octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kadota Y et al. | Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. | 2015 | Metab. Clin. Exp. | pmid:26104959 |
Epprecht L et al. | Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal. | 2015 | J. Neurol. | pmid:26048686 |
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Pesce P et al. | Gastric and masticatory performances in full-arch immediate loading rehabilitated patients. | 2015 | J Oral Rehabil | pmid:25882620 |
Kim SA and Rhee MS | Synergistic antimicrobial activity of caprylic acid in combination with citric acid against both Escherichia coli O157:H7 and indigenous microflora in carrot juice. | 2015 | Food Microbiol. | pmid:25846927 |
RodrÃguez-Moyá M and Gonzalez R | Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. | 2015 | J Proteomics | pmid:25845584 |
Chen Y et al. | Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. | 2015 | Int J Pharm | pmid:25841571 |
Damitz R and Chauhan A | Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. | 2015 | Int J Pharm | pmid:25839419 |
Royce LA et al. | Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity. | 2015 | Metab. Eng. | pmid:25839166 |
Oiso S et al. | Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. | 2015 | J Oleo Sci | pmid:26521811 |
Fredrickson J et al. | The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model. | 2015 | J. Assist. Reprod. Genet. | pmid:26342329 |
Kajimoto M et al. | Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26232235 |
Lemarié F et al. | Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. | 2015 | PLoS ONE | pmid:26196391 |
Xu J et al. | In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. | 2015 | Chem. Commun. (Camb.) | pmid:25792085 |
Alonso C et al. | Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol. | 2015 | J. Pharm. Pharmacol. | pmid:25645286 |
Kandula M et al. | Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. | 2016 | Int. Immunopharmacol. | pmid:27716592 |
Kateja N et al. | Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR). | 2016 | Biotechnol J | pmid:27447837 |
Lemarié F et al. | Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. | 2016 | Biochim. Biophys. Acta | pmid:27317984 |