octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Gallstones D042882 3 associated lipids
Essential Tremor D020329 2 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Endotoxemia D019446 27 associated lipids
Gastroparesis D018589 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Prion Diseases D017096 2 associated lipids
Liver Failure D017093 5 associated lipids
Critical Illness D016638 13 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Urinary Incontinence D014549 4 associated lipids
Stomach Diseases D013272 7 associated lipids
Starvation D013217 47 associated lipids
Snake Bites D012909 1 associated lipids
Seizures D012640 87 associated lipids
Schistosomiasis D012552 4 associated lipids
Reye Syndrome D012202 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Nauclér J et al. Evaluation of kidney viability during hypothermic perfusion or cold storage. 1984 Eur Surg Res pmid:6698069
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Pösö AR and Mortimore GE Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6589593
Chen V et al. Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. 1984 Horm. Metab. Res. pmid:6735347
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Rhead WJ et al. Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. 1983 Science pmid:6857268
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Shapiro IM et al. Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcification. 1983 Biosci. Rep. pmid:6871381
Shimizu H [Comparative studies on perfused adult and fetal guinea pig liver metabolism before and after anoxia loadings, with special reference to intracellular redox state]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6875338
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Bünger R et al. Energy utilization and pyruvate as determinants of pyruvate dehydrogenase in norepinephrine-stimulated heart. 1983 Pflugers Arch. pmid:6878010
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Zieve L et al. Toxicity of a fatty acid and ammonia: interactions with hypoglycemia and Krebs cycle inhibition. 1983 J. Lab. Clin. Med. pmid:6343534
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
McDonough KH and Spitzer JJ Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. 1983 Proc. Soc. Exp. Biol. Med. pmid:6412237
Nagi MN et al. Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase. 1983 Arch. Biochem. Biophys. pmid:6416174
Nomura T et al. Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. 1983 Biochim. Biophys. Acta pmid:6317044