octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Asthenia D001247 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Fistula D001658 13 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Chest Pain D002637 4 associated lipids
Chickenpox D002644 1 associated lipids
Chronic Disease D002908 7 associated lipids
Chylothorax D002916 1 associated lipids
Coccidiosis D003048 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Crohn Disease D003424 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Rosario P and Medina JM Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. 1980 Rev. Esp. Fisiol. pmid:7221165
Morgenthaler JJ et al. Fatty acid patterns during plasma fractionation. 1980 Vox Sang. pmid:7415075
Schenk J et al. Treatment of choledocholithiasis using the transpapillary perfusion technique. 1980 Endoscopy pmid:7428727
Krisans SK et al. Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. 1980 J. Biol. Chem. pmid:7430088
Waymack PP et al. Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. 1980 J. Biol. Chem. pmid:7430101
Sugano T et al. Intracellular redox state and stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused rat liver. 1980 J. Biochem. pmid:7358625
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Kössler F et al. [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. V. Relations between twitch, tetanus and contracture]. 1980 Acta Biol. Med. Ger. pmid:7445906
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Bartels PD and Sestoft L Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. 1980 Biochim. Biophys. Acta pmid:7448206
Zammit VA The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. 1980 Biochem. J. pmid:7470052
Petcu LG and Plaut GW NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. 1980 Biochem. J. pmid:7470071
Trauner DA Regional cerebral Na+K+ ATPase activity following octanoate administration. 1980 Pediatr. Res. pmid:6250122
Barth CA et al. Morphology and metabolism of adult rat hepatocytes in primary culture. 1980 Hoppe-Seyler's Z. Physiol. Chem. pmid:6997170
Caffier G et al. The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. 1980 Pflugers Arch. pmid:6966791
Kössler F et al. Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. 1980 Chem. Biol. Interact. pmid:6967777
Sánchez-Serrano D et al. Enhancement of ouabain arrhythmias by fatty acids. 1980 J. Cardiovasc. Pharmacol. pmid:6156330
White RH Stable isotope studies on the biosynthesis of lipoic acid in Escherichia coli. 1980 Biochemistry pmid:6766313
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Dhopeshwarkar GA and Subramanian C Lipogenesis in the developing brain: utilization of radioactive leucine, isoleucine, octanoic acid and beta-hydroxybutyric acid. 1979 Lipids pmid:423709