Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. | 2010 | Lipids | pmid:20811782 |
Lengi AJ and Corl BA | Factors influencing the differentiation of bovine preadipocytes in vitro. | 2010 | J. Anim. Sci. | pmid:20154153 |
Fain JN et al. | The inflammatory response seen when human omental adipose tissue explants are incubated in primary culture is not dependent upon albumin and is primarily in the nonfat cells. | 2010 | J Inflamm (Lond) | pmid:20145729 |
Kojima M and Kangawa K | Ghrelin: from gene to physiological function. | 2010 | Results Probl Cell Differ | pmid:19859676 |
Beglinger S et al. | Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion. | 2010 | J. Clin. Endocrinol. Metab. | pmid:19837920 |
Kovalchuk NM and Vollhardt D | Auto-oscillation of surface tension: effect of pH on fatty acid systems. | 2010 | Langmuir | pmid:20726531 |
Okumu FO et al. | Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. | 2010 | PLoS ONE | pmid:20126628 |
Murzyn A et al. | Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. | 2010 | PLoS ONE | pmid:20706577 |
Patel SK et al. | Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. | 2010 | Biomaterials | pmid:19796808 |
Mills JK et al. | The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. | 2010 | J. Dairy Sci. | pmid:20723699 |
Wylie-van Eerd BJ et al. | Ligand-functionalised copper(II) hydroxide for quantum dot photoluminescence quenching. | 2010 | J Colloid Interface Sci | pmid:20350726 |
Yuan JS et al. | Effect of surfactant concentration on transdermal lidocaine delivery with linker microemulsions. | 2010 | Int J Pharm | pmid:20363304 |
Blanco E et al. | Effect of alkyl chain asymmetry on catanionic mixtures of hydrogenated and fluorinated surfactants. | 2010 | J Colloid Interface Sci | pmid:19853859 |
Ma J et al. | Effects of cefaclor on gastric emptying and cholecystokinin release in healthy humans. | 2010 | Regul. Pept. | pmid:19914303 |
Magliano P et al. | Repercussion of a deficiency in mitochondrial ß-oxidation on the carbon flux of short-chain fatty acids to the peroxisomal ß-oxidation cycle in Aspergillus nidulans. | 2010 | Biochim. Biophys. Acta | pmid:20736083 |
Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |