octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Starvation D013217 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Trauner DA and Huttenlocher PR Short chain fatty acid-induced central hyperventilation in rabbits. 1978 Neurology pmid:567765
Demol P and Sarles H Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. 1978 J. Physiol. (Lond.) pmid:633115
Hansford RG Lipid oxidation by heart mitochondria from young adult and senescent rats. 1978 Biochem. J. pmid:637843
Meisner H and Neet K Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. 1978 Mol. Pharmacol. pmid:642932
Mannaerts GP et al. Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. 1978 Biochim. Biophys. Acta pmid:656451
Scholz R et al. The effect of fatty acids on the regulation of pyruvate dehydrogenase in perfused rat liver. 1978 Eur. J. Biochem. pmid:658055
Rabinowitz JL et al. Sources of serum [14C]-octanoate in cirrhosis of the liver and hepatic encephalopathy. 1978 J. Lab. Clin. Med. pmid:621424
Kinnula VL and Hassinen I Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart. 1978 Acta Physiol. Scand. pmid:626089
Burns AH and Reddy WJ Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. 1978 Am. J. Physiol. pmid:727249
Fildes FJ and Oliver JE Interaction of cortisol-21-palmitate with liposomes examined by differential scanning calorimetry. 1978 J. Pharm. Pharmacol. pmid:26761
Sheikh MI et al. On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. 1978 Arch. Int. Physiol. Biochim. pmid:87158
Rabinowitz JL et al. The effects of intravenous sodium octanoate on the rhesus monkey. 1978 Am. J. Gastroenterol. pmid:96693
Trimble ME et al. Fatty acid transport and metabolism in the isolated perfused rat kidney. 1977 Oct 23-26 Curr Probl Clin Biochem pmid:616371
Lemieux G et al. Relationship between the renal metabolism of glutamine, fatty acids and ketone bodies. 1977 Oct 23-26 Curr Probl Clin Biochem pmid:616372
Hossaini AA et al. Experimental induction of caprylate-dependent albumin antibodies. 1977 Jan-Feb Transfusion pmid:841674
Ruderman NB et al. Effect of starvation on muscle glucose metabolism: studies with the isolated perfused rat hindquarter. 1977 Fed. Proc. pmid:838085
Rabinowitz JL et al. A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. 1977 Clin. Chem. pmid:923071
Pérez-Diaz J et al. Preparation and metabolic characterization of isolated rat lung cells. 1977 Biochimie pmid:195638
Elliott KR and Pogson CI Preparation and characterization of isolated parenchymal cells from guinea pig liver. 1977 Mol. Cell. Biochem. pmid:196181
Fellenberg AJ and Pollard AC A rapid and sensitive gas-liquid chromatographic procedure for the micro determination of sodium valproate (sodium di-N-propylacetate) in plasma or serum. 1977 Clin. Chim. Acta pmid:338203