octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Maddaiah VT | Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3977937 |
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Duée PH et al. | Development and regulation of ketogenesis in isolated hepatocytes from newborn rabbits. | 1985 | Reprod Nutr Dev | pmid:3992001 |
Lee SM et al. | Prevention of the metabolic effects of 2-tetradecylglycidate by octanoic acid in the genetically diabetic mouse (db/db). | 1985 | Biochem Med | pmid:3994695 |
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Hütter JF et al. | Effect of fatty acid oxidation on efficiency of energy production in rat heart. | 1985 | Am. J. Physiol. | pmid:4051011 |
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Strieleman PJ et al. | Fatty acid activation of the reconstituted brown adipose tissue mitochondria uncoupling protein. | 1985 | J. Biol. Chem. | pmid:4055740 |
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Zieve L et al. | Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat. | 1985 | J. Lab. Clin. Med. | pmid:4056569 |
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Dhopeshwarkar GA and Subramanian C | Lipogenesis in the developing brain: utilization of radioactive leucine, isoleucine, octanoic acid and beta-hydroxybutyric acid. | 1979 | Lipids | pmid:423709 |
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Miller TB | Cardiac performance of isolated perfused hearts from alloxan diabetic rats. | 1979 | Am. J. Physiol. | pmid:443443 |
Debeer LJ et al. | Effects of octanoate and oleate on energy metabolism in the perfused rat liver. | 1974 | Eur. J. Biochem. | pmid:4434997 |
Lemieux G et al. | Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. | 1979 | Am. J. Physiol. | pmid:464062 |
Strong CR and Dils R | Fatty acid biosynthesis in rabbit mammary gland during pregnancy and early lactation. | 1972 | Biochem. J. | pmid:4643704 |
Sheikh MI | Renal handling of phenol red. I. A comparative study on the accumulation of phenol red and p-aminohippurate in rabbit kidney tubules in vitro. | 1972 | J. Physiol. (Lond.) | pmid:4647268 |
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Spydevold O | The effect of octanoate and palmitate on the metabolism of valine in perfused hindquarter of rat. | 1979 | Eur. J. Biochem. | pmid:467425 |
Morrow RJ et al. | Functional utilization of palmitate, octanoate, and glucose by the isolated rat heart. | 1973 | Proc. Soc. Exp. Biol. Med. | pmid:4683244 |
Stewart HB et al. | Intermediates in fatty acid oxidation. | 1973 | Biochem. J. | pmid:4722901 |