octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Snake Bites D012909 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chickenpox D002644 1 associated lipids
Essential Tremor D020329 2 associated lipids
Gastroparesis D018589 2 associated lipids
Prion Diseases D017096 2 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Gallstones D042882 3 associated lipids
Malocclusion D008310 3 associated lipids
Giardiasis D005873 3 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Guan Z Identification and localization of the fatty acid modification in ghrelin by electron capture dissociation. 2002 J. Am. Soc. Mass Spectrom. pmid:12484464
Laurendeau G and Roy CC Effect of cholestasis and biliary diversion on the absorption of Na octanoate in the rat. 1976 Experientia pmid:1248600
Seddik SS et al. Improved purification and yield of the Egyptian snake Cerastes cerastes antitoxin by the use of caprylic acid. 2002 J Nat Toxins pmid:12503875
Sugihara A et al. Purification and characterization of a novel cholesterol esterase from Pseudomonas aeruginosa, with its application to cleaning lipid-stained contact lenses. 2002 Biosci. Biotechnol. Biochem. pmid:12506971
Wang H and Xie X [Effect of varied sample treatment procedures on detection of hepatitis B virus DNA]. 1998 Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi pmid:12515203
Rodriguez M et al. Plasma fatty acids and [13C]linoleic acid metabolism in preterm infants fed a formula with medium-chain triglycerides. 2003 J. Lipid Res. pmid:12518021
Chen CP et al. Infrared spectrometry based 13C-octanoic acid breath test in measuring human solid gastric emptying. 2003 J. Gastroenterol. Hepatol. pmid:12519222
Lamabadusuriya SP et al. Influence of mixtures of taurocholate, fatty acids, and monolein on the toxic effects of deoxycholate in rat jejunum in vivo. 1975 Gastroenterology pmid:125213
Beaumont NJ et al. Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase. 2003 J. Biol. Chem. pmid:12531885
St-Onge MP et al. Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. 2003 Int. J. Obes. Relat. Metab. Disord. pmid:12532160
Nowak-Thompson B et al. 2,5-dialkylresorcinol biosynthesis in Pseudomonas aurantiaca: novel head-to-head condensation of two fatty acid-derived precursors. 2003 J. Bacteriol. pmid:12533461
Campbell JW et al. A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic beta-oxidation pathway. 2003 Mol. Microbiol. pmid:12535077
Sutton DG et al. Validation of the 13C-octanoic acid breath test for measurement of equine gastric emptying rate of solids using radioscintigraphy. 2003 Equine Vet. J. pmid:12553459
Heurtault B et al. The influence of lipid nanocapsule composition on their size distribution. 2003 Eur J Pharm Sci pmid:12554073
Small RW An X-ray diffraction study of partially ordered electron density in clathrates of Dianin's compound that include simple carboxylic acids. 2003 Acta Crystallogr., B pmid:12554979
Maes BD et al. Gastric emptying in renal failure patients using the 13C-octanoic acid breath test: facts and artifacts. 2002 Nov-Dec Perit Dial Int pmid:12556082
Gimeno RE et al. Characterization of a heart-specific fatty acid transport protein. 2003 J. Biol. Chem. pmid:12556534
Duque-Beltrán S et al. Detection of Giardia duodenalis antigen in human fecal eluates by enzyme-linked immunosorbent assay using polyclonal antibodies. 2002 Mem. Inst. Oswaldo Cruz pmid:12563485
Howard PL Blood bank reagents: some problems related to preservatives and dyes. 1976 Mar-Apr Transfusion pmid:1258119
Wyse CA et al. A comparison of the rate of recovery of 13CO2 in exhaled breath with 2H in body water following ingestion of [2H/13C]octanoic acid in a dog. 2003 Res. Vet. Sci. pmid:12589736