| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
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|---|---|---|---|---|
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| Metcalf JH et al. | Water administration of the medium-chain fatty acid caprylic acid produced variable efficacy against enteric Campylobacter colonization in broilers. | 2011 | Poult. Sci. | pmid:21248350 |
| Kollanoor-Johny A et al. | Caprylic acid reduces Salmonella Enteritidis populations in various segments of digestive tract and internal organs of 3- and 6-week-old broiler chickens, therapeutically. | 2012 | Poult. Sci. | pmid:22700516 |
| Solis de los Santos F et al. | The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. | 2009 | Poult. Sci. | pmid:19096058 |
| Tien ES et al. | Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha). | 2006 | PPAR Res | pmid:17259669 |
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| Bennett MJ et al. | Prenatal diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency. | 1987 | Prenat. Diagn. | pmid:3575262 |
| Habeeb AF and Francis RD | Preparation of human immunoglobulin by caprylic acid precipitation. | 1984 | Prep. Biochem. | pmid:6718324 |
| Omura T | Recollection of the early years of the research on cytochrome P450. | 2011 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:22156409 |
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| Jenkins DL and Griffith OW | Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3455765 |
| Gutierrez JA et al. | Ghrelin octanoylation mediated by an orphan lipid transferase. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18443287 |
| Merritt ME et al. | Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18056642 |
| Pi-Sunyer FX | Effect of long- and medium-chain fatty acids on insulin secretion from pieces of rat pancreas. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1144459 |
| Paquet RJ et al. | Effects of thiamine deficiency and octanoate administration, in vivo, on gluconeogenesis in rat kidney slices and on amino acid profile in rat liver. | 1972 | Proc. Soc. Exp. Biol. Med. | pmid:5039394 |
| Morrow RJ et al. | Functional utilization of palmitate, octanoate, and glucose by the isolated rat heart. | 1973 | Proc. Soc. Exp. Biol. Med. | pmid:4683244 |
| Maragoudakis ME et al. | Metabolism of octanoate and its effect on glucose and palmitate utilization by isolated fat cells. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:236573 |
| McDonough KH and Spitzer JJ | Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. | 1983 | Proc. Soc. Exp. Biol. Med. | pmid:6412237 |