octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Gallstones D042882 3 associated lipids
Essential Tremor D020329 2 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Endotoxemia D019446 27 associated lipids
Gastroparesis D018589 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Prion Diseases D017096 2 associated lipids
Liver Failure D017093 5 associated lipids
Critical Illness D016638 13 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Urinary Incontinence D014549 4 associated lipids
Stomach Diseases D013272 7 associated lipids
Starvation D013217 47 associated lipids
Snake Bites D012909 1 associated lipids
Seizures D012640 87 associated lipids
Schistosomiasis D012552 4 associated lipids
Reye Syndrome D012202 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Bartels PD and Sestoft L Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. 1980 Biochim. Biophys. Acta pmid:7448206
Zammit VA The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. 1980 Biochem. J. pmid:7470052
Petcu LG and Plaut GW NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. 1980 Biochem. J. pmid:7470071
Yanai S et al. Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma. 1995 Pharm. Res. pmid:7479548
Onkenhout W et al. Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. 1995 Clin. Chem. pmid:7586519
Duan LP et al. Influence of cisapride on gastric emptying of solids and liquids monitored by 13C breath tests. 1995 Dig. Dis. Sci. pmid:7587790
Nagatsugi F et al. 18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution. 1995 Chem. Pharm. Bull. pmid:7600614
Grekin RJ et al. Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. 1995 Hypertension pmid:7607723
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
Sibille B et al. Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes. 1995 Eur. J. Biochem. pmid:7635161
Martinelle M and Hult K Kinetics of acyl transfer reactions in organic media catalysed by Candida antarctica lipase B. 1995 Biochim. Biophys. Acta pmid:7669809
Svendsen L et al. Development and comparison of purification strategies for chicken antibodies from egg yolk. 1995 Lab. Anim. Sci. pmid:7752622
Pfaffenbach B et al. [Non-invasive 13C octanoic acid breath test for measuring stomach emptying of a solid test meal--correlation with scintigraphy in diabetic patients and reproducibility in healthy probands]. 1995 Z Gastroenterol pmid:7754644
Pettirossi O et al. Prolongation of rat heart allograft survival by a synthetic progestogen (melengestrol acetate) and ara-cytidine acylates. 1976 Transplantation pmid:775705
Fryer LG et al. The long-term regulation of skeletal muscle pyruvate dehydrogenase kinase by dietary lipid is dependent on fatty acid composition. 1995 Eur. J. Biochem. pmid:7758471
Berne C The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies. 1975 Biochem. J. pmid:776173
Maes BD et al. Influence of octreotide on the gastric emptying of solids and liquids in normal healthy subjects. 1995 Aliment. Pharmacol. Ther. pmid:7766738
Garratty G Problems in pre-transfusion tests related to drugs and chemicals. 1976 Am J Med Technol pmid:779471
McLaren RD et al. The use of caprylic acid for the extraction of the immunoglobulin fraction from egg yolk of chickens immunised with ovine alpha-lactalbumin. 1994 J. Immunol. Methods pmid:7822824
Redondo O et al. Comparative kinetic study of lipases A and B from Candida rugosa in the hydrolysis of lipid p-nitrophenyl esters in mixed micelles with Triton X-100. 1995 Biochim. Biophys. Acta pmid:7827103