octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Asthenia D001247 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Fistula D001658 13 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Chest Pain D002637 4 associated lipids
Chickenpox D002644 1 associated lipids
Chronic Disease D002908 7 associated lipids
Chylothorax D002916 1 associated lipids
Coccidiosis D003048 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Crohn Disease D003424 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Bartels PD and Sestoft L Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. 1980 Biochim. Biophys. Acta pmid:7448206
Zammit VA The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. 1980 Biochem. J. pmid:7470052
Petcu LG and Plaut GW NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. 1980 Biochem. J. pmid:7470071
Yanai S et al. Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma. 1995 Pharm. Res. pmid:7479548
Onkenhout W et al. Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. 1995 Clin. Chem. pmid:7586519
Duan LP et al. Influence of cisapride on gastric emptying of solids and liquids monitored by 13C breath tests. 1995 Dig. Dis. Sci. pmid:7587790
Nagatsugi F et al. 18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution. 1995 Chem. Pharm. Bull. pmid:7600614
Grekin RJ et al. Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. 1995 Hypertension pmid:7607723
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
Sibille B et al. Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes. 1995 Eur. J. Biochem. pmid:7635161
Martinelle M and Hult K Kinetics of acyl transfer reactions in organic media catalysed by Candida antarctica lipase B. 1995 Biochim. Biophys. Acta pmid:7669809
Svendsen L et al. Development and comparison of purification strategies for chicken antibodies from egg yolk. 1995 Lab. Anim. Sci. pmid:7752622
Pfaffenbach B et al. [Non-invasive 13C octanoic acid breath test for measuring stomach emptying of a solid test meal--correlation with scintigraphy in diabetic patients and reproducibility in healthy probands]. 1995 Z Gastroenterol pmid:7754644
Pettirossi O et al. Prolongation of rat heart allograft survival by a synthetic progestogen (melengestrol acetate) and ara-cytidine acylates. 1976 Transplantation pmid:775705
Fryer LG et al. The long-term regulation of skeletal muscle pyruvate dehydrogenase kinase by dietary lipid is dependent on fatty acid composition. 1995 Eur. J. Biochem. pmid:7758471
Berne C The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies. 1975 Biochem. J. pmid:776173
Maes BD et al. Influence of octreotide on the gastric emptying of solids and liquids in normal healthy subjects. 1995 Aliment. Pharmacol. Ther. pmid:7766738
Garratty G Problems in pre-transfusion tests related to drugs and chemicals. 1976 Am J Med Technol pmid:779471
McLaren RD et al. The use of caprylic acid for the extraction of the immunoglobulin fraction from egg yolk of chickens immunised with ovine alpha-lactalbumin. 1994 J. Immunol. Methods pmid:7822824
Redondo O et al. Comparative kinetic study of lipases A and B from Candida rugosa in the hydrolysis of lipid p-nitrophenyl esters in mixed micelles with Triton X-100. 1995 Biochim. Biophys. Acta pmid:7827103