octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chickenpox D002644 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Gastroparesis D018589 2 associated lipids
Prion Diseases D017096 2 associated lipids
Essential Tremor D020329 2 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Gallstones D042882 3 associated lipids
Malocclusion D008310 3 associated lipids
Giardiasis D005873 3 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
BROWN GW et al. The oxidative metabolic pattern of mouse hepatoma C954 as studied with C14-labeled acetates, propionate, octanoate, and glucose. 1956 Cancer Res. pmid:13343123
REES ED and KLINE DL Metabolism of octanoate by fatty liver slices. 1957 Am. J. Physiol. pmid:13470069
LOSSOW WJ and CHAIKOFF IL Secretion of intravenously administered tripalmitin-1-C14 and octanoate-1-C14 into milk by the lactating rat. 1958 J. Biol. Chem. pmid:13502382
Prip-Buus C et al. Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells. 1992 Eur. J. Biochem. pmid:1356769
Berger M et al. Glucose metabolism in perfused skeletal muscle. Effects of starvation, diabetes, fatty acids, acetoacetate, insulin and exercise on glucose uptake and disposition. 1976 Biochem. J. pmid:136249
Kristev A et al. Effects of the medium chain octanoic fatty acid on the contractile activity of vascular smooth muscle tissues. 1992 Folia Med (Plovdiv) pmid:1364081
Favre-Bulle O et al. Bioconversion of n-octane to octanoic acid by a recombinant Escherichia coli cultured in a two-liquid phase bioreactor. 1991 Biotechnology (N.Y.) pmid:1367010
DIANZANI MU and MARINARI U The octanoate oxidation by mitochondria from faty livers. 1961 Biochim. Biophys. Acta pmid:13722612
Kim CS et al. Octanoic acid produces accumulation of monoamine acidic metabolites in the brain: interaction with organic anion transport at the choroid plexus. 1992 J. Neurochem. pmid:1372345
Ohkubo Y et al. Presence and properties of acyl coenzyme A synthetase for medium-chain fatty acids in rat intestinal mucosa. 1992 Digestion pmid:1386328
BROADBENT JL Importance of calcium in the actions of some drugs that stimulate the isolated hypodynamic frog heart. 1962 Br J Pharmacol Chemother pmid:13873208
GLENN JL et al. Rare-earth fatty liver. I. Octanoate oxidation and energy production. 1962 Biochim. Biophys. Acta pmid:13899206
GEHRIG RF and KNIGHT SG Fatty acid oxidation by spores of Penicillium roqueforti. 1963 Appl Microbiol pmid:13947000
Noctor TA et al. Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. 1992 J. Chromatogr. pmid:1400761
Scholte HR et al. Assessment of deficiencies of fatty acyl-CoA dehydrogenases in fibroblasts, muscle and liver. 1992 J. Inherit. Metab. Dis. pmid:1405467
BROADBENT JL THE INTERACTION OF SOME STIMULANT AND DEPRESSANT DRUGS ON THE FROG HEART. 1963 Br J Pharmacol Chemother pmid:14066153
ADAMS JN et al. EFFECTS OF SODIUM CAPRYLATE ON CANDIDA ALBICANS. I. INFLUENCE OF CONCENTRATION ON ULTRASTRUCTURE. 1963 J. Bacteriol. pmid:14066435
PAYNE WJ and BANNISTER ER EFFECTS OF SODIUM CAPRYLATE ON CANDIDA ALBICANS. II. INFLUENCE OF VARIOUS CONCENTRATIONS ON BIOCHEMICAL CHANGES. 1963 J. Bacteriol. pmid:14066436
SMITH JA and DELUCA HF STRUCTURAL CHANGES IN ISOLATED LIVER MITOCHONDRIA OF RATS DURING ESSENTIAL FATTY ACID DEFICIENCY. 1964 J. Cell Biol. pmid:14154491
SCHWABE AD et al. OCTANOIC ACID ABSORPTION AND OXIDATION IN HUMANS. 1964 J Appl Physiol pmid:14155309