octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vinay P et al. | Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. | 1976 | Am. J. Physiol. | pmid:970471 |
| Barbee RW et al. | T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. | 1988 | Am. J. Physiol. | pmid:2830793 |
| McDaniel HG | Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. | 1975 | Am. J. Physiol. | pmid:1211489 |
| Burns AH and Reddy WJ | Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. | 1978 | Am. J. Physiol. | pmid:727249 |
| REES ED and KLINE DL | Metabolism of octanoate by fatty liver slices. | 1957 | Am. J. Physiol. | pmid:13470069 |
| Beaufrere B et al. | Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. | 1985 | Am. J. Physiol. | pmid:3895976 |
| Barron JT et al. | Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. | 1996 | Am. J. Physiol. | pmid:8764234 |
| Bonen A et al. | Palmitate transport and fatty acid transporters in red and white muscles. | 1998 | Am. J. Physiol. | pmid:9725814 |
| Azain MJ and Ontko JA | An explanation for decreased ketogenesis in the liver of the obese Zucker rat. | 1989 | Am. J. Physiol. | pmid:2552844 |
| Witters LA and Trasko CS | Regulation of hepatic free fatty acid metabolism by glucagon and insulin. | 1979 | Am. J. Physiol. | pmid:157075 |
| Bielefeld DR et al. | Altered sensitivity of chronic diabetic rat heart to calcium. | 1983 | Am. J. Physiol. | pmid:6362427 |
| REICH WJ et al. | The treatment of monilial vaginitis with caprylic acid. | 1953 | Am. J. Obstet. Gynecol. | pmid:13016687 |
| Talley NJ et al. | Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? | 2001 | Am. J. Gastroenterol. | pmid:11374677 |
| Vanheel H et al. | Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. | 2017 | Am. J. Gastroenterol. | pmid:27958284 |
| Lee JS et al. | Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. | 2000 | Am. J. Gastroenterol. | pmid:11051344 |
| Cappello G et al. | Gastric emptying of a solid-liquid meal measured with 13C octanoic acid breath test and real-time ultrasonography: a comparative study. | 2000 | Am. J. Gastroenterol. | pmid:11095323 |
| Rabinowitz JL et al. | The effects of intravenous sodium octanoate on the rhesus monkey. | 1978 | Am. J. Gastroenterol. | pmid:96693 |
| Choi MG et al. | Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. | 1998 | Am. J. Gastroenterol. | pmid:9448183 |
| Miele L et al. | Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test. | 2003 | Am. J. Gastroenterol. | pmid:14572600 |
| Perri F et al. | Patterns of symptoms in functional dyspepsia: role of Helicobacter pylori infection and delayed gastric emptying. | 1998 | Am. J. Gastroenterol. | pmid:9820377 |