octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Davaran S et al. Adriamycin release from poly(lactide-coglycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization. 2006 Int J Nanomedicine pmid:17722284
Li D et al. In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Y-shaped copolymers. 2012 Int J Nanomedicine pmid:22701317
Meyer H et al. Lipidic nanocapsule drug delivery: neuronal protection for cochlear implant optimization. 2012 Int J Nanomedicine pmid:22654517
Shi S et al. Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro. 2012 Int J Nanomedicine pmid:22619525
Akbarzadeh A et al. Preparation and in vitro evaluation of doxorubicin-loaded Fe₃O₄ magnetic nanoparticles modified with biocompatible copolymers. 2012 Int J Nanomedicine pmid:22334781
Feng L et al. Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo. 2011 Int J Nanomedicine pmid:22072889
de Azevedo Mde B et al. New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles. 2011 Int J Nanomedicine pmid:21720512
Foschi D et al. Treatment of morbid obesity by intraparietogastric administration of botulinum toxin: a randomized, double-blind, controlled study. 2007 Int J Obes (Lond) pmid:17006442
Veldhuis JD and Bowers CY Integrating GHS into the Ghrelin System. 2010 Int J Pept pmid:20798846
Richards MP and McMurtry JP The avian proghrelin system. 2010 Int J Pept pmid:20798876
Sakata I and Sakai T Ghrelin cells in the gastrointestinal tract. 2010 Int J Pept pmid:20798855
Fetissov SO et al. Update on ghrelin. 2010 Int J Pept pmid:20798849
Laviano A et al. Chronic renal failure, cachexia, and ghrelin. 2010 Int J Pept pmid:20798758
Cheung WW and Mak RH Ghrelin in chronic kidney disease. 2010 Int J Pept pmid:20721357
Sallam HS and Chen JD The prokinetic face of ghrelin. 2010 Int J Pept pmid:20721347
Koizumi M et al. Reconstruction-dependent recovery from anorexia and time-related recovery of regulatory ghrelin system in gastrectomized rats. 2010 Int J Pept pmid:20721337
Pulkkinen L et al. Ghrelin in diabetes and metabolic syndrome. 2010 Int J Pept pmid:20700400
Schwandt SE et al. Differential roles for octanoylated and decanoylated ghrelins in regulating appetite and metabolism. 2010 Int J Pept pmid:20700399
Giannakou SA et al. In vitro evaluation of nimodipine permeation through human epidermis using response surface methodology. 2002 Int J Pharm pmid:12086718
Yuan JS et al. Linker-based lecithin microemulsions for transdermal delivery of lidocaine. 2008 Int J Pharm pmid:17904775
Gwak HS and Chun IK Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. 2002 Int J Pharm pmid:11891070
Keel TR et al. AFM studies of the crystallization and habit modification of an excipient material, adipic acid. 2004 Int J Pharm pmid:15265558
Chen Y et al. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. 2015 Int J Pharm pmid:25841571
Damitz R and Chauhan A Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. 2015 Int J Pharm pmid:25839419
Sobczak M et al. Synthesis and study of controlled release of ofloxacin from polyester conjugates. 2010 Int J Pharm pmid:20888401
Choi A et al. The effects of fatty acids in propylene glycol on the percutaneous absorption of alendronate across the excised hairless mouse skin. 2008 Int J Pharm pmid:18329198
Wang S et al. Enhancing effect of Labrafac Lipophile WL 1349 on oral bioavailability of hydroxysafflor yellow A in rats. 2008 Int J Pharm pmid:18417306
Djordjevic L et al. Characterization of caprylocaproyl macrogolglycerides based microemulsion drug delivery vehicles for an amphiphilic drug. 2004 Int J Pharm pmid:15129969
Anraku M et al. The role of N-acetyl-methioninate as a new stabilizer for albumin products. 2007 Int J Pharm pmid:17045433
Yamamoto A et al. Enhanced transdermal delivery of phenylalanyl-glycine by chemical modification with various fatty acids. 2003 Int J Pharm pmid:12480278
