octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
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Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ohkubo Y et al. | Presence and properties of acyl coenzyme A synthetase for medium-chain fatty acids in rat intestinal mucosa. | 1992 | Digestion | pmid:1386328 |
| Kim CS et al. | Octanoic acid produces accumulation of monoamine acidic metabolites in the brain: interaction with organic anion transport at the choroid plexus. | 1992 | J. Neurochem. | pmid:1372345 |
| DIANZANI MU and MARINARI U | The octanoate oxidation by mitochondria from faty livers. | 1961 | Biochim. Biophys. Acta | pmid:13722612 |
| Favre-Bulle O et al. | Bioconversion of n-octane to octanoic acid by a recombinant Escherichia coli cultured in a two-liquid phase bioreactor. | 1991 | Biotechnology (N.Y.) | pmid:1367010 |
| Kristev A et al. | Effects of the medium chain octanoic fatty acid on the contractile activity of vascular smooth muscle tissues. | 1992 | Folia Med (Plovdiv) | pmid:1364081 |
| Berger M et al. | Glucose metabolism in perfused skeletal muscle. Effects of starvation, diabetes, fatty acids, acetoacetate, insulin and exercise on glucose uptake and disposition. | 1976 | Biochem. J. | pmid:136249 |
| Prip-Buus C et al. | Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells. | 1992 | Eur. J. Biochem. | pmid:1356769 |
| LOSSOW WJ and CHAIKOFF IL | Secretion of intravenously administered tripalmitin-1-C14 and octanoate-1-C14 into milk by the lactating rat. | 1958 | J. Biol. Chem. | pmid:13502382 |
| REES ED and KLINE DL | Metabolism of octanoate by fatty liver slices. | 1957 | Am. J. Physiol. | pmid:13470069 |
| BROWN GW et al. | The oxidative metabolic pattern of mouse hepatoma C954 as studied with C14-labeled acetates, propionate, octanoate, and glucose. | 1956 | Cancer Res. | pmid:13343123 |
| LOSSOW WJ et al. | The action of insulin in sparing fatty acid oxidation: a study with palmitic acid-1-C14 and octanoate-1-C14. | 1956 | J. Biol. Chem. | pmid:13331942 |
| Stace PB et al. | Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. | 1992 | Biochim. Biophys. Acta | pmid:1319745 |
| CHAPMAN DD et al. | A comparison of the oxidation of octanoate-1-C14, -7-C14, and butyrate-1-C14 by neoplastic and normal mouse tissues. | 1954 | Cancer Res. | pmid:13160966 |
| BROWN GW et al. | On the unequal conversion of the carboxyl and seventh carbons of octanoate to CO2 by liver slices. | 1954 | Arch. Biochem. Biophys. | pmid:13159319 |
| GEYER RP et al. | Effect of pyruvate on octanoate metabolism as influenced by potassium and lithium. | 1953 | J. Biol. Chem. | pmid:13084632 |
| REICH WJ et al. | The treatment of monilial vaginitis with caprylic acid. | 1953 | Am. J. Obstet. Gynecol. | pmid:13016687 |
| Giron D et al. | Analysis of mono-, di- and triglycerides in pharmaceutical excipients by capillary supercritical fluid chromatography. | 1992 Oct-Dec | J Pharm Biomed Anal | pmid:1298389 |
| Kaiya H et al. | Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. | 2003 | Endocrinology | pmid:12970156 |
| Richards JG et al. | Palmitate movement across red and white muscle membranes of rainbow trout. | 2004 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12969874 |
| Nakajima I et al. | Growth arrest by octanoate is required for porcine preadipocyte differentiation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12963048 |
| Hiraoka T et al. | Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats. | 2003 | Physiol. Behav. | pmid:12954413 |
| Johnston A et al. | Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. | 2003 | Biologicals | pmid:12935811 |
| Vincent G et al. | Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12933348 |
| Guy JE et al. | The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. | 2003 | J. Mol. Biol. | pmid:12927540 |
