octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatorenal Syndrome D006530 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Flatulence D005414 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Chickenpox D002644 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chylothorax D002916 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Prion Diseases D017096 2 associated lipids
Essential Tremor D020329 2 associated lipids
Gastroparesis D018589 2 associated lipids
Gallstones D042882 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Malocclusion D008310 3 associated lipids
Giardiasis D005873 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Schistosomiasis D012552 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Carrington MJ et al. Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. 1981 Biochem. Soc. Trans. pmid:7215663
Parameswaran M and Arinze IJ Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria. 1981 Biochim. Biophys. Acta pmid:7225415
Chace KV and Odessey R The utilization by rabbit aorta of carbohydrates, fatty acids, ketone bodies, and amino acids as substrates for energy production. 1981 Circ. Res. pmid:7226445
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Rosario P and Medina JM Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. 1981 Rev. Esp. Fisiol. pmid:7244329
Sumbilla CM et al. Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. 1981 Biochim. Biophys. Acta pmid:7272339
Kaler LW and Neaves WB The steroidogenic capacity of the aging rat testis. 1981 J Gerontol pmid:7252069
Dimenna GP and Emery RS Palmitate and octanoate metabolism in bovine mammary tissue. 1981 J. Dairy Sci. pmid:7264015
Wells JW et al. The biosynthesis of progesterone by fowl granulosa cells in vitro from 14C-labelled substrates. 1981 J. Steroid Biochem. pmid:7265968
Trauner DA and Adams H Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. 1981 Pediatr. Res. pmid:7267183
Ferré P et al. Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. 1981 Biochem. J. pmid:7340842
Burns AH and Reddy WJ Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. 1981 Res. Commun. Chem. Pathol. Pharmacol. pmid:6267674
Henze K et al. The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. 1981 Biochim. Biophys. Acta pmid:6118180
Müller MJ et al. Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. 1981 Biochim. Biophys. Acta pmid:6275888
Pegg DE et al. Metabolism of normal and ischemically injured rabbit kidneys during perfusion for 48 hours at 10 C. 1981 Transplantation pmid:7330963
Morgenthaler JJ et al. Fatty acid patterns during plasma fractionation. 1980 Vox Sang. pmid:7415075
Schenk J et al. Treatment of choledocholithiasis using the transpapillary perfusion technique. 1980 Endoscopy pmid:7428727
Krisans SK et al. Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. 1980 J. Biol. Chem. pmid:7430088
Waymack PP et al. Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. 1980 J. Biol. Chem. pmid:7430101
Barth CA et al. Morphology and metabolism of adult rat hepatocytes in primary culture. 1980 Hoppe-Seyler's Z. Physiol. Chem. pmid:6997170