Zhang GG and Grant DJ Incorporation mechanism of guest molecules in crystals: solid solution or inclusion? 1999 Int J Pharm pmid:10370203
Chen S et al. Triblock copolymers: synthesis, characterization, and delivery of a model protein. 2005 Int J Pharm pmid:15620860
Li P et al. Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. 2005 Int J Pharm pmid:15607255
Yuan JS et al. Effect of surfactant concentration on transdermal lidocaine delivery with linker microemulsions. 2010 Int J Pharm pmid:20363304
Nguyen CA et al. Cell interaction studies of PLA-MePEG nanoparticles. 2003 Int J Pharm pmid:12615412
Weight MJ et al. Cholesterol-ascorbic acid interactions in guinea pig liver homogenates, and in the in situ perfused liver: relationship between ascorbic acid status and cholesterol and bile acid synthesis from mevalonate. 1982 Int J Vitam Nutr Res pmid:7174228
Kandula M et al. Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. 2016 Int. Immunopharmacol. pmid:27716592
Kashiwagi S et al. Safety of the long-acting neuraminidase inhibitor laninamivir octanoate hydrate in post-marketing surveillance. 2012 Int. J. Antimicrob. Agents pmid:22871369
Garcia-Esteller SC et al. Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo. 1982 Int. J. Biochem. pmid:7106360
Moore KH et al. Hepatic hydrolysis of octanoyl-CoA and valproyl-CoA in control and valproate-fed animals. 1988 Int. J. Biochem. pmid:2895026
Spydevold O and Hokland B Release of leucine and isoleucine metabolites by perfused skeletal muscle and liver of rat. 1983 Int. J. Biochem. pmid:6617955
Bryła J and Niedzwiecka A The stimulatory effect of oleate on citrulline formation from carbamoyl phosphate and ornithine in rat-liver mitochondria: the relation to ornithine uptake. 1983 Int. J. Biochem. pmid:6617963
Wu G and Thompson JR Effect of pyruvate, octanoate and glucose on leucine degradation in skeletal muscle from fed and fasted chicks. 1988 Int. J. Biochem. pmid:3371527
Tuman RW et al. Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid (TDGA) on glucose and fatty acid oxidation in isolated rat soleus muscle. 1988 Int. J. Biochem. pmid:3350201
Veerkamp JH et al. Interaction of short-chain and branched-chain fatty acids and their carnitine and CoA esters and of various metabolites and agents with branched-chain 2-oxo acid oxidation in rat muscle and liver mitochondria. 1985 Int. J. Biochem. pmid:3934010
Drozak J et al. Contribution of L-3,4-dihydroxyphenylalanine metabolism to the inhibition of gluconeogenesis in rabbit kidney-cortex tubules. 2005 Int. J. Biochem. Cell Biol. pmid:15778090
Blanco E et al. Electrophoretic and spectroscopic characterization of the protein patterns formed in different surfactant solutions. 2008 Int. J. Biol. Macromol. pmid:17928047
Fontaine P et al. Medium chain length polyhydroxyalkanoates biosynthesis in Pseudomonas putida mt-2 is enhanced by co-metabolism of glycerol/octanoate or fatty acids mixtures. 2017 Int. J. Biol. Macromol. pmid:28174083
Ho IC et al. Structure and polymer form of poly-3-hydroxyalkanoates produced by Pseudomonas oleovorans grown with mixture of sodium octanoate/undecylenic acid and sodium octanoate/5-phenylvaleric acid. 2007 Int. J. Biol. Macromol. pmid:16919325
Lee MY et al. Synthesis of chitosan-based polymeric surfactants and their adsorption properties for heavy metals and fatty acids. 2005 Int. J. Biol. Macromol. pmid:16011843
Simon-Colin C et al. Biosynthesis and characterization of polyhydroxyalkanoates by Pseudomonas guezennei from alkanoates and glucose. 2012 Int. J. Biol. Macromol. pmid:22947450
Hassan N et al. Rheological properties of ovalbumin hydrogels as affected by surfactants addition. 2011 Int. J. Biol. Macromol. pmid:21262258
Godet MC et al. Inclusion/exclusion of fatty acids in amylose complexes as a function of the fatty acid chain length. 1995 Int. J. Biol. Macromol. pmid:8789347
Ballistreri A et al. Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids. 2001 Int. J. Biol. Macromol. pmid:11518582
