octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Asthenia D001247 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Fistula D001658 13 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Chest Pain D002637 4 associated lipids
Chickenpox D002644 1 associated lipids
Chronic Disease D002908 7 associated lipids
Chylothorax D002916 1 associated lipids
Coccidiosis D003048 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Crohn Disease D003424 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Parameswaran M and Arinze IJ Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria. 1981 Biochim. Biophys. Acta pmid:7225415
Chace KV and Odessey R The utilization by rabbit aorta of carbohydrates, fatty acids, ketone bodies, and amino acids as substrates for energy production. 1981 Circ. Res. pmid:7226445
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Rosario P and Medina JM Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. 1981 Rev. Esp. Fisiol. pmid:7244329
Sumbilla CM et al. Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. 1981 Biochim. Biophys. Acta pmid:7272339
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Balint JA et al. Desaturation of endogenous and exogenous palmitate in lung tissue in vitro. 1981 Lipids pmid:7300595
Kragh-Hansen U Effects of aliphatic fatty acids on the binding of Phenol Red to human serum albumin. 1981 Biochem. J. pmid:7316975
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Ferré P et al. Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. 1981 Biochem. J. pmid:7340842
Burns AH and Reddy WJ Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. 1981 Res. Commun. Chem. Pathol. Pharmacol. pmid:6267674
Henze K et al. The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. 1981 Biochim. Biophys. Acta pmid:6118180
Müller MJ et al. Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. 1981 Biochim. Biophys. Acta pmid:6275888
Pegg DE et al. Metabolism of normal and ischemically injured rabbit kidneys during perfusion for 48 hours at 10 C. 1981 Transplantation pmid:7330963
Buchowicz I et al. Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. 1981 Arch. Immunol. Ther. Exp. (Warsz.) pmid:6812541
Caffier G et al. The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. 1980 Pflugers Arch. pmid:6966791
Kössler F et al. Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. 1980 Chem. Biol. Interact. pmid:6967777
Caffier G and Küchler G [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. 1980 Acta Biol. Med. Ger. pmid:6969509
Chan SC Monitoring serum valproic acid by gas chromatography with electron-capture detection. 1980 Clin. Chem. pmid:6774836
Bijlsma R Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. 1980 Biochem. Genet. pmid:6781470