| Dieterle F et al. | Urinary nucleosides as potential tumor markers evaluated by learning vector quantization. | 2003 | Artif Intell Med | pmid:12927336 |
| Lu XY et al. | Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. | 2004 | Appl. Microbiol. Biotechnol. | pmid:12920488 |
| Massillon D et al. | Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. | 2003 | J. Biol. Chem. | pmid:12915406 |
| Wang Z and Zhang Q | [Study on pulmonary delivery system of salmon calcitonin in rats]. | 2003 | Beijing Da Xue Xue Bao | pmid:12914259 |
| Boushaba R et al. | Kinetics of whole serum and prepurified IgG digestion by pepsin for F(ab')2 manufacture. | Biotechnol. Prog. | pmid:12892479 | |
| de Assis DR et al. | Evidence that antioxidants prevent the inhibition of Na+,K(+)-ATPase activity induced by octanoic acid in rat cerebral cortex in vitro. | 2003 | Neurochem. Res. | pmid:12892042 |
| Walton ME et al. | Octanoate oxidation measured by 13C-NMR spectroscopy in rat skeletal muscle, heart, and liver. | 2003 | J. Appl. Physiol. | pmid:12882988 |
| Ho TS et al. | Liquid-phase microextraction of hydrophilic drugs by carrier-mediated transport. | 2003 | J Chromatogr A | pmid:12862372 |
| Randriamahefa S et al. | Fourier transform infrared spectroscopy for screening and quantifying production of PHAs by Pseudomonas grown on sodium octanoate. | 2003 Jul-Aug | Biomacromolecules | pmid:12857097 |
| Ebert D et al. | Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy. | 2003 | J. Neurosci. | pmid:12843297 |
| Kuge Y et al. | Characteristic brain distribution of 1-(14)C-octanoate in a rat model of focal cerebral ischemia in comparison with those of (123)I-IMP and (123)I-iomazenil. | 2003 | J. Nucl. Med. | pmid:12843233 |
| Lee SH et al. | Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering. | 2003 | J Biomed Mater Res A | pmid:12833428 |
| Piette V et al. | Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors. | 2002 | J Chromatogr A | pmid:12831205 |
| Kudo N and Kawashima Y | Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals. | 2003 | J Toxicol Sci | pmid:12820537 |
| Zhou S et al. | Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) block copolymers: characterization and their use as drug carriers for a controlled delivery system. | 2003 | Biomaterials | pmid:12809785 |
| Cai Q et al. | Synthesis and characterization of biodegradable polylactide-grafted dextran and its application as compatilizer. | 2003 | Biomaterials | pmid:12809784 |
| Han J et al. | Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats. | 2003 | Obes. Res. | pmid:12805394 |
| Iwahashi H et al. | The formation of the 7-carboxyheptyl radical from 13-hydroperoxy-9,11-octadecadienoic acid catalyzed by hemoglobin and myoglobin under anaerobic conditions. | 2003 | J. Biochem. | pmid:12801921 |
| Winiarska K et al. | Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. | 2003 | Metab. Clin. Exp. | pmid:12800101 |
| Claessens YE et al. | Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. | 2003 | Crit Care | pmid:12793872 |
| Zahn A et al. | Measurement of gastric emptying by 13C-octanoic acid breath test versus scintigraphy in diabetics. | 2003 | Z Gastroenterol | pmid:12772050 |
| Oettl K et al. | An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12767923 |
| Aiston S et al. | Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase. | 2003 | Diabetes | pmid:12765941 |
| Li C et al. | Covalent binding of 2-phenylpropionyl-S-acyl-CoA thioester to tissue proteins in vitro. | 2003 | Drug Metab. Dispos. | pmid:12756204 |
| Hamel FG et al. | In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. | 2003 | Endocrinology | pmid:12746301 |
| Crane J et al. | Triacylglycerols determine the unusual storage physiology of Cuphea seed. | 2003 | Planta | pmid:12743824 |