Chung DM et al. Intracellular degradation of two structurally different polyhydroxyalkanoic acids accumulated in Pseudomonas putida and Pseudomonas citronellolis from mixtures of octanoic acid and 5-phenylvaleric acid. 2001 Int. J. Biol. Macromol. pmid:11718820
Bardi L et al. Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. 1999 Int. J. Food Microbiol. pmid:10357281
Nobmann P et al. The antimicrobial efficacy and structure activity relationship of novel carbohydrate fatty acid derivatives against Listeria spp. and food spoilage microorganisms. 2009 Int. J. Food Microbiol. pmid:19012983
Kim SA and Rhee MS Predictive model and optimization of a combined treatment of caprylic acid and citric acid for the reduction of Escherichia coli O157:H7 using the response surface methodology. 2015 Int. J. Food Microbiol. pmid:25544642
Viegas CA and Sá-Correia I Effects of low temperatures (9-33 degrees C) and pH (3.3-5.7) in the loss of Saccharomyces cerevisiae viability by combining lethal concentrations of ethanol with octanoic and decanoic acids. 1997 Int. J. Food Microbiol. pmid:9039572
Chang SS et al. Inactivation of Escherichia coli O157:H7 and Salmonella spp. on alfalfa seeds by caprylic acid and monocaprylin. 2010 Int. J. Food Microbiol. pmid:20926150
McLay JC et al. Inhibition of bacterial foodborne pathogens by the lactoperoxidase system in combination with monolaurin. 2002 Int. J. Food Microbiol. pmid:11883670
Centeno JA et al. Recovering traditional raw-milk Tetilla cheese flavour and sensory attributes by using Kocuria varians and Yarrowia lipolytica adjunct cultures. 2017 Int. J. Food Microbiol. pmid:28384620
Jang HI and Rhee MS Inhibitory effect of caprylic acid and mild heat on Cronobacter spp. (Enterobacter sakazakii) in reconstituted infant formula and determination of injury by flow cytometry. 2009 Int. J. Food Microbiol. pmid:19500867
Choi MJ et al. New decontamination method based on caprylic acid in combination with citric acid or vanillin for eliminating Cronobacter sakazakii and Salmonella enterica serovar Typhimurium in reconstituted infant formula. 2013 Int. J. Food Microbiol. pmid:24042002
St-Onge MP et al. Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. 2003 Int. J. Obes. Relat. Metab. Disord. pmid:12532160
Büllesbach EE and Schwabe C Structural contribution of the A-chain loop in relaxin. 1995 Sep-Oct Int. J. Pept. Protein Res. pmid:8537177
Huang L et al. Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for breast cancer therapy. 2011 Integr Biol (Camb) pmid:21938302
Nguyen NQ et al. Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy. 2013 Intensive Care Med pmid:23471513
Slater C et al. Analysis of 13C-mixed triacylglycerol in stool by bulk (EA-IRMS) and compound specific (GC/MS) methods. 2002 Isotopes Environ Health Stud pmid:12219984
Schommartz B et al. Significance of diagnostic parameters in [13C]octanoic acid gastric emptying breath tests. 1998 Isotopes Environ Health Stud pmid:9854848
Perri F et al. 13C-octanoic acid breath test: a reliable tool for measuring gastric emptying. 1998 Ital J Gastroenterol Hepatol pmid:9675662
Vincenzini MT et al. In vivo effects of octanoate and oleate on glucose-6-phosphate dehydrogenase during germination of Pinus pinea seeds. 1975 Nov-Dec Ital. J. Biochem. pmid:1218971
Leverve XM and Fontaine E Role of substrates in the regulation of mitochondrial function in situ. 2001 Sep-Nov IUBMB Life pmid:11798036
Chudasama A et al. Investigation of microemulsion system for transdermal delivery of itraconazole. 2011 J Adv Pharm Technol Res pmid:22171289
Patel J et al. Formulation and development of a self-nanoemulsifying drug delivery system of irbesartan. 2011 J Adv Pharm Technol Res pmid:22171286
SCHWABE AD et al. OCTANOIC ACID ABSORPTION AND OXIDATION IN HUMANS. 1964 J Appl Physiol pmid:14155309
Salimon J et al. Synthesis and physical properties of estolide ester using saturated Fatty Acid and ricinoleic Acid. 2011 J Autom Methods Manag Chem pmid:22007150
Akdemir ZS et al. Preparation of biocompatible, UV-cured fumarated poly(ether-ester)-based tissue-engineering hydrogels. 2011 J Biomater Sci Polym Ed pmid:20566062
Pandey A and Aswath PB Microwave synthesis of poly(L-lactic acid). 2009 J Biomater Sci Polym Ed pmid:19105899
Jung Y et al. Application of an elastic biodegradable poly(L-lactide-co-epsilon-caprolactone) scaffold for cartilage tissue regeneration. 2008 J Biomater Sci Polym Ed pmid:18644232
He B et al. Synthesis and characterization of functionalized biodegradable poly(DL-lactide-co-RS-beta-malic acid). 2008 J Biomed Mater Res A pmid:18181093
Gorna K and Gogolewski S Preparation, degradation, and calcification of biodegradable polyurethane foams for bone graft substitutes. 2003 J Biomed Mater Res A pmid:14613229
Lee SH et al. Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering. 2003 J Biomed Mater Res A pmid:12833428
Iwasaki Y et al. Reduced adhesion of blood cells to biodegradable polymers by introducing phosphorylcholine moieties. 2003 J Biomed Mater Res A pmid:12734808
Oiso S et al. Establishment of a gastric cell-based assay system for exploring inhibitors of octanoylated ghrelin production. 2013 J Biomol Screen pmid:23704134
Azulay DO et al. Stochastic simulations of the exponential-beta function as an assessment of the validity of the choice of the Wagner-Nelson method for the analysis of ¹³C-octanoic acid breath tests. 2010 J Breath Res pmid:21383478
Paromov V et al. Sulfur mustard toxicity following dermal exposure: role of oxidative stress, and antioxidant therapy. 2007 J Burns Wounds pmid:18091984
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011. 2011 J Cachexia Sarcopenia Muscle pmid:22476871
Calandra P et al. Emerging dynamics in surfactant-based liquid mixtures: octanoic acid/bis(2-ethylhexyl) amine systems. 2012 J Chem Phys pmid:22360203
Piett V et al. Enantioseparation of anionic analytes by non-aqueous capillary electrophoresis using quinine and quinidine derivatives as chiral counter-ions. 2000 J Chromatogr A pmid:11100848
Piette V et al. Non-aqueous capillary electrophoretic enantioseparation of N-derivatized amino acids using cinchona alkaloids and derivatives as chiral counter-ions. 2000 J Chromatogr A pmid:10839155
Stanley FE et al. Rapid determination of surfactant critical micelle concentrations using pressure-driven flow with capillary electrophoresis instrumentation. 2009 J Chromatogr A pmid:19836753
Baeyens WR et al. Application of the restricted-access precolumn packing material alkyl-diol silica in a column-switching system for the determination of ketoprofen enantiomers in horse plasma. 2000 J Chromatogr A pmid:10735295
Févrie P et al. Separation of glyceride positional isomers by silver ion chromatography. 2001 J Chromatogr A pmid:11510559
Naik AD et al. Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media. 2011 J Chromatogr A pmid:21176908
Piette V et al. Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors. 2002 J Chromatogr A pmid:12831205
Macko T et al. Elution behavior of polyethylene in polar mobile phases on a non-polar sorbent. 2003 J Chromatogr A pmid:12647822
Piette V et al. Enantiomer separation of N-protected amino acids by non-aqueous capillary electrophoresis and high-performance liquid chromatography with tert.-butyl carbamoylated quinine in either the background electrolyte or the stationary phase. 2003 J Chromatogr A pmid:12613837
Rimmer DA et al. Determination of organo-zinc based fungicides in timber treatments employing gas chromatographic analysis with mass selective detection and/or inductively coupled plasma atomic emission spectroscopy. 2001 J Chromatogr A pmid:11587339
Liu Z et al. Purification of human immunoglobulins A, G and M from Cohn fraction II/III by small peptide affinity chromatography. 2012 J Chromatogr A pmid:23026261